I have been on Adrenaplex for the past few months, after successfully (and finally) managing to wean myself of Medrol (put on it in late 2011 after being diagnosed with adrenal fatigue by Hertoghe doctor).
Adrenaplex contains licorice root, and I know you are supposed to avoid that if you suffer from hypertension which I do (I have been on blood pressure medication and beta blockers since late 2011). Even after losing 20 kilograms/3.2 st I seem unable to get my systolic pressure below 140 as recommended (last night, BP was 151/76, resting pulse 88). I found this info on a site called Tired Thyroid, and am currently wondering if I should assume I am slightly overmedicated on NDT, or if licorice root could indeed be the culprit...Lab results from Dec 15 2016 indicated I was indeed overmedicated (FT3 4.6, ref 1.7-3.7), so I cut back 1 grain last week. I have currently no (other) symptoms of being overmedicated.
This is the information I found on Tired Thyroid:
If you are taking T3 in any form (desiccated thyroid or liothyronine like Cytomel), and your systolic BP is over 140 mm Hg while your diastolic number is less than 90 mm Hg, you may need to adjust/reduce your dose. A resting heart rate over 85 beats per minute also suggests overmedication, as does any form of arrhythmia (irregular heartbeat, especially atrial fibrillation).