Increase in Levothyroxine from 125 to 150 mcg

Sometimes our requirement for thyroxine does fluctuate. It is quite reasonable to assume you might need a small increase.

The normal range is usually around 0.3 to 4.5 or something similar so perhaps they meant 0.3 rather than 3.

Remember to make sure you are taking your thyroxine on an empty stomach with water only. You need to avoid taking certain other medications (such as antacids, PPIs, oestrogen containing pill etc) and supplements (particular calcium, magnesium and iron) at the same time. It is best to take your thyroxine an hour before or 4 hours after these other tablets. Absorption can be affected and this can play a big part in changes in your blood levels of thyroxine.

Sometimes some people find different brands of thyroxine are more effective than others, perhaps due to different absorption rates due to the different fillers used in them. This might also be contributing.

If your oestrogen levels have increased for any reason, this can cause and increase in the protein that binds to thyroxine which means you would have less thyroxine free and unbound in the blood. Common reasons for an increase in oestrogen are pregnancy, the contraceptive pill or HRT. Obviously these dont apply to men.

I hope that helps

Carolyn x