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Promising, especially for people with LBD mutation: NEJM Evidence publishes results from Phase I/IIa CYPIDES trial with ODM-208
Median circulating
testosterone
levels declined from 3.0 ng/dl at baseline to undetectable levels within the first week of ODM-208 treatment in 46/53 (87%) patients." https://www.biospace.com/article/releases/nejm-evidence-publishes-results-from-phase-i-iia-cypides-trial-with-odm-208/
Median circulating
testosterone
levels declined from 3.0 ng/dl at baseline to undetectable levels within the first week of ODM-208 treatment in 46/53 (87%) patients." https://www.biospace.com/article/releases/nejm-evidence-publishes-results-from-phase-i-iia-cypides-trial-with-odm-208/
Maxone73
in
Advanced Prostate Cancer
4 months ago
Androstenedione & Frailty
When I eventually migrated to 3 mg DES - plus a shot of
testosterone
cypionate every 3 months - I began to feel frail. The new study associates high levels of androstenedione [andro] with frailty.
When I eventually migrated to 3 mg DES - plus a shot of
testosterone
cypionate every 3 months - I began to feel frail. The new study associates high levels of androstenedione [andro] with frailty.
pca2004
in
Fight Prostate Cancer
5 months ago
Blood test results
Method: Roche Cobas Thyroid Peroxidase Antibodies <9 0 - 34 kIU/L Method: Roche Coba ENDOCRINOLOGY Luteinising Hormone 18.7 IU/L 17-Beta Oestradiol 2445.0 pmol/L Sex Hormone Binding Glob H 157 27.1 - 128 nmol/L Prolactin 201 102 - 496 mIU/L Please note change of reference range 23 Oct 2022
Testosterone
Method: Roche Cobas Thyroid Peroxidase Antibodies <9 0 - 34 kIU/L Method: Roche Coba ENDOCRINOLOGY Luteinising Hormone 18.7 IU/L 17-Beta Oestradiol 2445.0 pmol/L Sex Hormone Binding Glob H 157 27.1 - 128 nmol/L Prolactin 201 102 - 496 mIU/L Please note change of reference range 23 Oct 2022
Testosterone
Blu-cat11
in
Thyroid UK
18 days ago
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1st PSA Post SBRT + ADT: A Bounce?
At the end of ADT, my PSA was <0.05 and
Testosterone
was 4. My first PSA Test was last Wednesday at Penn Medicine in Philly (9 months post RT and 4.5 months post ADT):
Testosterone
back: 431. PSA jumped to 2.069.
At the end of ADT, my PSA was <0.05 and
Testosterone
was 4. My first PSA Test was last Wednesday at Penn Medicine in Philly (9 months post RT and 4.5 months post ADT):
Testosterone
back: 431. PSA jumped to 2.069.
Longrunner
in
Prostate Cancer Network
7 months ago
help with bloods.
The results were: Serum oestradiol level 368 pmol/L
Testosterone
(MS) 3.6 nmol/L Androstenedione 1.00 nmol/L FREE ANDROGEN INDEX (MS) 7.2% 0.2 - 3.6 SHBG - AUTOMATION 50 nmol/L 27 - 128 17 - HYDROXY PROGESTERONE <0.3 nmol/L 0.4 - 5.0 I'm hoping these bloods
The results were: Serum oestradiol level 368 pmol/L
Testosterone
(MS) 3.6 nmol/L Androstenedione 1.00 nmol/L FREE ANDROGEN INDEX (MS) 7.2% 0.2 - 3.6 SHBG - AUTOMATION 50 nmol/L 27 - 128 17 - HYDROXY PROGESTERONE <0.3 nmol/L 0.4 - 5.0 I'm hoping these bloods
WendyW1964
in
Menopause and Perimenopause Support
2 months ago
3 Abiraterone tabs in place of 4.
Recently had blood work done that showed my PSA has moved from 0.04 to <0,04 and the
Testosterone
had not moved from the <7.00 ng/dl. So with this small sample of results there were really no change in ADT effectiveness.
Recently had blood work done that showed my PSA has moved from 0.04 to <0,04 and the
Testosterone
had not moved from the <7.00 ng/dl. So with this small sample of results there were really no change in ADT effectiveness.
85236442968
in
Advanced Prostate Cancer
9 days ago
Morgentaler Saturation Model: PSA vs Testosterone - Estrogen Patch vs Lupron ADT
This is a plot of % reduction in PSA from a Maximum Value versus
Testosterone
, for two different datasets: Estrogen Patch and Lupron ADT. Both curves (red and green lines) show a linear response starting from (0,0), up to about 200-250 ng/dL.
This is a plot of % reduction in PSA from a Maximum Value versus
Testosterone
, for two different datasets: Estrogen Patch and Lupron ADT. Both curves (red and green lines) show a linear response starting from (0,0), up to about 200-250 ng/dL.
janebob99
in
Advanced Prostate Cancer
2 months ago
I've been failed
All she talked about was how "girls with PCOS are smarter because they have so much
testosterone
." I didn't go there to hear a bunch of misogynistic rubbish.
All she talked about was how "girls with PCOS are smarter because they have so much
testosterone
." I didn't go there to hear a bunch of misogynistic rubbish.
IveBeenFailed
in
PCOS UK (Verity)
4 months ago
Provenge criteria necessary for acceptance.
But are there other requirements like certain PSA parameters and lower
testosterone
levels? Do we have to remain on ADT while being treated with Provenge?
But are there other requirements like certain PSA parameters and lower
testosterone
levels? Do we have to remain on ADT while being treated with Provenge?
SViking
in
Advanced Prostate Cancer
7 months ago
BAT trial
I am now in the trial and have had my first
testosterone
injections plus the carboplatin infusion.
I am now in the trial and have had my first
testosterone
injections plus the carboplatin infusion.
Bjry
in
Advanced Prostate Cancer
7 months ago
declining psa #7
Solely using ivermectin, cbd oil, turmeric, zinc and now
testosterone
boosters ashwagandha, cordyceps extract and diindolylmethane(dim) which is an estrogen blocker. Psa has dropped to 1.29 down from 1.34 last month and 1.92 nine months ago,
testosterone
at 467.
Solely using ivermectin, cbd oil, turmeric, zinc and now
testosterone
boosters ashwagandha, cordyceps extract and diindolylmethane(dim) which is an estrogen blocker. Psa has dropped to 1.29 down from 1.34 last month and 1.92 nine months ago,
testosterone
at 467.
Nfler
in
Advanced Prostate Cancer
6 months ago
MOST RECENT PSA and TESTOSTERONE TEST
My PSA and
testosterone
test results have been PSA .01 and T 11 since July of 2022. I had my quarterly test done yesterday and my PSA is at .02 and T is at 21.5. They are still undetectable, but not sure what caused the rise.
My PSA and
testosterone
test results have been PSA .01 and T 11 since July of 2022. I had my quarterly test done yesterday and my PSA is at .02 and T is at 21.5. They are still undetectable, but not sure what caused the rise.
GMan-62
in
Advanced Prostate Cancer
6 months ago
Help with blood results
I wonder if it is linked to the introduction of
testosterone
, I started hrt end of January this year (gel and utrogestan) and
testosterone
2 weeks ago. I had an advanced thyroid panel at medichecks last week and my antibodies are clear. Vitamin D low to normal and ferritin is low.
I wonder if it is linked to the introduction of
testosterone
, I started hrt end of January this year (gel and utrogestan) and
testosterone
2 weeks ago. I had an advanced thyroid panel at medichecks last week and my antibodies are clear. Vitamin D low to normal and ferritin is low.
Rambler16
in
Thyroid UK
5 months ago
IS THIS A PATTERN???? Thoughts and helpful ideas to guide a path
They have said they would not be concerned until PSA reached 2 I do not know what my
testosterone
levels are???? any thoughts, questions and guidance would be appreciated
They have said they would not be concerned until PSA reached 2 I do not know what my
testosterone
levels are???? any thoughts, questions and guidance would be appreciated
Mrtroxely
in
Advanced Prostate Cancer
3 months ago
Bicalutamide
The thing I don’t understand is during the visit to the Urologist to discuss his biopsy results, the urologist prescribed 50mg of Bicalutamide to begin reducing his
testosterone
. I believe this is premature. What does this esteemed group say?
The thing I don’t understand is during the visit to the Urologist to discuss his biopsy results, the urologist prescribed 50mg of Bicalutamide to begin reducing his
testosterone
. I believe this is premature. What does this esteemed group say?
OFPF16
in
Advanced Prostate Cancer
5 months ago
RT with ADT Relogolix (Orgovyx) vs Enzalutamide (Xtandi) Side Effect Differences?
Of note, Enzalutamide has direct radio sensitizing properties where ADT drugs only have an indirect radio sensitizing effect from lowering
Testosterone
.
Of note, Enzalutamide has direct radio sensitizing properties where ADT drugs only have an indirect radio sensitizing effect from lowering
Testosterone
.
jazj
in
Advanced Prostate Cancer
2 months ago
help please - severe osteoporosis-3.5 on DEXA scan I’m just 48
I haven’t started hrt so no wonder my Bones are terrible I haven’t had a period for 10 years I can’t even remember Can anyone please advise Freaking out Xx I have been prescribed oestrogen gel and progesterone pills What about
testosterone
?
I haven’t started hrt so no wonder my Bones are terrible I haven’t had a period for 10 years I can’t even remember Can anyone please advise Freaking out Xx I have been prescribed oestrogen gel and progesterone pills What about
testosterone
?
Chouchou1234
in
Thyroid UK
5 months ago
Doubling Times and PSA acceleration - Part II
You can use the DT calculator at: https://www.mskcc.org/nomograms/prostate/psa_doubling_time Decreasing the
testosterone
levels to sub-castrate levels (T < 10 ng/dL) are the best way to stop this rapid rise in PSA over time.
You can use the DT calculator at: https://www.mskcc.org/nomograms/prostate/psa_doubling_time Decreasing the
testosterone
levels to sub-castrate levels (T < 10 ng/dL) are the best way to stop this rapid rise in PSA over time.
janebob99
in
Prostate Cancer Network
2 months ago
Latest Thyroid Results
My
testosterone
is over-range and may be contributing to the better energy levels I have and more stable SHBG as it was undetectable last time I had it tested, I will now reduce my dose to fit ranges.
My
testosterone
is over-range and may be contributing to the better energy levels I have and more stable SHBG as it was undetectable last time I had it tested, I will now reduce my dose to fit ranges.
Jamima
in
Thyroid UK
3 months ago
Endocrinology and Hormones
But after seeing the Endocrinologist and getting on
testosterone
replacement therapy and adding the needed supplements to my diet It changed my life.
But after seeing the Endocrinologist and getting on
testosterone
replacement therapy and adding the needed supplements to my diet It changed my life.
62BlackBirds
in
Anxiety and Depression Support
3 months ago
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