As I have not been too well recently I asked my Gp for a cortisol test as I have had a head injury in the past and its likely that my pituitary is failing. My TSH has already failed and is permanently zero and my sex hormones (and sex drive) are non existent. My Gps reaction was that my Cortisol level -253 (range 150 to 500) is completely normal for a morning test. I am really struggling at the moment, even the slightest physical task leaves me shaking like a leaf and the constant nausea is getting unbearable. My normally well controlled asthma has ramped up and I seem to permanently need my inhalers. I am lightheaded and clumsy and the brain fog has descended again. I take 75mcg of T3 broken into small amounts daily and increasing or decreasing the dose has no effect. I have no energy and virtually a permanent headache. Anyone any ideas?