Ray Peat - compendium of articles

[Heloise]

I thought this list of articles by Ray Peat might be handy to bookmark. Especially in the face of arrogant, medical mismanagement of our thyroid disorders. This is part of our own education so we can enhance our treatment and our health.

raypeat.com/articles/

[Mamapea1]

Thanks Heloise ~ there's so much info on there! You have been so helpful to me and many others ~ I hope you have a wonderful 2018 ~ you deserve it! Warmest wishes to you. Mamapea x

[WildDeer]

Thanks for this link Heloise.

I've just read his argument about aspirin enhancing the anti-inflammatory properties of T3. Very interesting.

All the Best for 2018!

[Heloise in reply to WildDeer]

And same to you WildDeer. May we all wise up for 2018.

[Jacs]

This is great Heloise, thanks 😄 Much interesting reading ahead

[Heloise in reply to Jacs]

Hi jacs, I went back to one of your posts about muscle deterioration. I was telling everyone to break insulin resistance by using apple cider vinegar. I lost a few pounds quickly and though I look better, I feel like much of it was muscle. How are you doing in that regard now. I saw your question about E and progesterone but I think the cream is better unless you know exactly what you need. I know we need to counteract all the estrogen we get.

[Jacs in reply to Heloise]

hi heloise, i'm still ageing so much quicker than any of my friends, including those 5-6 years older (hard to deal with particularly as till i was on my early 40's i passed for so much younger). my arms & legs have lost so much muscle and now i'm not exercising (temporary situation) expect it to get worse. that said i'm hoping to retire early later this year & can then spend more time looking after myself and getting on top of things again.

Thanks for showing an interest, but also for taking time to post useful, informative & interesting articles

xxx

[Heloise in reply to Jacs]

Oh, I do hope you find some answers. I think Hypothyroidism is a muscle and nerve impediment. I hope you look into the proteolytic enzymes.

I've been reading more about DHEA. I looked into it a long time ago and was kind of afraid of it but now that it's called the youth pill I've decided to try it. If you take any adrenal support you should use it with DHEA. It used to give me a headache which now I believe was a good sign. I really hate being my own guinea pig but what are we to do?

Are you eating good protein? Also, collagen is in more than just your skin and even bones. Vitamin C helps to develop that. I have used the crystals and put them in my water or fruit juice and sip anytime. Easier than pills.

Take care, jacs.

[Joanneconnor]

Thanks, think Ray Pete is going to keep me busy 😂😂

[Heloise in reply to Joanneconnor]

LOL, maybe I should have just posted one article at a time. I hope it helps you, I'm learning lots.

[Joanneconnor in reply to Heloise]

No I love to read I have a few issues so I will be looking at them first thanks Heloise

[Joanneconnor]

I have problems with my muscles, they hurt so much even going up two stories to our 3 floor bedroom

[Heloise in reply to Joanneconnor]

A while ago I figured we are making too much lactic acid. We don't detox well so it builds up. I was reading one of these articles and it was mentioned again that we are creating lactic acid (usually it's by exercising) but there may be another reason. Not sure how to get rid of it.

[Joanneconnor in reply to Heloise]

Yes I thought it was lactic acid, I have tried NAC supposed to get rid of mucin, didn't see any change

[Heloise in reply to Joanneconnor]

NAC does thin mucous so you would think it would. It definitely helps in the respiratory system. It may take quite a while. Serrapeptase also works on mucous. youtube.com/watch?v=XRUz9ZC...(Not working as expected?)

[Heloise in reply to Joanneconnor]

I was reading his Cancer page and he talks about lactic acid. Being too alkaline is as bad as too acid.

When the pH of a protein gel becomes more alkaline, it swells.

The electrical activation of a nerve causes a quick shift towards internal alkalinity

(Endres, et al., 1986), followed by a sudden increase in lactic acid production. Although

increased lactic acid causes acidity of an irritated or inflamed region, the conversion of

pyruvic acid to lactic acid causes the interior of the stressed cell to become more

alkaline, causing it to swell. This is the same process that causes the familiar swelling of tired muscles.

If blood vessels swell, the delivery of oxygen may be restricted, and hypoxia causes

more intense swelling, because more lactic acid is produced, and less oxidized. This swelling pressure resembles an increase of osmolarity. For over 100 years, it has been customary to treat shock with "isotonic" fluids, which are in balance with well oxygenated tissues, with approximately 290 milliosmoles per liter, but this usually causes edema, swelling, and weight gain. Stressed tissues have been found to be in balance with fluids of much higher osmolarity, for example 372 mOsm/L (Tranum-

Jensen, et al., 1981), and sometimes much higher.

Apart from its acidity, lactic acid acts as an excitatory signal. A very slight increase

above the normal amount of lactic acid in the body fluids excites sensitive cells, and the

amounts reached in inflamed tissues and in cancers will excite even stable cells such as

myelinated nerves (Uchida and Murao, 1975).

[Joanneconnor in reply to Heloise]

Wow! Lots of info, much of it I don't understand, am I right in saying I need to drink isotonic drinks? Sorry is there anything I can do?

[Heloise in reply to Joanneconnor]

Maybe in an acute stage, the above notes said: the conversion of

pyruvic acid to lactic acid causes the interior of the stressed cell to become more alkaline, causing it to swell. This is the same process that causes the familiar swelling of tired muscles.

I looked up pyruvic acid.

Pyruvic acid, or pyruvate, is the result of the degradation of glucose. During the degradation process, pyruvic acid is transformed into acetic acid. The brain, intestines, myocardium, and skeletal muscles can be the source of pyruvates. The accumulation of pyruvates can be found in cases of an over-exertion of the muscles, a deficiency in vitamin B1, diabetic acidosis, or certain leukemias. Too much pyruvates can cause vomiting, fatigue, loss of weight, or acute diarrhea in infants.

So, I wonder about the B1 deficiency. Izabelle Wentz had a series called the Thyroid Secret and said she took 600 mgs. of thiamine which is B1 for her brain fog.

So maybe you should try extra B1 and try to get your FT3 in a good range. Take a complex B even with extra B1, B5 and B12.

[Joanneconnor in reply to Heloise]

Oh right ok I'm getting my bloods don't tmoz the usual ones and a few others b12 vit d, ferritin but no magnesium? I think my t3 will be in top of range and t4 in middle hopefully, I might try get some b1 thanks

[Heloise in reply to Joanneconnor]

Very good, joanne. They won't give you the right test for magnesium anyway. B vitamins are extremely important but if you don't have the right bacteria, they will not metabolize so supplementing is important.

[Joanneconnor in reply to Heloise]

Ok do I just take magnesium any way

[Joanneconnor in reply to Joanneconnor]

Should I be taking a good probiotic maybe?

[Heloise in reply to Joanneconnor]

Definitely, your adrenals need tons. Take a lot.

I am not sure you need probiotics. The more I read, the less I think they work that well. You may do better eating fermented food like live sauerkraut. I think people use kumbucha but I've not tried it.

[Joanneconnor in reply to Heloise]

I did have high cortisol, but I think it's normal now. There's now way I'm eating that stuff, yuck 😂😂😂

[Heloise in reply to Joanneconnor]

Lol, then maybe you should get probiotics. There is also inulin, it's sweet and a prebiotic.

[Joanneconnor in reply to Heloise]

I watched the thyroid secret I don't remember that bit, lots of information

[Heloise in reply to Joanneconnor]

I'm looking at my notes from episode 9. Found this:

Betaine with pepsin can turn around fatigue and pain. Izabella said it made a huge difference because she was getting the nutrients now and it removed enough fatigue that she woke up at 6 a.m. ready to go. She took them after each meal.

Selenium and an enzyme called wobenzyme (pharmacy grade) can really reduce antibodies. It's a systemic enzyme (I've been using them myself) and it may reduce anti TPO's anti TG's. 5 tablets three time/day for 3 months also improved muscle pain, allowed an increase of exercise tolerance and a decrease in recovery time so you don't crash for three days. Izabella recommended butyrate for fueling probiotics. I looked this up:

Butyrate is a type of fatty acid that helps your gut work right, and it might be important for gut-related diseases from autoimmunity to obesity to colon cancer.

There has been a question of where probiotics survive the stomach but they recommended a rotation of different brands so you don't create another imbalance. When they work you will notice better movements and better clearing. There is another type of probiotic called Megaspor. The man who promoted these said his mother in law had suffered from allergies and asthma for 20 years. She couldn't go near any pets but within three weeks she was able to come into their house with their pets. The spores CAN survive the gut acids so are more effective.

[Joanneconnor in reply to Heloise]

I walk nearly 3 mile a day to work and back but I've noticed my legs look bigger I don't think I'm imagining it!

[shaws Administrator]

Thanks for posting. This is another doctor who speaks sense instead of nonsense.

[Heloise in reply to shaws]

Yes. Dr. Bergman calls him a genius but I do see a few things about nutrition that I wonder about. In fact Peat recommends sugar as sometimes necessary and essential fatty acids may not be. I'm still reading. Often his tests are on animals who do not have a microbriome as I recall from the Betrayal Series. There is such animosity between the two types of medicine it leaves you not knowing what to believe. He does tie in diabetes along with hypothyroidism.

[Joanneconnor in reply to Heloise]

Yes my identical twin sister has not long been diagnosed with type 1.5 diabetes and is on insulin, we have both been hypothyroid for 14 years

[Joanneconnor]

Lol, I don't really have fatigue as such just in my muscles,

[Heloise in reply to Joanneconnor]

My son had a 3rd floor apartment. I had to rest after each floor. So even though you do it almost every day, it hasn't gotten easier? Are your legs a little swollen?

[Joanneconnor in reply to Heloise]

Yes still suffer going up even a slight hill ok on straight for about a mile then starts hurting a lot to the point I can't walk properly no energy in muscles, no it hasn't got any easier I've been doing it for 6 weeks now, they're not puffy like water retention the just look larger on calves and muscle on front of legs

[Heloise in reply to Joanneconnor]

Yes, sounds very typical. This is why I hate to see people not getting their dose right or staying on Levo if it's not working. Magnesium is very, very important to your muscles, all of them. Also potassium is necessary and especially if you eat a lot of salt.

[Joanneconnor in reply to Heloise]

I think I have my levels right I'm on 2 grains thyroid s and 50 Levo should find out next week, I eat an enormous amount of salt, the only time I didn't put any on a meal was when doc gave me a booster dose of vit d3 haven't found the connection yet, but I've craved it for years

[Joanneconnor in reply to Heloise]

Is it cause by thyroid?

[Heloise in reply to Joanneconnor]

Your adrenals looking for minerals. Potassium actually might help get rid of some of the excess fluid. I know we need 400 mgs. a day but not sure how much you might get in your food. Maybe you could take a 200 of 250 with your magnesium and see if it helps.

[Joanneconnor in reply to Heloise]

Right ok yes I will try that thanks