Just read some research that taking Raloxifene with Levo is a no no - ( drug interaction renders Levo useless as it can't be absorbed in presence of Raloxifene) . I am very concerned as I have been on both for years - and have gained 2 stone - my TSH was 3 (on 100mcg Levo) but Labs refusing GP request to do t3/t4 .Since having hypo symptoms my new GP raised it to 125 mcg and I feel better but weight won't shift - even though I have cut out gluten and sweet stuff. Labs refusing GP request to do t3/t4 - so where do I go from here? Both my parents have Hashi's so wondering if Gene D102 test might help to detemine if its a Evista /Levo problem or genetic - and if gene test is positive - can I insist on t3 therapy ? Hope someone has suggestions as I am DESPERATE to lose this weight.!!