I have been taking thyroxine for 21 years now, and for a number of years I have also been taking Omprizole for gastric reflux. I take the thyoxine first thing in the morning, and the other one mid afternoon. I have just had to change the Omprizole because I have CMT1A and Omprizole can,apparently, make progression of the disease quicker. I was advised by others on a CMT group on Facebook to change medication, so spoke to a doctor who has now prescribed Rabeprazole instead, which is supposed to be okay for those with CMT (periperal neuropathy). I have just read the instruction leaflet for the Rabeprazole, and it states to take the tablet first thing in the morning before eating or drinking anything. Can anyone advise me please?