When testing B12 should we rely on the b12 bloo... - Thyroid UK

Thyroid UK

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When testing B12 should we rely on the b12 blood serum result? Or the active b12 result?

4 Replies

Could anyone clarify this?

I had a series of b12 injections about 4 months ago.

Recently my Active b12 was tested.

The result was 200 which is above range. Presumably this is good???

But I did not have my Serum b12 tested?

Any thoughts?

Thanks

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4 Replies
Hypopotamus profile image
Hypopotamus

Thank your lucky stars! I am still trying to convince the morons that I need my active B12 levels tested while they tell me that my serum levels are normal. Active levels are the ones you need to know but it's how you feel that should really count. If you are tired again then you need another injection.

Heloise profile image
Heloise

There are some questions regarding B12 testing. Some MS sufferers are found really to have a B12 deficiency. I don't know about the active test but STTM says this:

B-12 lab test: Measures an essential vitamin, B12, which can be low in hypothyroid patients due to low stomach acid. You are looking for an optimal B12 lab result in the upper part of the range, such as the upper quarter at least. It is NOT optimal to simply be “in range”. For example, if your range is similar to 180-900, a healthy level appears to be 800 or higher. In the 500-800 range, you can benefit from taking B12 lozenges, specifically Methylcobalamin. It has been shown in studies that patients with labs under 350 are likely to have symptoms, which means the deficiency is very serious and has gone on for a few years undetected. Lab ranges are much too low for B12…in Japan the bottom of the range is 500. The urine test Urinary Methylmalonic Acid, also called the UMMA, can be added since it is a very sensitive detection and if high, will reveal a true B12 deficiency.

shaws profile image
shawsAdministrator

The Active B12 is the most up-to-date and much more accurate than the serum test. this is a link:

healthunlocked.com/thyroidu....

Marz profile image
Marz

How long after B12 treatment did you have the Active B12 test ? There needs to be a gap I believe....

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