prucalopride - Tips

[Hopetobewell]

Hi

Have been suffering with chronic constipation for that last 2 years, plus pain in the pelvic floor area & rectum. Mixture of pressure & burning pain. My NHS Gastro & physio appointments are currently 3/4mths apart so if I make any kind of improvement it is diminished by the time I get back to them as a new symptom has occurred. Anyway for the last 8mths have had very big bowel movements in the morning, followed by pain all day. (High Fibre diet & Magnesium citrate at night). 3mths ago this stopped and now back to Chronic constipation. My Gastro has put me on Prucalopride 2mg which I currently take each night. Have been on this a week. Bowel movements are now really super soft. Lots of narrow stools and leakage late in the day. Any tips on the best time to take this, dosage, do I need to reduce fibre. Also long term effects. So desperate for something to work that I didn’t ask enough questions. Next appointment with Gastro is now 7ths time.

[Bluemon75]

I take prucralopride in the morning, but I don't think it matters the time you take. It doesn't give me the effect that you say, but what you describe it happens to me if a take laxido or movicol. Have you stopped taking the other laxatives? Maybe you are taking too much fiber and should reduce it. I also have chronic constipation and unfortunately can't tolerate high fiber diet. It might be worth contacting your gastro consultant...

[Hopetobewell in reply to Bluemon75]

Hi

Thanks so much for replying to me. I have stopped taking the other laxatives. I do have flaxseed & chia in the morning. I will take your tip & see if reducing some of my fibre works. I will get on to the Gastro. Can I ask are you on 1mg or 2mg of Prucalopride how long have you been taking it for can I ask?

[Bluemon75 in reply to Hopetobewell]

I am on 2 mg of Prucralopride, I've been on it for 5 weeks now....

[Gizmo6]

I'm the same with constipation its been on and off for years, mostly on. I now have some tension in my perineum. I'm waiting on a gyne appointment but I believe years of constipation has caused this. I'm now making sure I include pelvic exercise in my regular exercise routines. If I'd of known years ago I'd of got more help. I've tried all laxatives over years nothing has really worked for me. I'm not too great on too much fibre. I'm currently taking flaxseed oil suppliments. I read they can have a mild laxative effect. I'm only on my first week. Maybe a coincidence as never tell with ibs but last few days I've been regular so time will tell. If you're struggling maybe ring your Gastro doc up for advice.

[Hopetobewell in reply to Gizmo6]

Thanks will get in contact with the Gastro

[Justbreathe55]

Hi I take 2mg at night I've been on them for a couple of years now, your body might just need time to adjust to them. I would definitely try and cut down on fibre for a while and see how you go. I'm having to take stool softeners with them atm which has caused the same issue as yours, but its only because of severe side effects from chemotherapy. Hopefully when I'm finished I can go back to just procolapride as they've been a god send for me. Good luck x