B12 joint pains

[Fuzb]

Hello - quick question, I've started B12 spray 1200mcg as my B12 was low and the last two days and started to get a few aches in my wrists and fingers on and off. Not had any aches before.

Is this normal?

Will they go away If I carry on?

Or should I start on one squirt and work up to four?

[Marz]

You are probably waking things up that have not been stimulated before as the B12 was low. B12 affects the myelin sheath protecting the nerves I believe....

[Clutter]

Fuzb, have you had vitamin D tested? It was vitamin D deficiency which caused joint pain in my hip and knee. I don't think it's likely that a low dose 1,200mcg would have much effect on myelin sheath as Marz, suggests. That sometimes happens when B12 deficient patients have 1mg loading injections.

[Fuzb in reply to Clutter]

My Vit D was at 45nmol two weeks ago and am on 3800IU now so should see that bump up on the next test, B12 was 92nmol (124pg/ml).

I think I'll take it slow this week with one spray a day then increase next week if that goes OK, might just be my body getting used to the vitamins it needs - certainly feel a bit perkier with the B12.

Thank you

[Clutter in reply to Fuzb]

Fuzb, that B12 result doesn't look right. It's usually expressed in ng/L followed by a ref range ie 725ng/L (190-900).

[Fuzb in reply to Clutter]

I am a bit confused too is it because it is active B12? - it says in full "Active B12 92 pmol/L 25.1 - 165.0"

Edit: just found this comparing total and active, looks like I have plenty and probably don't need to take it?

active-b12.com/Clinical-Uti...

[Clutter in reply to Fuzb]

Fuzb, Thats right Active B12 >35 is unlikely to be deficient.

[helvella Administrator in reply to Clutter]

A trap to fall into.

Serum vitamin B12 tests results are in pg/mL (picograms/millilitre) or pmol/L (picomoles/litre). The laboratory reference ranges for these units are similar, since the molecular weight of B12 is approximately 1000, the difference between mL and L. Thus: 550 pg/mL = 400 pmol/L.

en.wikipedia.org/wiki/Vitam...

When we see results from around the world, we need to be sure which units are being used. The difference is, numerically, modest, but could make a substantial difference to interpretation. Of course, pg/mL is identical to ng/L

[Clutter in reply to helvella]

Rod, I fell into to the pg/ml, ng/L, pmol/L trap but was also confused by the result and what appeared to be a partial range "B12 was 92nmol (124pg/ml)" given. Fuzb has corrected it

[Spareribs]

Fuzb - vitamin D (a secosteriod/sunshine) often underpins other deficiencies.

e.g a colleague at work's mum was told B12 wouldn't work if D3 was low. A classic symptom is painful shins (& rickets in children).

Low iron also causes pain, and low Thyroid function itself (see Dr Lowe). J