Help interpreting please - thank you!

[ChrisH100]

Hello All - When I was test in Feb 2017 my anti thyroid microtonal ab wa 722 iu / ml. I had no result against anto- too. In sept if same year I got my bloods tested by medichecks - my thyroglobulin antibody tgab was 620 and my tpo- ab 222 iu/ml. Can someone explain the significance of each - are microsomal and anti- tpo the same thing and whether my tpo antibodies have reduced - thank you and best wishes Chris

[SeasideSusie Remembering]

Microsomal antibodies are TPO antibodies.

"my anti thyroid microtonal ab wa 722 iu / ml

my thyroglobulin antibody tgab was 620 and my tpo- ab 222 iu/ml. "

Yes, on the Medichecks test your TPO antibodies had reduced. Don't forget that antibodies fluctuate though, they may not be the same now as they were in September.

[helvella Administrator in reply to SeasideSusie]

SeasideSusie,

Quite right.

The term microsomal was used when the substance they are antigens to was unidentified. Thyroid Peroxidase was identified a long time ago - and most references now are to Thyroid Peroxidase antibodies rather than microsomal.

I am always concerned when we see reference to "microsomal antibodies". Are they that far out of date?

[ChrisH100 in reply to helvella]

Thanks seasidesusie - it certainly would seem so - do you know what the other test indicates?

[SeasideSusie Remembering in reply to ChrisH100]

Thyroglobulin? Another thyroid antibody. You are positive for both TPO and TG antibodies confirming autoimmune thyroid disease aka Hashimoto's.

[ChrisH100 in reply to helvella]

Sorry i meant helvella...

[ChrisH100 in reply to SeasideSusie]

Thanks seasidesusie !