Eltroxin variations.: I was originally prescribed... - Thyroid UK

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Eltroxin variations.

trig profile image
trig
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I was originally prescribed the 'old' Eltroxin when it was manufactured by Smith Kline I believe. Years ago my GP switched me on to levothyroxine which didn't really suit me. I asked to go back on Eltroxin but was told that it was the same under a different name and more expensive. I stayed on these tablets for years until visiting NZ to see my son who is also on replacement thyroxine. He was prescribed Eltroxin and I obtained a prescription. The NZ Eltroxin tablets came in a bottle, not bubble wrapped and are fatter than my UK tablets. They suited me much better, just as they had years ago. I came back to the UK and asked my GP to prescribe Eltroxin and acquired Goldshield Eltroxin 100 microgram bubble wrapped tablets which appear identical to the Levothyxine tablets produced by Mercury Pharma (and indeed appear to be manufactured on the same premises). Question : What has happened to the different Eltroxin tablets currently available in NZ and formerly available in UK (fatter tablets sold in bottles, rather than bubble packs). They were clearly much better for me than what is currently being offered by Goldshield/Mercury Pharma. Where can I get them in the UK ?

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trig
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RedApple profile image
RedAppleAdministrator

The levothyroxine tablets you refer to are not obtainable in the UK. Levothyroxine currently available in the UK is detailed on our main website page here:

thyroiduk.org.uk/tuk/treatm...

That said, levothyroxine in the Eltroxin branded packaging is currently in short supply. See the news item about this here:

thyroiduk.org.uk/tuk/news.h...

.

trig profile image
trig

Thanks RedApple, I have some 'Eltroxin' recently acquired in UK produced by Goldshield. These tablets are not the same as the Eltroxin tablets I acquired in NZ in March 2013 which were fatter, sold in a bottle and very similar to the original UK Eltroxin tablets I was prescribed 20 years ago. The fatter original NZ Eltroxin seemed to suit me far better than what is currently being offered in the UK. Definitely a different tablet with a much better effect. Where can I get them ? (other than trying to purchase them from NZ)

when I first started on thyroxine 10 years ago my tablets were always dispensed loose in a bottle. At some point they appeared in blister packs, and I was told this was an EU regulation i.e. tablets could no longer be dispensed loose.

in reply to

Levothroxine is still available in large tubs but there's been a general move to using blister packs of 28.

helvella profile image
helvellaAdministratorThyroid UK

I do not know the details of the Smith Kline era or quite how things ended up as they are.

The formulation of Eltroxin varies between that produced for Amdipharm Mercury (formerly Goldshield) in the UK, that produced by GSK, Aspen and various other products around the world where “Eltroxin” is not a protected name. The differences are considerable.

(I think that a few years ago Aspen picked up rest-of-the-world-wide rights to former GSK Eltroxin while GSK retained north America.)

A few years ago there was a major problem with Eltroxin in New Zealand. This seemed to occur after production was transferred from north America to Germany. (For a while both GSK and Goldshield Eltroxin were both available in New Zealand.)

(Similar types of problem have also occurred in Denmark and Israel.)

The UK’s MHRA produced a report on the issue:

medsafe.govt.nz/hot/MHRA%20...

When it comes to UK versions of levothyroxine, you are quite right that our Eltroxin is identical to Mercury Pharma Levothyoxine.

thyroiduk.healthunlocked.co...

So, in answer to your question, GSK Eltroxin is available in north America, Aspen Eltroxin is available in a number of other countries around the world, and other variations of Eltroxin are also available. Your chances of getting any of them prescribed in the UK at all are not good, and on the NHS probably close to zero. It is possible that a specials company like IDIS could get them for a pharmacy on your behalf, once a prescription has been obtained! So you end up with internet purchase options as possibly being the easiest. Be careful.

Rod

in reply to helvella

>Your chances of getting any of them prescribed in the UK at all are not good, and on the NHS probably close to zero.

I agree. The doctor would not simply be able to prescribe Eltroxin. There is no possibility that a pharmacy could import from NZ in this case. It would not be legal and the pharmacy would not be able to claim back the substantial costs which would be incurred in obtaining the product.

The doctor would need to hand write a prescription to the effect of 'Eltroxin tablets (manufactured by GSK) to be imported from New Zealand as an unlicensed medicine on a named-patient basis' and then all the usual details like strength, dose and quantity.

>It is possible that a specials company like IDIS could get them for a pharmacy on your behalf, once a prescription has been obtained!

It's possible, but they might not have had such as request before. I suspect that it would take some time to obtain.

Most GPs would not agree to this.

helvella profile image
helvellaAdministratorThyroid UK in reply to

Just to make it even more confusing, the version now sold in New Zealand seems to be from Aspen (not GSK).

eltroxin.co.nz/

Obviously that looks like it conforms to the GSK world-wide-except-north-America sell off.

Rod

in reply to helvella

I must admin I didn't check. In that case they'd need to write Aspen!

GSK have sold quite a few of their old products to Aspen.

cein profile image
cein in reply to helvella

I looked on the GSK web site and it said they now only manufacture and sell for Canadian market :-(

cein profile image
cein in reply to cein

Sorry might have got that wrong it could be North America.

trig profile image
trig

Thank you Jan, Its very confusing and I have learned a lot from the NZ Medsafe site. It seems that Glaxo Smith Kline changed their formulation in 2007 and introduced it in NZ with some mixed results. That is the tablet I recently used in NZ and found it to be very good but it doesn't appear to be available here in UK.

trig profile image
trig

Many thanks Rod, Doctors I have spoken to in both UK and NZ have confirmed concerns about the variation in performance of the the various thyroxine tablets. I note your word of caution, thanks. Terry

helvella profile image
helvellaAdministratorThyroid UK in reply to trig

If you use the blue "Reply to this" below someone's response, then they get an alert email when you respond, and your response gets indented to make things clearer.

Don't worry everyone seems to make this mistake at first. :-)

trig profile image
trig in reply to helvella

Many thanks

helvella profile image
helvellaAdministratorThyroid UK in reply to trig

:-)

It works.

cein profile image
cein

If you find out where you can get them can you PLEASE let me know ...... 13 yrs I have been looking for the same info as you ..... I was taking the Glaxo brand Eltroxin in S Africa and my health has been on a downward spiral since coming back to UK.

Apparently the Gold Shield Eltroxin brand has now been sold and is being manufactured by Mercury Pharma.

helvella profile image
helvellaAdministratorThyroid UK in reply to cein

GSK Eltroxin can be found on the internet.

Aspen Eltroxin (which might or might not be the same or work the same for you) can be found on the internet.

However, it is obviously difficult to be sure what you are getting as there are so many scams as well. One version, for example, is made in India. That does necessarily mean anything is wrong with it - might be exactly what you want. But very difficult to know. It says it is GSK Eltroxin to the old formula!

Goldshield renamed themselves to Mercury Pharma. Then the company which came to own them merged them with another company create the Amdipharm Mercury we now have! Was not so much a selling of brand name as whole company!

cein profile image
cein in reply to helvella

Thanks Rod ... Ohhh I don't know ... after watching a programme on TV last week where it showed drugs being made in India for the black market I think I will pass :-) haha Think I will ask Endo if I can try something else instead of Eltroxin.

helvella profile image
helvellaAdministratorThyroid UK in reply to cein

On the other hand, some of our standard medicines are made there!

I think Dr Reddy branded products are often made in India.

Rod

cein profile image
cein

Oh ok I didnt know that ..

I haven't heard of Dr Reddy as I have never taken any other drugs other than Eltroxin and Premarin which are taken every day and .. Fexofenadine in summer as I am allergic to all English and S African mixed grass including black,blue and green Burmuda, rape seed and wheat flower / flour ?

Get over SAD in winter and into allergies in summer .. I can't win.

I did think after I had written the comment that maybe I'm being a bit unfair and its me and not the Eltroxin .. whichever way I haven't been right since I had to change brands , coincidence I dont know ....

I don't care what they give me or what I take as long as I get my energy back and the pain goes away ... as long as it makes me feel human again ;-) :-)

Lynn

truthseeker136 profile image
truthseeker136

I have terrible brain fog from recently having to switch from T3 to T4. I used to take close to 200 mcg of T3 with no ill-effects. Now I can't get T3 and switch to Euthyrox made by Merck. I believe I have access to Eltroxin made by Aspen but the pharmacist steered me to the former. Is Eltroxin better?

Also can anyone help me with the dosing, I am not able to think straight and am kind of on my own with this because my doc isnt helpful

helvella profile image
helvellaAdministratorThyroid UK in reply to truthseeker136

When it comes to the different makes of levothyroxine, some stand out as being often preferred, others as being often disliked, but there is no overall consistency. We are all different and what is good for one might not be good for another.

I am in no position to judge between Aspen Eltroxin and Merck Euthyrox but I'd have to suggest that Euthyrox has probably had more positive comments (as a proportion) over the years.

If you really needed that T3, then no amount of levothyroxine, of any make, is going to be as good for you.

truthseeker136 profile image
truthseeker136

I'm given to understand that I have good conversion but dont make T4. Also had my reverse T3 checked before I started thyroid meds and no problems with that either. Should be fine.

Hasn't Euthyrox been in the news lately about some new reformulation causing patients to have problems. I think it was in France. I checked my ingredients list and it has the ingredient

truthseeker136 profile image
truthseeker136

Helvella,

Can you give me some guidelines as to the dosage? I can't seem to figure out what dose of T4 corresponds to every 100 mcg dose of T3.

I am trying to see if I can get some NDT. This whole process of switching is making my head spin, quite literally

helvella profile image
helvellaAdministratorThyroid UK in reply to truthseeker136

I have many times said that there simply is no reliable conversion factor. It depends on you.

We see everything from T3 being twice as potent as T4 through to ten times. Which would equate to 400 to 2000 micrograms of levothyroxine - which is crazy level dosing.

You don't say why you were on T3? And at a pretty large dose.

truthseeker136 profile image
truthseeker136

I was on T3 therapy based on BP and heart rate. Essentially my doc found my dose by using BP and pulse as indicators. So my dose was the highest that could be tolerated as indicated above and symptoms elimination. This doctor went only by that. I don't know how my body will respond now on t4 or how to find a comparative dose. I stopped t3 because I can no longer purchase it where I am.

truthseeker136 profile image
truthseeker136

I am having terrible side effects/symptoms on 200 mcg of Euthyrox since switching from t3. My abdomen is distended, looks like I swallowed a football. Cannot walk, so tired and swollen. Foggy thinking, feeling spaced out. Pain in the small of my back and muscle cramps all over. Is this my body reacting badly to the T4. Can anyone please shed some light? Wondering if I should try another brand (Eltroxin by Aspen)

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