Different antibodies: When you get the medichecks... - Thyroid UK

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Different antibodies

Danielj1 profile image
15 Replies

When you get the medichecks blood test there are 2 sets of antibody results

Just to confirm:

Is one type more important than the other ?

Do they respond differently to interventions?

Thanks

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Danielj1 profile image
Danielj1
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15 Replies
Marz profile image
Marz

I would advise having both tested - in case one is below range and the other not :-)

More info here:

thyroiduk.org.uk/tuk/about_...

You may have one or other raised, or both (like me) or none.

I can't comment on whether they respond differently to interventions as I don't know. :)

Danielj1 profile image
Danielj1 in reply to

Thanks - as a folllow up where I can find more on TG antibodies only a very brief mention on this site - genuinely trying to understand if one is more serious than the other etc

in reply toDanielj1

oops replied to my own post - see the reply below this.

greygoose profile image
greygoose in reply toDanielj1

You can't say that one is more serious than the other, it's just that some people have one raised, and some have the other. Most Hashi's people have raised TPO antibodies. But a good percentage have Tg antibodies raised. They both mean the same thing. They mean you have Hashi's. That's all.

The thyroglobulin antibodies are indicative of Hashimoto's, basically they're destroying your thyroid. The fewer you have, the better! It may help to go gluten-free, or even dairy-free. Taking a selenium supplement is also a good idea to help control them.

Some info here (it is quite hard to find useful info):

stopthethyroidmadness.com/l...

mayomedicallaboratories.com...

Danielj1 profile image
Danielj1

Thanks - can you infer anything if TPO responds well to supplement intervention and diet changes but TG remiains a lot “stickier”

Anyone experience this ?

Baobabs profile image
Baobabs in reply toDanielj1

Not sure. I was very proud when my anti-bodies reduced by 30% within 3 months of going gluten free and starting selenium supplementation but my GP claimed the reason was because my thyroid was gradually being destroyed and therefore the further along this road I was there was less and less for ant-bodies to destroy, hence the reduction in them. Not sure I believe him but that's no surprise!

Clutter profile image
Clutter in reply toDanielj1

DanielJ1,

No, there's nothing to be inferred from that other than TPO is responding but Tg isn't.

thyroiduk.org.uk/tuk/about_...

thyroiduk.org.uk/tuk/about_...

SlowDragon profile image
SlowDragonAdministrator

Medics tend to only consider TPO for confirming Hashimoto's

Patients with just high TG antibodies will often struggle to get considered as having Hashimoto's

TG antibodies can raised for other reasons

emedicine.medscape.com/arti...

Danielj1 profile image
Danielj1

There are a lot of comments to the effect that the end stage is full loss of thyroid function and disappearance of the gland itself.

There must be some/many here who that has happened to.

The weirdest thing is that it seems to me if you fix all the nutritional issues the very long list of hashi symptoms go pretty away.

And then you are left with feeling fine and the thought that maybe inside you are not. I find it all very puzzling - perhaps others here can get their head around better : )

Baobabs profile image
Baobabs in reply toDanielj1

Some Hashi sufferers do claim to have the condition in remission due to building blocks in place, gluten free diet etc. I presume this means the thyroid does not completely become destroyed? Recently I have also been pondering if indeed poor levels of recognised building blocks could lead to the onset of Hashimoto's. Oodles of research to be undertaken by willing professionals. I will ask my doctor next visit when I have another ultrasound to what extent the gland has been destroyed and how does he know? Not holding my breath for any answer let alone a plausible one, probably will just bluff and puff hot air as usual and wish a tornado would sweep me up and remove me from his office.

Danielj1 profile image
Danielj1

Baobabs exactly my point - instead of being positive about your dedication and commitment it’s all being discounted as par for the course and no stopping a dreadful outcome.

Who to believe as you say.

Baobabs profile image
Baobabs in reply toDanielj1

Medics probably think why bother when we're not going die with the disease and there's always good old reliable wave the magic wand, 'one size fits all' Levothyroxine as a 'go to'.

Danielj1 profile image
Danielj1

My finding thus far is that the nutritional changes including kelp have had far more impact on daily living than thyroxine. If I had not come to this site I would never really have known how vital supplements etc really are.

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