Antibodies raised: Thank you for guiding me to... - Thyroid UK

Thyroid UK

141,244 members166,489 posts

Antibodies raised

LesLiz22 profile image
5 Replies

Thank you for guiding me to Medichecks, from whom I've just received my test results:

TSH 2.69; Free Thyroxine 18.9; T4 91.6; T3 4.67 - all within normal range.

However, Thyroglobulin Antibody *344; Thyroid Peroxidase Antibodies *82.2Please can you explain what these raised antibody levels mean? The comment attached to my result says they're consistent with an autoimmune cause for my hypothyrodism but, please excuse my ignorance, I'm still not sure what that means.

I was diagnosed c.16 months ago, and am currently taking 75mg Levothyroxine.

Written by
LesLiz22 profile image
LesLiz22
To view profiles and participate in discussions please or .
Read more about...
5 Replies
shaws profile image
shawsAdministrator

The aim, when diagnosed with hypothyroidism and when taking thyroid hormone replacements, is a TSH of 1 or below. With Free T4 and Free T3 towards the upper part of the range. You haven't given the ranges only the results.

Your dose of 75mcg is too low and you need an increase to bring TSH to 1 or below.

Thyroid antibodies mean you have an Autoimmune Thyroid Disease commonly called Hashimoto's. The antibodies attack your thyroid gland and to reduce the attack (they wax and wane) going gluten-free can help reduce them. We do not want 'within normal range' we need optimum ranges. Treatment is the same as for hypothyroidism, i.e. levothyroxine.

LesLiz22 profile image
LesLiz22 in reply toshaws

Thank you. Your guidance is incredibly valuable in helping me to prep for seeing my GP, who had refused my recent request for a blood test, saying my TSH was ‘perfect’ at 1.12 back in September so there was no need to do any tests at this time, despite my symptoms.

Ranges:

TSH 2.69 (0.27-4.20);

Free Thyroxine 18.9 (12.00-22.00); Total T4 91.6 (59.00-154.00);

Free T3 4.67 (3.10-6.80); Thyroglobulin *344 (0.00-115.00); Thyroid Peroxidase Antibidies *82.2 (0.00-34.00).

Would an increase to 100mcg Levi likely be sufficient for me at this time? And do you think I am best to stay with my GP or ask to be referred to an endocrinologist at this stage?

SeasideSusie profile image
SeasideSusieRemembering

LesLiz22

Some info about Hashi's. Doctors tend to dismiss antibodies as of no importance and don't understand what Hashi's can do. Read, learn, understand and help yourself because you won't get much help from doctors where Hashi's is concerned.

chriskresser.com/the-gluten...

hypothyroidmom.com/hashimot...

stopthethyroidmadness.com/h...

stopthethyroidmadness.com/h...

As well as adopting a gluten free diet, supplementing with selenium L-selenomethionine 200mcg and keeping TSH suppressed can also help reduce antibodies.

Hashi's and gut/absorption problems tend to go hand in hand and very often low nutrient levels are the result. If not already tested, ask for

Vit D

B12

Folate

Ferritin

andnif ferritin is low you'll need

Iron Panel

Full Blood Count

If GP won't do them we have recommended labs that do home fingerprick (or venous blood draw) tests.

SlowDragon profile image
SlowDragonAdministrator

Essential to test vitamin D, folate, ferritin and B12. Always get actual results and ranges. Post results when you have them, members can advise

Your antibodies are high this is Hashimoto's, (also known by medics here in UK more commonly as autoimmune thyroid disease). About 90% of all hypothyroidism in Uk is due to Hashimoto's

With Hashimoto's, our gut can be badly affected. Low stomach acid can lead to poor absorption of vitamins. Low vitamin levels stop thyroid hormones working.

Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances. Most common by far is gluten

According to Izabella Wentz the Thyroid Pharmacist approx 5% with Hashimoto's are coeliac, but over 80% find gluten free diet helps significantly. Either due to direct gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)

But don't be surprised that GP or endo never mention gut, gluten or low vitamins. Hashimoto's is very poorly understood

Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and slowly lower TPO antibodies

thyroidpharmacist.com/artic...

thyroidpharmacist.com/artic...

amymyersmd.com/2017/02/3-im...

chriskresser.com/the-gluten...

scdlifestyle.com/2014/08/th...

drknews.com/changing-your-d...

LesLiz22 profile image
LesLiz22

Thanks for your guidance. Took my results to GP who acknowledged that I had Hashis but was clearly unimpressed I’d taken the initiative! I told him I was considering a gluten-free diet and he said I should have other tests incl one for Coeliac disease before I adapt my diet. Result just back: tissu transglutamin IgS lev: result: 1 u/mL (normal range: 0-6.9u/mL). Please can you explain what this means for me?

Not what you're looking for?

You may also like...

Endo stopping my levothyroxine, raised thyroid antibodies

Hi I am a newbie. My endo has stopped my150mcg levothyroxine based on below bloods done back in...
Rosa1 profile image

Antibodies

THYROID PEROXIDASE ANTIBODY 905.4 (<34) THYROGLOBULIN ANTIBODY 365.3 (<115) Went to GP about these...
Laurenjay profile image

Thyroid antibodies

TPO antibody 275 (<34) TG antibody >1400 (<115) Not sure what these are? Blue Horizon advised me...
Lunetta profile image

Negative antibodies

I got my second TFT result today which was worse than my first (TSH 16, FT4 10.4 and now below...
Blaziken profile image

Raised Antibodies

I have high Hashimoto antibodies, high gluten antibodies, and now PBC (primary Billiary Cirrhosis)...

Moderation team

See all
Jaydee1507 profile image
Jaydee1507Administrator
PurpleNails profile image
PurpleNailsAdministrator
SlowDragon profile image
SlowDragonAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.