I'm just doing a bit of research on Alosetron. I searched on here, but no posts came up.
Is this not a common drug to treat IBS-D?
Do GP's in the UK not offer it.
I've been on a few tricyclic antidepressants but I don't get any benefits from them. Mirtazapine was helpful, but the weight gain was brutal.
I hear it works by slowing down the movement of stools through the bowel, thereby reducing diarrhea. If you're struggling with stress management this blog might be a big help! casadesante.com/blogs/diges...
I have done research into IBS and in my notes I identified the following regarding Alosetron (it appears not to be available in the UK due to adverse effects):
– has been shown to improve abdominal pain, discomfort, and bloating in female IBS-D patients
– careful prescribing of 0.5 mg BID helps avoid serious side effects of the drug including severe constipation and ischemic colitis: ncbi.nlm.nih.gov/pmc/articl...
– Alosetron is not available in the UK – it was withdrawn because of severe constipation (in 25% of people taking alonsetron) :
nice.org.uk/guidance/cg61/r...
– Reviews:
Have you tried any probiotics such as Alflorex for your IBS-D. This one has been scientifically studied for IBS.
I'm currently on hold waiting to get a GP appointment. Had yellow water poo for 3 days now. Never had that before.
I do take probiotics but not regularly I admit. I haven't seen any benefit from Bio Kult in the past. I have Gut Mate and Symbiotics.
I've taken some Enterosgel 2 hours ago for the first time. Not helping.
Oh dear. That's not good.
I have tried many probiotics over the years, but Alflorex worked best for me.
You may want to ask your GP for a test for BAM (bile acid malabsorption). This is a different condition to IBS with similar symptoms.
However, for IBS, the normal route is to try something like Alflorex first. This really needs to be trialled every day for 3 months. Precision Biotics, the manufacturer, have a support line so they can help you through the process. Failing that a dietician referral to take you through the FODMAP elimination and reintroduction diet. If neither of those help at all, you could be talking about BAM.
Still on hold... I did think that was a possibility. Also some kind of food poisoning maybe? Hope I don't get fobbed off with wait and see.
Just to update. Doc said I have gastroenteritis. I'm not too sure about that, as I don't have any vomiting or fever, and my stomach cramps aren't very painful. He said I have to give it a week, take Diaoralyte and if no improvement he will to a poo test on Monday.
Anyway, day 4 now. Took 2 doses of Enterosgel yesterday (gag) and todays poop was a bit better than water.
berberine with meals is good for firming up stools and also an antibacterial so it is good at removing harmful bacteria in the gut. I would try that in any case and helps with weight loss by making sugar up and downs less bad. Take with a B1 supplement if dealing with anxiety.
500mg of the Berberine?
I do take a multi i get sent from the US. It has 25mg of Thamine HCI in it.
So difficult to pin it down
Can anyone help me
Looking for advice
Eating fats and diarrhoea. Is there a link here? Bile salt malabsorption?
Food Poisining 
