B12 level too high (not supplementing) - Thyroid UK

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B12 level too high (not supplementing)

34 Replies

Hello!

[Currently taking: 50-mcg Synthroid / 15-mcg Liothyronine]

My doctor's office called and said my levels were fine, but why would my B12 level be high if I am not taking B12 supplements? And shouldn't I have a higher level of Vitamin D?

Vitamin B12 (211-946 pg/mL) 1053

Folate (>3.0 ng/mL) 14.3

Vitamin D (30-100.0 ng/mL) 36.8

Thank you.

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34 Replies
shaws profile image
shawsAdministrator

You may be absorbing B12 from your food.

globalhealingcenter.com/nat...

Your B12 makes a change from others who have very low B12.

rudrafroo profile image
rudrafroo in reply to shaws

Vitamin B12 - tonzes.com/b12.htm This tablet took my Vitamin B12 levels from dangerously low to so high I can only take them every other day.

SeasideSusie profile image
SeasideSusieRemembering

Hidden As the unit of measurement of your Vit D test is ng/ml, then the recommended level is 40-60. So you're very close to the recommended level.

vitamindcouncil.org/i-teste...

It's when the unit of measurement is nmol/L (typical in the UK) that the recommended level is 100-150.

Sorry, I can't help with your B12 question.

thank you for the links and responses. both articles are informative (as usual) - the list of foods is super useful and the Vitamin D guidelines to increase levels is very helpful.

My brain fog and fatigue have been intermittent but particularly brutal lately. So I guess my concern was more towards the possibility of not utilizing B12 properly and thus the higher level on the test result … a possible pernicious anemia symptom?

And with my Vitamin D level so low based on the guidelines - I was considering supplementing to get this level higher.

humanbean profile image
humanbean

You might find this link interesting on the subject of high B12 without supplementing :

academic.oup.com/qjmed/arti...

There is a link to a PDF of the research paper near the top of the page. It is worth downloading and keeping a copy, in my opinion. Even your doctor might find it helpful - miracles might happen!

in reply to humanbean

Thank you!

I was thinking of searching the site for pertinent articles to print and take to him for my next visit. (this will be one of them) He seemed a bit reluctant to increase the dose of my liothyronine during my last visit. But honestly, I will have to read more carefully later - I'm not processing too well today :'(

humanbean profile image
humanbean in reply to

I imagine the reluctance to increase liothyronine is because so many CCGs are telling doctors they can't prescibe it and it is a "low value" medicine because everyone does well on Levo which is soooooo much cheaper.

in reply to humanbean

Perhaps. I was not like everyone and doing well on Levo alone. I have felt some improvements (lost 10-12 lbs.) since adding the T3. But over the years (diagnosed in 2006) I've found it to be a slow journey of ups and downs and a lot of guess work on my part. As I've said in a previous post, I am so grateful that I have found this site.

humanbean profile image
humanbean in reply to

I think anyone who does well on Levo wouldn't need the help of this forum, so you are in good company. :)

Silver_Fairy profile image
Silver_Fairy

Sorry, have to disagree with this statement 'Don't worry about your b12 level it can't be too high'. There are certain conditions that can increase the levels of B12. My levels were high, without supplementing and my GP did some other tests to rule out certain conditions.

Your levels are above range so your GP should really be looking into why.

in reply to Silver_Fairy

Thank you. This is why I posted the question. According to some very initial research I have done elevated b12 can be misleading and certainly cause for concern. I will follow up with my physician.

Nanaedake profile image
Nanaedake

If it was me I would not be worried about a B12 level like that. As far as I understand it, the B12 range varies according to location in the UK. It seems that each area sets its own range, maybe because that's what they think is roughly average or because the lower the range the less people need to be treated? In our location, 500 is tops but in some countries, 500 is considered bottom of range and 1000 - 1500 is considered more healthy. Could check with doc to put your mind at rest.

in reply to Nanaedake

thank you for taking the time to reply. I really appreciate any input. Having struggled with all of the issues of being hypothyroid over the years, I just think it unsettling that this was the result and I was told it was okay when there are issues with results that are too high. Probably doesn't make a lot of difference that I live in the U.S. — no matter where you are "out of range" is out ;') I will follow up just for peace of mind.

Serendipitious profile image
Serendipitious

Without ever supplementing my B12 was around 800. Then after taking B vitamins it rose to over 2000. Naturally my GP is concerned.

I'm not full of energy rather completely the opposite so I do think something isn't right. I've heard this could be due to a methylation issue but I've yet to test for the MTHFR gene defect. My Folate was also off the scale.

in reply to Serendipitious

I'm sorry I didn't reply to your post … somehow I missed it.

It's a puzzle isn't it? I too am not full of B12 energy that I often hear about. I hope you find a solution and feel better.

Nanaedake profile image
Nanaedake

Just to put your mind at rest, you could ask your doctor about your kidney status. If all ok then you'll feel much more relaxed.

in reply to Nanaedake

Thank you. I am due for a re-check soon and will be armed with lots of questions.

Hyburn profile image
Hyburn

I had high B12 result flagged up by Medichecks who recommended a full blood count and specifically to check liver and kidney function which all came back okay so will need to look into this more. Someone on here suggested checking out the pernicious anemia group.

in reply to Hyburn

Thank you for the helpful input. I have this question/request on my list of items for my next doctor visit. Much appreciated.

DizzLizzie profile image
DizzLizzie

Hi soozbee

I was just reading about your high B12 results you had 2 years ago, I too have a high reading 1044, wondered what you had found out after further investigations?

Regards

Dizzi

in reply to DizzLizzie

I’m sorry I have not. My doctor told me no worries and honestly I had forgotten about it. Thank you for the reminder I am going to a new doctor and will have him check my levels. I wish you the best with your findings.

Karispitit profile image
Karispitit

My B12 has come back at 1288 (I don't supplement) and GP and other doctors in practice are very concerned as they say its rare. I'm now having lots of blood tests done to find out cause. I have very high inflammation markers as well. They always ignore my thyroid disorder though.

Freebird3by3 profile image
Freebird3by3 in reply to Karispitit

Hi there, I was wondering did you ever find out what caused your high b12. Mine just came back 1876! Thanks for the help

in reply to Freebird3by3

Hello.

Sad to say that I did not find out. And the last time I had it taken which was in mid January it was down to

768 - so within range. 232-1245 pg/ml.

But my Vitamin D was just above the lowest range in January.

34.0 - 30-100 ng/ml

So I am supplementing with Vitamins D and K2

I have recently been diagnosed with Eagle Syndrome and that has kind of taken my attention away from everything else.

I hope you find out what’s going on with you.

Nancy_88 profile image
Nancy_88 in reply to

Nice how vitamin B12 got lower :))

Did this happen naturally or you followed any guidelines?

in reply to Nancy_88

It seems to have declined on its own. 🤷‍♀️and my thyroid levels seem to have settled down as well.

I have been taking Levothyroxine (generic) 125 mcg. And Liothyronine (generic) 5mcg. for awhile now and it’s the best I have felt regarding my thyroid issues in years.

Best with your health … 🙏

Shamrock40 profile image
Shamrock40 in reply to Freebird3by3

Hi, I've had very high B12 (unsupplemented) since first tested in 2014. I have seen a haematologist and had many blood tests for a range of conditions. All came back negative. It is a mystery and I am well. I read an article that it can be caused by small intestinal bacterial overgrowth. My doctor has stopped even checking my B12 levels, just the Full blood count,and Liver function mainly.

in reply to Shamrock40

Glad to hear you are well. I’m thinking that high level I had must have been a fluke.

Freebird3by3 profile image
Freebird3by3

Thanks so much for coming back to me! Will keep the thread posted

shortytlc profile image
shortytlc

Just wondering if any with high levels have you been drinking any energy drinks/foods ? I know the drinks can raisr levels

in reply to shortytlc

I am not an energy drink person at all. But I have really grown to ❤️ aloe juice and some type of citrus juice combo. I prefer at least 3/4 aloe juice to 1/4 orange/mango juice. I drink loads of it now. 😋

shortytlc profile image
shortytlc

Have a little read of aloe juice, it does contain b12 from what I could see. Could explain your higher levels.

helvella profile image
helvellaAdministratorThyroid UK in reply to shortytlc

Every time there is mention of a plant source of B12, it seems to be a mistaken understanding.

In this case:

It turns out that there have been a couple studies which show that aloe vera enhances the absorption of vitamin B12 for older people

jacknorrisrd.com/aloe-vera-...

Some plants do contains substances similar to B12. But most of these do not work as B12 in our bodies.

I agree wholeheartedly with this:

In my opinion, it is a fool’s errand to rely on anything but B12 supplements, or fortified foods for vitamin B12 on a vegan diet.

jacknorrisrd.com/aloe-vera-...

(Or known B12-containg foods such as meat, if not vegetarian/vegan.)

I am always sceptical about every claim for aloe vera. There is a gigantic marketing effort behind aloe vera products. Clearly, they are very profitable to some.

in reply to helvella

I’m sorry I missed this post. Loads of great information! Thank you 🙏

I started drinking aloe juice only because I find it refreshing when mixed with a bit of fruit juice … it is definitely an acquired taste because my husband makes this face (😝) when he tries even a small sip!

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