Thanks scruby Well, you have a fair way to go with your TSH, that needs to be down to about 1 or below or wherever it needs to be for your FT4 (and FT3 if they will test it) to be in the upper part of their ranges. With that range for FT4 that would be about 16+ if that's where you feel well and symptoms subside.
Levo doesn't suit everyone but we have to give it time when starting, sometimes a starter dose does make us feel worse, so see how you go. You will most likely be increased to 75mcg daily next time, and so on until you are feeling better. Push for increases if you don't feel well, don't let your GP be guided by TSH alone. This might be helpful if you find you need some back up in the future:
Dr Toft, past president of the British Thyroid Association and leading endocrinologist, wrote this in a Pulse Online magazine article:
"The appropriate dose of levothyroxine is that which restores euthyroidism and serum TSH to the lower part of the reference range - 0.2-0.5mU/l.
In this case, free thyroxine is likely to be in the upper part of its reference range or even slightly elevated – 18-22pmol/l. Most patients will feel well in that circumstance.
But some need a higher dose of levothyroxine to suppress serum TSH and then the serum-free T4 concentration will be elevated at around 24-28pmol/l.
This 'exogenous subclinical hyperthyroidism' is not dangerous as long as serum T3 is unequivocally normal – that is, serum total around T3 1.7nmol/l (reference range 1.0-2.2nmol/l)."
If you email firstname.lastname@example.org she will let you have a copy of the article which you can print out and show your GP or Endo.