Is it Hashi? High TPOAb but no hyper periods.

[moniacho]

Hi all,

I’ve received my blood results and found out that I have TPO Ab above the range and TG Ab half way through the range. That means Hashimoto’s, right?

However, I have been hypo 17 years now and I never experienced periods of hyper that are supposed to be happening in Hashi. At least not in the last 10 years, not sure if I can remember before that. My levo dose was quite stable over the years, steadily increasing up to 125 in the first years and then only increased recently during pregnancy to 150. Never any sudden fluctuations. That suggests that my blood results were always quite steady.

What does it mean? Is Hashi just starting? Or is it already past destroying my thyroid and causing hormone increase due to cell death? Thank you for all the comments.

My current blood results:

TGAb 56.9 IU/ml [0-115]

TPOAb 46 IU/ml [0-34]

TSH <0.03 mu/L [0.2-6]

Free T4 19.9 pmol/L [10-20]

Free T3 5.6 pmol/L [3.5-7]

[Clutter]

Moniacho,

Thyroid peroxidase antibodies are positive for autoimmune thyroid disease (Hashimoto's). Hashimoto's causes 90% of hypothyroidism so you may have had it for a long time. The only way to tell whether your thyroid has been destroyed is to have an ultrasound scan of the thyroid.

Many people have found that 100% gluten-free diet is helpful in reducing Hashi flares, symptoms and eventually antibodies.

chriskresser.com/the-gluten...

thyroiduk.org.uk/tuk/about_...

You appear to be adequately dosed on 125mcg as TSH is suppressed, FT4 is top of range and FT3 is high in range.

[moniacho in reply to Clutter]

Thank you Clutter , I was trying to understand how could I have Hashi if I never experienced the periods of hyper symptoms. But I guess that the presence of antibodies confirms Hashi anyway. You are right, I may have had it from the beginning and just not recognising the hyper flare-ups...

[Clutter in reply to moniacho]

Moniacho,

You may have had hyper symptoms before you were diagnosed hypothyroid or you may not have experienced them at all. High antibodies confirms Hashimoto's now.

[Angel_of_the_North]

Feeling "normal" might have been as hyper as you ever got, esp if your hashis was caught fairly early/

[moniacho in reply to Angel_of_the_North]

Interesting thought Angel_of_the_North , thank you.

[foreversummer in reply to moniacho]

That's really interesting actually. I've often wondered why I did not get the hyper phases, but I do remember there were times when I felt absolutely fine, even to the point of getting into bed at night and being so fired up for the next day that I was quite excited - best way I can describe it. It was not unpleasant in any way and I just wish I could feel like that again now.

[SlowDragon Administrator]

So are you now strictly gluten free?

It might help low cortisol (on today's post)

What about vitamin D, folate, ferritin and B12

What supplements do you take

Vitamin C is good for adrenals too

[moniacho in reply to SlowDragon]

Hi SlowDragon . Yes, I am now strictly gluten/dairy/soy free but only since 7 weeks ago. I was dreading the change but it wasn’t that hard. Don’t feel any difference yet, but may have to wait up to 6months before feeling the effect.

My vitamin B12 was 308ng/L [180-910] last summer and I started taking 500ug/day B12 for at least 4months, then lowered to 2000ug/day. It was tested at some point again after that (I know it was pointless, but GP tested anyway) and was about 450 ng/L if I remember correctly (results at home). Surprisingly low, as I would have expected much higher result with all the B12 floating about in bloodstream. My iron, folate and ferritin were also tested last summer (iron 5umol/L [5-33], saturation iron binding capacity 8% [15-50], folate 16.7ng/ml [5.4-24], ferritin 55ug/L [10-291]). Since then I have been taking 3xFerrous Fumarate daily for 4 months, then lowered to 2xdaily. My vitD was 23.8 ng/mL last summer and I’ve been taking 5000IU/daily since then.

I also take Bcomplex, selenium, 2000ug VitC with my iron, K2 with my VitD, Magnesium and Betaine with Pepsin. Few days ago I added NAC and probiotic.

[SlowDragon Administrator in reply to moniacho]

Sounds like your doing all the right things

omega 3 perhaps

Or zinc is another to try

Remember to stop taking any supplements with biotin in 3-5 days prior to any blood tests

[moniacho in reply to SlowDragon]

Oh yes, I do take zinc. Completely forgot, so many of them I also already got Omega3 but will start it in few days when Im sure there is no reaction to NAC.