Thyroid UK
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mood swings

Hi there , 

Please could someone tell me do they find that their mood changes from one day to the next depending on how tired and dizzy you feel . One day I can be feeling great and the next I cry or get angry for the least www thing and I'm finding that I am jealous of one of my friends who has amazing health and who does not understand my condition at all and constantly tells me I should try harder which sometimes is very difficult if you have no energy at all . I am on 25mg of t3 every day and take 75 mg of levothyroxine every other day . I'm not meaning to moan and I am so sorry if it sounds like this . Many thanks for taking the time to read this .

8 Replies

((Hugs)) I'm not sure I can offer advice but you're absolutely not alone. I know for sure it's impossible for me to stay happy, smiley and positive on the bad days! xx



It's very difficult not to have low moods when you feel unwell.  If you post results and ranges for thyroid, ferritin, vitamin D, B12 and folate members will advise whether you are optimally medicated and whether vitamin and mineral levels are good.

Healthy friends often don't get it that feeling exhausted and ill isn't something which can be cured by a more positive attitude and making more effort.


Hi Clutter , thanks so much for your kind reply . My results are still the same as my last post I can't get tested until I'm on the increased dose for six weeks and that will be in two weeks . No healthy people definitely do not undertstand as they think you are complaining too much or not making an effort lol. Thanks 


With hypo, we are dealing with hormones which have an effect on every part of our body from top to toe. That's why at times our emotions are upside down and can vary from anger to despair.

Maybe your dose isn't yet at an optimum and your dose seems unusual to me. 25mcg T3 daily (equal between 75 and 100mcg levo in its effect). Plus 75mcg levo every other day?


Hi Shaws ,  thank you so much for your kind reply . My moods are so up and down I don't recognise myself sometimes at all as I can be snappy at the least wee thing then happy then next minute sad . Do you think that's too strong of a dose ? My Endo said my t4 was too low and that's why he increased it from 50 mg every other day and 75mg alternate days . My iron is low too. Thanks 


What you need is an up-to-date blood test so it would give a fuller picture.

I don't know what your Endo means by 'my T4 was too low'!. If we take T3 as well as T4 our T4 will be lower.

These blood tests were introduced along with levothyroxine only, so I don't know what they're talking about when they mention T4 being lower when there has been an addition of T3 to the patients dose of levo. Talk about confusing the issue. The fact is that you still don't feel well that's the crux.


Hi Shaws  , I appreciate all your advice and help so much . My moods are so up and down just not myself at all . I think I should stop taking coffee . I am seeing a nutritionist on Tuesday so I'm hoping that will help . These are my results from over a month ago . T4 12.8 range 12-22 mg

T3 6.0 range 3.1-6.8

TSH0.02 range 0.27-4.2 

Thanks :) 


Coffee interferes with the uptake of hormones.

High cortisol can be eased with Vitamin C.

Maybe your Endo would let you trial T3 only (?). I only improved when I dropped T4. That's not to say everyone does. The fact the he is interested in your T4 as I said before he doesn't realise that T3 reduces T4. We are only talking here about what's in the blood - not what's in your cells and that is T3. We cannot test what is in our cells but a Free T3 and FT4 tell us what's circulating.

I am not medically qualified of course


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