Zinc carnosine & thyroid function: Hi I am still... - Thyroid UK

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Zinc carnosine & thyroid function


Hi I am still suffering with stomach acid problems related to prescription NSAID use (without being given a stomach protector) post surgery 2 years ago.

I have been managing with DGL liquorice supplements / Apple cider vinegar / sauerkraut / but it is gathering momentum again and making eating tricky.

I have been reading about zinc carnosine but the Mayo clinic website suggest a long list of cautions. Ace inhibitors - (I take a blood pressure med) and ir possibly altering thyroid function (I take thyroxine).

Does anyone have any experience of any alterations to their thyroid function? I'm really nervous as I have a terrifying ordeal last winter with a very bad Hashi flare.



5 Replies


I'm sorry you've had no response. Feel free to repost your question.

I took zinc carnosine for six weeks. That was all it needed to cure my gastritis. During that time I didn't notice any difference in my thyroid status, but I didn't test it of course. However, it didn't make any noticeable difference, and I am fairly tuned in to my thyroid status.

It really was a miracle cure for me, and although I hadn't come across that particular suggestion, knowing how well it works I would probably have risked it. You could maybe take your temperature while taking it if you are worried.

The problem with ACE inhibitors seems real though. So if you are on one (the data sheet should tell you if it is one) then maybe ask for a different medication?

in reply to Ruthi

thanks for your reply Ruthi, I appreciate the time taken to respond. I really want to take the zinc but I guess I must weigh it all up in the light of the other drugs I take.


I do think the risk is the ACE inhibitors. Once I started googling the thyroid/zinc carnosine connection lots of people are recommending it to thyroid patients to treat damage from low stomach acid.

Most of the discussions online are about zinc supplementation for patients on ACE inhibitors, because they bind to the zinc. So if you look at it the other way around, the zinc will bind to the ACE inhibitor rendering it less active. What I am not sure about is how strong that effect will be, and how quickly you would see a rise in blood pressure. If you are really keen it might be worth talking to your GP, and considering whether with careful monitoring the risk is worthwhile. There is also the possibility of taking your ACE inhibitor well away from the zinc carnosine.

Gastritis is not without risk itself - with the raised possibility of stomach cancer, and also the possibility of progression to an ulcer. So its all an exercise in risk management.

BTW, when I had gastritis fasting helped. At the time I didn't have the tools or health to do an extended fast, but that might also may also be something to consider.

I'm on the ACE inhibitor Ramipril, which I always took an hour or so after my thyroid treatment, until recently, when I found Felodipine severely interfered, so I started taking my morning pills four hours or so after. My TSH had been quite stable, though I was expecting an increase over the winter, so it came as quite a surprise to find it has dropped, which could also be due to biotin in a supplement I take. After reading around, I've decided to take the Ramipril at night, which I hope will improve its effectiveness.

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