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Improved Outcomes Using Biomarker-Guided Therapy Selection for Metastatic Prostate Cancer
ProBio trial uses biomarkers to help designing an individual treatment strategy https://www.urotoday.com/video-lectures/mcrpc-treatment/video/mediaitem/3789-probio-trial-demonstrates-improved-outcomes-using-biomarker-guided-therapy-selection-for-metastatic-prostate-cancer-henrik-groenberg.html
ProBio trial uses biomarkers to help designing an individual treatment strategy https://www.urotoday.com/video-lectures/mcrpc-treatment/video/mediaitem/3789-probio-trial-demonstrates-improved-outcomes-using-biomarker-guided-therapy-selection-for-metastatic-prostate-cancer-henrik-groenberg.html
Maxone73
in
Advanced Prostate Cancer
6 months ago
Skull met!
I am receiving radiation on a skull med on my left side, just passed my optical nerve area. I am wondering if I should have another MRI after the fifth or sixth radiation treatment to see if the med has been eliminated or should they continue on with the complete 10 treatments? any suggestions would
I am receiving radiation on a skull med on my left side, just passed my optical nerve area. I am wondering if I should have another MRI after the fifth or sixth radiation treatment to see if the med has been eliminated or should they continue on with the complete 10 treatments? any suggestions would
docbulldog
in
Advanced Prostate Cancer
2 months ago
Well, three years in…..
Since initial DX of Gleason 4+4….. at that time was stage 4 high volume metastic disease. PSA can move up and down quickly. went up 10 points in a week went down 33 points in a month, without treatment. i went from NED of disease to PSA of 28.5 in six months. it’s a spunky little bastard. sorta like
Since initial DX of Gleason 4+4….. at that time was stage 4 high volume metastic disease. PSA can move up and down quickly. went up 10 points in a week went down 33 points in a month, without treatment. i went from NED of disease to PSA of 28.5 in six months. it’s a spunky little bastard. sorta like
FulThrotl
in
Advanced Prostate Cancer
2 months ago
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Companies that test liver biospy tissue to see what immunotherapy, parp inhibitors or ATK inhibitors would work?
as above, so far pca Adenocarcinoma in liver biopsy tissue…. Anyone have a list?
as above, so far pca Adenocarcinoma in liver biopsy tissue…. Anyone have a list?
Shorehousejam
in
Advanced Prostate Cancer
2 months ago
Worsening back pain after treatment?
I’ve had back pain before, and even had surgery to relieve it, but this is different. I’ve brought this up with my RO and my plain oncologist, but wanted to see if anyone here has experienced this. Next week I’ll be talking to my GP. A reminder of my DX: Gleason 9, spread to local lymph nodes. Treated
I’ve had back pain before, and even had surgery to relieve it, but this is different. I’ve brought this up with my RO and my plain oncologist, but wanted to see if anyone here has experienced this. Next week I’ll be talking to my GP. A reminder of my DX: Gleason 9, spread to local lymph nodes. Treated
Jpburns
in
Advanced Prostate Cancer
2 months ago
Scared of the Future.....
My husband (42M) has been having the feeling of needing to use the bathroom 7-10 times a day, and it always comes out as gas or diarrhea, loose watery stools. I had him to our primary doctor and get some tests run. All of his bloodwork has come back ok, his platelets are a little high, but his iFOBT
My husband (42M) has been having the feeling of needing to use the bathroom 7-10 times a day, and it always comes out as gas or diarrhea, loose watery stools. I had him to our primary doctor and get some tests run. All of his bloodwork has come back ok, his platelets are a little high, but his iFOBT
MisSchulte
in
Colon Cancer Connected
2 months ago
Disappointed
After Lupron, NUBEQA and Zytega … and a recent FDG Cat scan Several nodes lit up in the periodonal aorta area of his abdomen. Being totally right up against the aorta, a decision was made to remove them robotically. Surgery went well. All lymph’s were removed that lit up on the scan. docs felt PSA
After Lupron, NUBEQA and Zytega … and a recent FDG Cat scan Several nodes lit up in the periodonal aorta area of his abdomen. Being totally right up against the aorta, a decision was made to remove them robotically. Surgery went well. All lymph’s were removed that lit up on the scan. docs felt PSA
JolleySprings
in
Advanced Prostate Cancer
2 months ago
Update Castrate Resistant Metastatic Cancer
My metastatic prostate cancer was diagnosed castrate resistant on November 1 with PSA of 0.8, which was doubling in about two months while on Lupron. On November 10 I started Abiraterone + prednisone. By December 1 my PSA dropped to 0.44 in 22 days on Abiraterone. In the next 35 days it went down to
My metastatic prostate cancer was diagnosed castrate resistant on November 1 with PSA of 0.8, which was doubling in about two months while on Lupron. On November 10 I started Abiraterone + prednisone. By December 1 my PSA dropped to 0.44 in 22 days on Abiraterone. In the next 35 days it went down to
dac500
in
Advanced Prostate Cancer
7 months ago
Thank you Angela for sharing your story!
“I have never really been a sun worshipper but I have used sunbeds in the past. I used to hire one for use at home in my late teens/early 20’s then used the stand-up ones on and off at tanning salons a few years after that. I never thought there was any harm in using sunbeds and I can’t remember seeing
“I have never really been a sun worshipper but I have used sunbeds in the past. I used to hire one for use at home in my late teens/early 20’s then used the stand-up ones on and off at tanning salons a few years after that. I never thought there was any harm in using sunbeds and I can’t remember seeing
SkcinHQ
Partner
in
Skin Cancer UK
2 months ago
Disgusted with Healthcare
I had to request my PCP to do a PSA as it wasn't standard practice. I had to call the urologist, who I originally saw, after I joined this board and knew I should be starting ADT, even though they hadn't two months after my scans showed Stage IV. I saw the surgeon even though it was Stage IV and wasn't
I had to request my PCP to do a PSA as it wasn't standard practice. I had to call the urologist, who I originally saw, after I joined this board and knew I should be starting ADT, even though they hadn't two months after my scans showed Stage IV. I saw the surgeon even though it was Stage IV and wasn't
Vangogh1961
in
Advanced Prostate Cancer
2 months ago
Androlic acid
8 yrs ago I was diagnosed with breast cancer , I had lumpectomy , chemo , radio therapy . ongoing hormonal blockers for another 4 yrs, my oncologist wants me to start androlic acid to help my bones after a dexa scan showed I had oastiopenia . I really do not want to start the meds and am very anxious
8 yrs ago I was diagnosed with breast cancer , I had lumpectomy , chemo , radio therapy . ongoing hormonal blockers for another 4 yrs, my oncologist wants me to start androlic acid to help my bones after a dexa scan showed I had oastiopenia . I really do not want to start the meds and am very anxious
SjDexDolly
in
PMRGCAuk
2 months ago
New Developments in My Husband's PCA Journey
Hello, I wanted to provide an update on my husband's progression and, hopefully, some of you may have some knowledge to share or have a similar profile. His psa has risen from <0.04 since RP for Stage 3b to 0.06 in 9/23. A recheck a week later showed a rise to 0.1. This was followed by a drop to <.04
Hello, I wanted to provide an update on my husband's progression and, hopefully, some of you may have some knowledge to share or have a similar profile. His psa has risen from <0.04 since RP for Stage 3b to 0.06 in 9/23. A recheck a week later showed a rise to 0.1. This was followed by a drop to <.04
103532
in
Advanced Prostate Cancer
7 months ago
Appointment update
Well guys, I've had my appointment today at the head and neck cancer clinic.I do not have head & neck cancer on my lungs I have lung cancer of various types in miniscule sizes that are causing me no problems at the moment. I will have 3 monthly ct scan 2 see if they grow if not have anything done, if
Well guys, I've had my appointment today at the head and neck cancer clinic.I do not have head & neck cancer on my lungs I have lung cancer of various types in miniscule sizes that are causing me no problems at the moment. I will have 3 monthly ct scan 2 see if they grow if not have anything done, if
Mindini1964
in
The Roy Castle Lung Cancer Foundation
7 months ago
Any updates on the 2019 Italian work on CRISPR-CAS9 that anyone knows about?
I am referring to this article: Targeting Interleukin(IL)-30/IL-27p28 signaling in cancer stem-like cells and host environment synergistically inhibits prostate cancer growth and improves survival https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670138/ https://www.labiotech.eu/trends-news/crispr-deletion-interleukin
I am referring to this article: Targeting Interleukin(IL)-30/IL-27p28 signaling in cancer stem-like cells and host environment synergistically inhibits prostate cancer growth and improves survival https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670138/ https://www.labiotech.eu/trends-news/crispr-deletion-interleukin
PCreader
in
Advanced Prostate Cancer
7 months ago
Please suggest "must read" articles for men diagnosed with an advanced stage of prostate cancer
If your prostate cancer knowledge seeking includes reading peer-reviewed articles, please suggest "must read" articles for men diagnosed with an advanced stage of prostate cancer and perhaps for their family members, too.
If your prostate cancer knowledge seeking includes reading peer-reviewed articles, please suggest "must read" articles for men diagnosed with an advanced stage of prostate cancer and perhaps for their family members, too.
Darryl
Partner
in
Advanced Prostate Cancer
7 months ago
PSA suppression
My PSA lows tend to be around 3.3, and it occurs to me that some might think it odd that I don't drive it lower. I think it is very common for men on ADT to draw too much comfort from a significant PSA reduction, if not a near-zero PSA. I have witnessed men misinterpret a dramatic drop in PSA as
My PSA lows tend to be around 3.3, and it occurs to me that some might think it odd that I don't drive it lower. I think it is very common for men on ADT to draw too much comfort from a significant PSA reduction, if not a near-zero PSA. I have witnessed men misinterpret a dramatic drop in PSA as
pca2004
in
Fight Prostate Cancer
7 months ago
The FDA on Thursday approved Amgen’s bispecific T-cell engager tarlatamab, [i][b] also developing for neuroendocrine prostate cancer[/b][/i]
The FDA on Thursday approved Amgen’s bispecific T-cell engager tarlatamab, which will now carry the brand name Imdelltra, for the treatment of extensive-stage small lung cancer in patients with disease progression on or after platinum chemotherapy. Imdelltra is approved under the regulator’s accelerated
The FDA on Thursday approved Amgen’s bispecific T-cell engager tarlatamab, which will now carry the brand name Imdelltra, for the treatment of extensive-stage small lung cancer in patients with disease progression on or after platinum chemotherapy. Imdelltra is approved under the regulator’s accelerated
Scout4answers
in
Advanced Prostate Cancer
2 months ago
Questions
I saw my PSA suddenly rise to 3.67 in January 2023. My PMD was not overly concerned as it was under 4. His plan was to repeat it in 6 months. I will also not I was on Tamsulosin and Finasteride for some time at that point for urinary frequency. That started several years before (at that time I was
I saw my PSA suddenly rise to 3.67 in January 2023. My PMD was not overly concerned as it was under 4. His plan was to repeat it in 6 months. I will also not I was on Tamsulosin and Finasteride for some time at that point for urinary frequency. That started several years before (at that time I was
Cleantop
in
Advanced Prostate Cancer
7 months ago
Running post cancer
So a shock diagnosis of colon cancer last year, surgery and chemo and I'm now doing c25k for a second time hoping that exercise can have some beneficial effect in keeping me healthy. Anyone else in this situation?
So a shock diagnosis of colon cancer last year, surgery and chemo and I'm now doing c25k for a second time hoping that exercise can have some beneficial effect in keeping me healthy. Anyone else in this situation?
RamblingMe
Graduate
in
Couch to 5K
2 months ago
Update on Failing Pirtobrutinib
After 8 months on pirto, my specialist confirmed the drug is indeed no longer working. We discussed 2 options, CAR-T (not a trial) and a BTK degrader trial at Penn. After a long explanation of how they handle the CAR-T procedure, (it is done on an outpatient basis). Along with all the major risks and
After 8 months on pirto, my specialist confirmed the drug is indeed no longer working. We discussed 2 options, CAR-T (not a trial) and a BTK degrader trial at Penn. After a long explanation of how they handle the CAR-T procedure, (it is done on an outpatient basis). Along with all the major risks and
ReneeSusan
in
CLL Support
2 months ago
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