I remembered an occasional a few years ago whilst collecting my prescription from Boots. The pharmacist interviewed me as a matter of course. I advised her that I regularly forgot to take my hormone and meds. She suggested using a dosette box. Her advice was to take my 2 Codeine, 2 Omeprazol 100 Thyroxine 1 Calcichew all at once then refill the box. I said that I might be inclined to take them again later in the day as I am scatty. But the worst part now that you good people have educated me is that there wasn't a peep out of he regarding the correct way to take my Thyroxine.