Disey Well, you don't seem to be doing very well on it do you
What was your dose of Levo in January before the change to 125mcg? Was it an increase or decrease? Whatever it was hasn't helped you one bit. Your TSH has risen and your FT4 is still very low in range.
Dr Toft, past president of the British Thyroid Association and leading endocrinologist, wrote this in a Pulse Online magazine article:
"The appropriate dose of levothyroxine is that which restores euthyroidism and serum TSH to the lower part of the reference range - 0.2-0.5mU/l.
In this case, free thyroxine is likely to be in the upper part of its reference range or even slightly elevated – 18-22pmol/l. Most patients will feel well in that circumstance.
But some need a higher dose of levothyroxine to suppress serum TSH and then the serum-free T4 concentration will be elevated at around 24-28pmol/l.
This 'exogenous subclinical hyperthyroidism' is not dangerous as long as serum T3 is unequivocally normal – that is, serum total around T3 1.7nmol/l (reference range 1.0-2.2nmol/l)."
If you email email@example.com she will let you have a copy of the article which you can print out and show your GP.
You need an increase in your Levo to get you where you need to be as far as FT4 and FT3 are concerned to alleviate your symptoms. Don't let your GP dose by TSH alone, which is what most of them seem to do. The TSH is irrelevant once we are on thyroid replacement.
It would be really useful if you could get the following tests done, in addition to TSH and FT4:
FT3 - this is the active hormone, T4 is the storage hormone and converts into T3 which does all the work, it is needed by every cell in the body and we need to know that we have enough T3.
TG antibodies (but NHS doesn't seem to do that one for some unknown reason)
The two antibody tests will tell you if you have positive thyroid antibodies which cause autoimmune thyroid disease aka Hashimoto's.
Also needed are:
These vitamins and minerals all need to be at optimal levels (not just in range) for thyroid hormone to work. They are very important.
If you can't get these tests done through your GP then get them done privately with a Blue Horizon Thyroid Plus Eleven test bluehorizonmedicals.co.uk/T... because it looks like you are going to need to start helping yourself.