Hi all,
This is my first question though I've been reading a lot on here the past few weeks. I wish I'd joined sooner- it would have really altered my decisions this past year..
I found I was really tired last year so after some thinking asked my doctor to do a thyroid check and came up with a TSH of 4.5 (0.3-3), low normal free T4. Positive antibodies so managed to persuade my doctor to trial me on levothyroxine. Some hiccups along the way but I'm currently on 150mcg a day, hoping it's the right dose!! Just moved up from 100mcg, TSH 2 weeks ago was 4.0.
Anyhow, earlier this year I also found I was vit D deficient and my ferritin is always scraping along the bottom of the reference range. Trying to manage these myself, I requested copies do all my bloods and noticed my total B12 had fallen from 450 to 312 over 6 months. Docs didn't seem concerned so I had an active B12 test done by Blue Horizon. The result was 56.7pmol/L (25-125). At the time, I read something that said 25-50 was the grey zone where further investigation might be done so didn't pursue anything because I was above this.
However, I've since read that anything less than 70pmol/L should be investigated. Unfortunately, I've been taking sublingual b12 10000mcg daily for the past few months. I can't bear the thought of stopping them as I'm just about getting by at the moment. I would really like to know, though, if it's PA or just deficiency. Would antibody testing be worthwhile at this stage?? I know the treatment is the same but I also know PA sufferers are at increases risk of gastric cancer so would like to have the correct monitoring in the future. It would also be good to know if this is a for life thing or whether I could scale supplements back. I'm taking something like 15 tablets a day at the moment for everything; it would be good to cut back!!
Sorry this is so long-winded; I just wanted to include what I thought was relevant.
Many thanks in advance