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Vanishing White Matter (VWM) disease
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Aside from easing motor symptoms of Parkinson’s disease, deep brain stimulation (DBS) may also slow disease progression
https://parkinsonsnewstoday.com/news/dbs-reduces-toxic-clumping-parkinsons-rat-brain-cells-study/
https://parkinsonsnewstoday.com/news/dbs-reduces-toxic-clumping-parkinsons-rat-brain-cells-study/
Farooqji
in
Cure Parkinson's
3 months ago
FDA grants RMAT status for BlueRock’s Parkinson’s therapy
Good Morning or Evening All, Is this another "Teaser"or could this be ready and available for patients in the near future ? Food and Drug Administration (FDA) has granted a regenerative medicine advanced therapy (RMAT) designation for BlueRock Therapeutics’ investigational cell therapy
Bemdaneprocel
Good Morning or Evening All, Is this another "Teaser"or could this be ready and available for patients in the near future ? Food and Drug Administration (FDA) has granted a regenerative medicine advanced therapy (RMAT) designation for BlueRock Therapeutics’ investigational cell therapy
Bemdaneprocel
Baron1
in
Cure Parkinson's
3 months ago
pain in left side
Hi have Chorrosis of the liver and have been good up until today. I have felt discomfort in my left side and it goes up the left side of my back to my neck. I did contact my local gp who is going to do bloods on Tuesday as there extremely busy. Will it have something to do with my diagnosis? Or anyone
Hi have Chorrosis of the liver and have been good up until today. I have felt discomfort in my left side and it goes up the left side of my back to my neck. I did contact my local gp who is going to do bloods on Tuesday as there extremely busy. Will it have something to do with my diagnosis? Or anyone
Meanies
in
British Liver Trust
3 months ago
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Nicotine…… a complete no-brainer.
Update most don’t know about nicotine, you should. Read my previous post if you’re wondering about it. I’ll soon be off c/l. I have experimented with nicotine and it seems to work better than the meds. My sense of smell is returning. I’m smelling things that I wish I couldn’t smell, lol. I forgotten
Update most don’t know about nicotine, you should. Read my previous post if you’re wondering about it. I’ll soon be off c/l. I have experimented with nicotine and it seems to work better than the meds. My sense of smell is returning. I’m smelling things that I wish I couldn’t smell, lol. I forgotten
38yroldmale
in
Cure Parkinson's
3 months ago
Perineural invasion increases soft tissue progression risk in metastatic castration-resistant prostate cancer post-abiraterone resistance
Background : Prostate cancer presents with soft tissue progression (STP) is highly aggressive. We analyzed the risk factor for STP in patients with metastatic castration-resistant prostate cancer (mCRPC) who developed abiraterone acetate (AA) resistance. Methods : This retrospective study included
Background : Prostate cancer presents with soft tissue progression (STP) is highly aggressive. We analyzed the risk factor for STP in patients with metastatic castration-resistant prostate cancer (mCRPC) who developed abiraterone acetate (AA) resistance. Methods : This retrospective study included
God_Loves_Me
in
Advanced Prostate Cancer
3 months ago
FDA clearance for SYNC-T SV-102, a pioneering combo immunotherapy for Metastatic Castrate-Resistant Prostate Cancer
Source link: https://finance.yahoo.com/news/syncromune-inc-announces-fda-clearance-232200345.html SYNC-T SV-102 Therapy combines partial tumor oncolysis with a fixed-dose combination multi-target biologic drug to provide a novel, personalized therapeutic approach for the treatment of metastatic
Source link: https://finance.yahoo.com/news/syncromune-inc-announces-fda-clearance-232200345.html SYNC-T SV-102 Therapy combines partial tumor oncolysis with a fixed-dose combination multi-target biologic drug to provide a novel, personalized therapeutic approach for the treatment of metastatic
God_Loves_Me
in
Advanced Prostate Cancer
3 months ago
worries
Here again. I am just so worried still. My liver enzymes were high. Managed to stay off the booze. Alt gone down slightly but ggt gone up a lot. Iron is low. My g p keeps saying it’s mental health issues but surely that cannot make my bloods deranged. She did an e consult to hepology and he said I
Here again. I am just so worried still. My liver enzymes were high. Managed to stay off the booze. Alt gone down slightly but ggt gone up a lot. Iron is low. My g p keeps saying it’s mental health issues but surely that cannot make my bloods deranged. She did an e consult to hepology and he said I
Curryblue
in
British Liver Trust
3 months ago
What happens next
My 68 year old husband was diagnosed with metastatic prostate cancer to the bones Oct 22 with PSA at 220. Since then he has been on Zoladex, Enzalutamide and has just finished 8 rounds of Docetaxel. Apart from this cancer he is very healthy - but what happens now when the PSA starts rising again. He
My 68 year old husband was diagnosed with metastatic prostate cancer to the bones Oct 22 with PSA at 220. Since then he has been on Zoladex, Enzalutamide and has just finished 8 rounds of Docetaxel. Apart from this cancer he is very healthy - but what happens now when the PSA starts rising again. He
Bongoed
in
Advanced Prostate Cancer
3 months ago
Prolia and prednisone together = higher infection risk
https://www.drugs.com/drug-interactions/prednisone-with-prolia-1936-0-3238-14600.html From the "we never stop learning angles about APCa and related treatments" zone Wear a mask etc
https://www.drugs.com/drug-interactions/prednisone-with-prolia-1936-0-3238-14600.html From the "we never stop learning angles about APCa and related treatments" zone Wear a mask etc
Derf4223
in
Advanced Prostate Cancer
3 months ago
Please advise about treatment
I posted recently about my Dad’s PSA going up from 0.008 in December 2023 to 0.029 in March 2024. He had a PET Scan that showed some activity in a rib and prostate, MRI showed nothing. The PSA started dropping to 0.026 at the end of March and then 0.025 in April without any treatment. We didn’t anticipate
I posted recently about my Dad’s PSA going up from 0.008 in December 2023 to 0.029 in March 2024. He had a PET Scan that showed some activity in a rib and prostate, MRI showed nothing. The PSA started dropping to 0.026 at the end of March and then 0.025 in April without any treatment. We didn’t anticipate
Simonapo
in
Advanced Prostate Cancer
3 months ago
Three Big Challenges in Metastatic PC
Common themes that often emerge from the posts and responses on this particular hub of HU are intermittent and alternative therapy, the use of testosterone replacement and the various associated issues. In the latest GU podcast, co-hosts Dr Declan Murphy and Renu Eapen from [i]Peter MacCallum Cancer
Common themes that often emerge from the posts and responses on this particular hub of HU are intermittent and alternative therapy, the use of testosterone replacement and the various associated issues. In the latest GU podcast, co-hosts Dr Declan Murphy and Renu Eapen from [i]Peter MacCallum Cancer
marnieg46
in
Fight Prostate Cancer
3 months ago
Caffeine shown to affect brain dopamine function in patients with Parkinson's disease
Regular high caffeine consumption affects dopamine function in patients with Parkinson's disease, shows a new international study led by the University of Turku and Turku University Hospital in Finland. Caffeine consumption before undergoing diagnostic brain dopamine imaging may also affect the imaging
Regular high caffeine consumption affects dopamine function in patients with Parkinson's disease, shows a new international study led by the University of Turku and Turku University Hospital in Finland. Caffeine consumption before undergoing diagnostic brain dopamine imaging may also affect the imaging
JCRO
in
Cure Parkinson's
3 months ago
PSA test after TRUS Biopsy ?
Would a trus biopsy affect psa results. How many days after a biopsy can one get a psa done doc has said to get biopsy done and then meet him with biopsy results and a fresh psa even though psa was done 3 weeks back and was 18
Would a trus biopsy affect psa results. How many days after a biopsy can one get a psa done doc has said to get biopsy done and then meet him with biopsy results and a fresh psa even though psa was done 3 weeks back and was 18
Tinkudi
in
Advanced Prostate Cancer
3 months ago
EPIX: Updated Data From Phase 1 Trial Of Masofaniten And Enzalutamide Expected
Source link : https://scr.zacks.com/news/news-details/2024/EPIX-Updated-Data-from-Phase-1-Trial-of-Masofaniten-and-Enzalutamide-Expected-in-2H24-article/default.aspx The median PSA baseline for this study was 3.2 ng/mL, which on the surface may look like it is quite different from the other studies
Source link : https://scr.zacks.com/news/news-details/2024/EPIX-Updated-Data-from-Phase-1-Trial-of-Masofaniten-and-Enzalutamide-Expected-in-2H24-article/default.aspx The median PSA baseline for this study was 3.2 ng/mL, which on the surface may look like it is quite different from the other studies
God_Loves_Me
in
Advanced Prostate Cancer
3 months ago
Lupron + abi/pred 9 months and PSA<.04 throughout - - consider dropping abi and monitor it?
I am a recurrence case and PSA went to 2.2 last year; multiple possible sites. After 9 months in now, PSA <.04 and TT <10 the whole time. Hopkins MO says he would not risk stopping the abi despite the immeasurable PSA whereas Moffitt MO says he would stop the abi since it "seems" not so needed and
I am a recurrence case and PSA went to 2.2 last year; multiple possible sites. After 9 months in now, PSA <.04 and TT <10 the whole time. Hopkins MO says he would not risk stopping the abi despite the immeasurable PSA whereas Moffitt MO says he would stop the abi since it "seems" not so needed and
jackwfrench
in
Advanced Prostate Cancer
3 months ago
Who is confused? My surgery or me?
I was asked by the GP to remind him, when I reached 3mg in my tapering, that I should have a synacthen test. I have now done so. However, I am being sent for an ACTH blood test Is this the same thing (I don't think so as I have not been asked to miss the steroid dose and there is no indication that
I was asked by the GP to remind him, when I reached 3mg in my tapering, that I should have a synacthen test. I have now done so. However, I am being sent for an ACTH blood test Is this the same thing (I don't think so as I have not been asked to miss the steroid dose and there is no indication that
ChinaWuntoo
in
PMRGCAuk
3 months ago
is this what CR looks like?
Starting Nov 20 last year, I began a relugolix on-cycle. Here’s the PSA readings from that point: Nov 20 : 3.10 Jan 8: 0.31 Feb 27: 0.13 Apr 15: 0.08 So up to this point, the PSA is dropping nicely, as it always has with on-cycles; and as I would expect, since I’ve been a strong responder
Starting Nov 20 last year, I began a relugolix on-cycle. Here’s the PSA readings from that point: Nov 20 : 3.10 Jan 8: 0.31 Feb 27: 0.13 Apr 15: 0.08 So up to this point, the PSA is dropping nicely, as it always has with on-cycles; and as I would expect, since I’ve been a strong responder
lokibear0803
in
Advanced Prostate Cancer
3 months ago
Diuretics
I have pretty severe edema in feet and occasionally legs.Is there a diuretic that does not trigger rls? I have tried Bumex and Metolazone. Had very bad rls soon after taking each one. I am on low dose Ropinirole -.9mg . It didn't even calm it. Appreciate any input.
I have pretty severe edema in feet and occasionally legs.Is there a diuretic that does not trigger rls? I have tried Bumex and Metolazone. Had very bad rls soon after taking each one. I am on low dose Ropinirole -.9mg . It didn't even calm it. Appreciate any input.
rmbroadh
in
Restless Legs Syndrome
3 months ago
Questions regarding dialysis and also transplant
Hi Everyone, Hope everyone is ok with all the crazy weather that has taken place all over. I recently started hemodialysis in the last week. Once again I have had to learn everything from you all or reading online/or in books which is not overly helpful at times. The dialysis center folks think my nephrologist
Hi Everyone, Hope everyone is ok with all the crazy weather that has taken place all over. I recently started hemodialysis in the last week. Once again I have had to learn everything from you all or reading online/or in books which is not overly helpful at times. The dialysis center folks think my nephrologist
Missingthesun
in
Kidney Dialysis
3 months ago
Erleada or Xtandi with Orgovyx, preference one way or the other?
Dx 2015 Gleason 7, prostatectomy 2015, seminal vessel invasion one side, fast forward 3 years recurrence and 39 sessions of radiation to prostate bed and back to PSA undetectable. Fast forward to fall of 2019 PSA back to 4.3 PSMA Pet scan shows iliac crest area met along with lymph nodes prostate bed
Dx 2015 Gleason 7, prostatectomy 2015, seminal vessel invasion one side, fast forward 3 years recurrence and 39 sessions of radiation to prostate bed and back to PSA undetectable. Fast forward to fall of 2019 PSA back to 4.3 PSMA Pet scan shows iliac crest area met along with lymph nodes prostate bed
Wynnsts
in
Advanced Prostate Cancer
3 months ago
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