Hi ive had a blood test and my results show a normal free t4 and tsh of 4.51. It says the normal range of the tsh should be 0.35-5. Last year when I was tested it was 2.72 and 3 years before it was 2.0. My mum has had an overactive thyroid and has now had radioiodine treatment and my older sister has an underactive thyroid. I have also been feeling generally unwell for about a month and have put weight on and very difficult in losing any. Is it likely to keep rising and develop into underactive thyroid? And is 4.51 enough to be feeling symptomatic even though it's in normal range?