Hi I haven't wrote a post for sometime.Ive had IBS for 12yrs but over the last about 4yrs it has become chronic,now I've tried the Fodmap diet to no avail plus lots of medication. Now my question being is I was put on Mirtazapine for IBS which I've been on for 4yrs,I've decided to tapper off it as I feel it's medication that's doing no good. I feel the pain is getting worse would anyone know if coming off Mirtazapine is causing me to have stronger pain? The reason for coming off it is I thought it was doing no good after 4yrs plus I am on such a lot of medication for other more serious problems. I hope someone can help as it is getting unbearable. Sorry to go on so long.