I'm just doing a bit of research on Alosetron. I searched on here, but no posts came up.
Is this not a common drug to treat IBS-D?
Do GP's in the UK not offer it.
I've been on a few tricyclic antidepressants but I don't get any benefits from them. Mirtazapine was helpful, but the weight gain was brutal.
I hear it works by slowing down the movement of stools through the bowel, thereby reducing diarrhea. If you're struggling with stress management this blog might be a big help! casadesante.com/blogs/diges...
I have done research into IBS and in my notes I identified the following regarding Alosetron (it appears not to be available in the UK due to adverse effects):
– has been shown to improve abdominal pain, discomfort, and bloating in female IBS-D patients
– careful prescribing of 0.5 mg BID helps avoid serious side effects of the drug including severe constipation and ischemic colitis: ncbi.nlm.nih.gov/pmc/articl...
– Alosetron is not available in the UK – it was withdrawn because of severe constipation (in 25% of people taking alonsetron) :
nice.org.uk/guidance/cg61/r...
– Reviews:
Have you tried any probiotics such as Alflorex for your IBS-D. This one has been scientifically studied for IBS.
I'm currently on hold waiting to get a GP appointment. Had yellow water poo for 3 days now. Never had that before.
I do take probiotics but not regularly I admit. I haven't seen any benefit from Bio Kult in the past. I have Gut Mate and Symbiotics.
I've taken some Enterosgel 2 hours ago for the first time. Not helping.
Oh dear. That's not good.
I have tried many probiotics over the years, but Alflorex worked best for me.
You may want to ask your GP for a test for BAM (bile acid malabsorption). This is a different condition to IBS with similar symptoms.
However, for IBS, the normal route is to try something like Alflorex first. This really needs to be trialled every day for 3 months. Precision Biotics, the manufacturer, have a support line so they can help you through the process. Failing that a dietician referral to take you through the FODMAP elimination and reintroduction diet. If neither of those help at all, you could be talking about BAM.
Still on hold... I did think that was a possibility. Also some kind of food poisoning maybe? Hope I don't get fobbed off with wait and see.
Just to update. Doc said I have gastroenteritis. I'm not too sure about that, as I don't have any vomiting or fever, and my stomach cramps aren't very painful. He said I have to give it a week, take Diaoralyte and if no improvement he will to a poo test on Monday.
Anyway, day 4 now. Took 2 doses of Enterosgel yesterday (gag) and todays poop was a bit better than water.
berberine with meals is good for firming up stools and also an antibacterial so it is good at removing harmful bacteria in the gut. I would try that in any case and helps with weight loss by making sugar up and downs less bad. Take with a B1 supplement if dealing with anxiety.
500mg of the Berberine?
I do take a multi i get sent from the US. It has 25mg of Thamine HCI in it.
Emetophobia & Colonoscopy. 
Hi - have just joined. Looking at symptons leads me to believe I MIGHT have IBS. 
IBS-C with chronic constipation and abdominal pain at night. 
How Can I fully evacuate my Bowels?
should I go to the ER
