B12 joint pains: Hello - quick question, I've... - Thyroid UK

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B12 joint pains

Fuzb profile image
Fuzb
9 Replies

Hello - quick question, I've started B12 spray 1200mcg as my B12 was low and the last two days and started to get a few aches in my wrists and fingers on and off. Not had any aches before.

Is this normal?

Will they go away If I carry on?

Or should I start on one squirt and work up to four?

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Fuzb
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9 Replies
Marz profile image
Marz

You are probably waking things up that have not been stimulated before as the B12 was low. B12 affects the myelin sheath protecting the nerves I believe....

Clutter profile image
Clutter

Fuzb, have you had vitamin D tested? It was vitamin D deficiency which caused joint pain in my hip and knee. I don't think it's likely that a low dose 1,200mcg would have much effect on myelin sheath as Marz, suggests. That sometimes happens when B12 deficient patients have 1mg loading injections.

Fuzb profile image
Fuzb in reply to Clutter

My Vit D was at 45nmol two weeks ago and am on 3800IU now so should see that bump up on the next test, B12 was 92nmol (124pg/ml).

I think I'll take it slow this week with one spray a day then increase next week if that goes OK, might just be my body getting used to the vitamins it needs - certainly feel a bit perkier with the B12.

Thank you

Clutter profile image
Clutter in reply to Fuzb

Fuzb, that B12 result doesn't look right. It's usually expressed in ng/L followed by a ref range ie 725ng/L (190-900).

Fuzb profile image
Fuzb in reply to Clutter

I am a bit confused too is it because it is active B12? - it says in full "Active B12 92 pmol/L 25.1 - 165.0"

Edit: just found this comparing total and active, looks like I have plenty and probably don't need to take it?

active-b12.com/Clinical-Uti...

Clutter profile image
Clutter in reply to Fuzb

Fuzb, Thats right Active B12 >35 is unlikely to be deficient.

helvella profile image
helvellaAdministratorThyroid UK in reply to Clutter

A trap to fall into. :-)

Serum vitamin B12 tests results are in pg/mL (picograms/millilitre) or pmol/L (picomoles/litre). The laboratory reference ranges for these units are similar, since the molecular weight of B12 is approximately 1000, the difference between mL and L. Thus: 550 pg/mL = 400 pmol/L.

en.wikipedia.org/wiki/Vitam...

When we see results from around the world, we need to be sure which units are being used. The difference is, numerically, modest, but could make a substantial difference to interpretation. Of course, pg/mL is identical to ng/L

Clutter profile image
Clutter in reply to helvella

Rod, I fell into to the pg/ml, ng/L, pmol/L trap but was also confused by the result and what appeared to be a partial range "B12 was 92nmol (124pg/ml)" given. Fuzb has corrected it :)

Spareribs profile image
Spareribs

Fuzb - vitamin D (a secosteriod/sunshine) often underpins other deficiencies.

e.g a colleague at work's mum was told B12 wouldn't work if D3 was low. A classic symptom is painful shins (& rickets in children).

Low iron also causes pain, and low Thyroid function itself (see Dr Lowe). J :D

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