When I first started on levothyroxine in August last year I went on holiday to Crete about 2 weeks later. My ankles blew up straight away when normally this doesn't happen until half way through the 2nd week and then about 3 days into the holiday I went in the sun for about half an hour and started vomiting and going really cold. This lasted about a day but I was still unwell for about 2 to 3 days and it seemed I had suffered due to the heat. Going to Crete again this summer and wondering whether to just stay in the shade for 2 weeks. Have never had this happen to me before abroad and could only think the difference was my new medication. Anybody got any ideas about this?