Does anyone have any experience of taking low dose naltrexone, desiccated thyroid, and metformin all together. I have gluten intolerance, rheumatoid arthritis, very low basal temperature (lowest was 34.9, averages around 35.3) , probable adrenal problems if the standing / sitting blood pressure test is anything to go by, and I am finding it impossible to lose weight . GP predictably says I am completely healthy. I have started taking ldn, which I think is helping the RA, but is not helping with the weight. Anybody any advice for me before I go and try and find a private doctor to have a conversion with??