Hi Im due to see specialist again next week...my second appt after wasting 4 yrs with GP. At my last app my TSH was 10 and TPO of 1875 and Free T4 of 14. The specialist increased my levothyroxine to 100mcg from 75mcg and told me my GP should have increased the dosage as soon as he'd seen these levels (4months previously) since the increase I don't feel much better in myself but my knees don't ache so much and I still get breathless sometimes. My biggest problems are fatigue and weight gain which I just cannot shift (1 and a half stone) .even after going to the gym 3 times a week for 6 months. My question is, will he just increase my tablets another 25mcg? This has been going on for over 4 years and Im really fed up with how long it's taking to get the levels right. Will I ever lose this excess weight?! It may not sound like much but Im only5 feet 2 and its not a weight I am comfortable at. plus the fatigue, I wake up feeling alright for a bit then a few hours later feel like Ive not been to bed.