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Tamoxifen
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A very cool link for all inhibitors that you can download
Endoxifen HCl, the active metabolite of
Tamoxifen
, ia a potent and selective estrogen receptor antagonist. Phase 2. Enzalutamide (MDV3100) is an androgen-receptor (AR) antagonist with IC50 of 36 nM in LNCaP cells. Enzalutamide is shown to increase autophagy.
Endoxifen HCl, the active metabolite of
Tamoxifen
, ia a potent and selective estrogen receptor antagonist. Phase 2. Enzalutamide (MDV3100) is an androgen-receptor (AR) antagonist with IC50 of 36 nM in LNCaP cells. Enzalutamide is shown to increase autophagy.
KocoPr
in
Advanced Prostate Cancer
2 years ago
Mixed response to treatment , not the results I was expecting from Paclitaxel,perjeta & herceptin.
She is also suggesting going back on the Paclitaxel or trying Kadcyla ( keeping hair ) she also mentioned re introducing
tamoxifen
as I have not had it in 15 years . Has anyone reintroduced a medication after a long absence ? Did it work ? And any tips on Kadcyla ? Thank you , LuannšØš¦
She is also suggesting going back on the Paclitaxel or trying Kadcyla ( keeping hair ) she also mentioned re introducing
tamoxifen
as I have not had it in 15 years . Has anyone reintroduced a medication after a long absence ? Did it work ? And any tips on Kadcyla ? Thank you , LuannšØš¦
Hidden
in
SHARE Metastatic Breast Cancer
2 years ago
CT exam revealed endometrium thickness and biopsy confirmed the endometrium cancer. I have MBC
I was on
tamoxifen
for two years when I had my primary breast cancer 10 years ago and from July to September now Thank you so much Marina
I was on
tamoxifen
for two years when I had my primary breast cancer 10 years ago and from July to September now Thank you so much Marina
Cureforever
in
SHARE Metastatic Breast Cancer
2 years ago
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Has anyone tried using Herb Pharm, Thyroid Calming?
I also take
Tamoxifen
(I had breast cancer in 2016/17) which I'm due to finish up with in July! I'm longing for a day when I no longer need any meds!
I also take
Tamoxifen
(I had breast cancer in 2016/17) which I'm due to finish up with in July! I'm longing for a day when I no longer need any meds!
MyNameIsAugust
in
Thyroid UK
2 years ago
So glad I found this site
Diagnosed with BC when I was 46, bi lat mastectomy, chemo and
tamoxifen
. Mets to spine this year after 25 years cancer free. On letrozole and finished radiation. Trying to decide if I really want to take verzenio now or wait a while. The side effects look awful..
Diagnosed with BC when I was 46, bi lat mastectomy, chemo and
tamoxifen
. Mets to spine this year after 25 years cancer free. On letrozole and finished radiation. Trying to decide if I really want to take verzenio now or wait a while. The side effects look awful..
Peggypilot
in
SHARE Metastatic Breast Cancer
2 years ago
Pet Ct Findings
I was also on
Tamoxifen
before Xeloda for three months. Xeloda is my fifth line of treatment over 2.5 years. Does anyone have this? I am so upset and very nervous. Thank you Marina.
I was also on
Tamoxifen
before Xeloda for three months. Xeloda is my fifth line of treatment over 2.5 years. Does anyone have this? I am so upset and very nervous. Thank you Marina.
Cureforever
in
SHARE Metastatic Breast Cancer
2 years ago
Breast Cancer Research for Chemotherapy Induced Cognitive Changes!!!
I am now taking
tamoxifen
for hormonal control. As many of you may have experienced, I noticed a great deal of brain fog and cognitive changes while on chemotherapy treatment and thereafter.
I am now taking
tamoxifen
for hormonal control. As many of you may have experienced, I noticed a great deal of brain fog and cognitive changes while on chemotherapy treatment and thereafter.
Brodum
in
SHARE Breast Cancer Support
2 years ago
Safe Weight Bearing
I was diagnosed with osteoporosis after 5 yrs on estrogen inhibitor,
Tamoxifen
, and immediately put on Prolia in 2014. A recent bone scan indicates treatment is no longer effective, my results indicate osteoporosis of the spine and hips.
I was diagnosed with osteoporosis after 5 yrs on estrogen inhibitor,
Tamoxifen
, and immediately put on Prolia in 2014. A recent bone scan indicates treatment is no longer effective, my results indicate osteoporosis of the spine and hips.
Seacrab
in
Osteoporosis Support
2 years ago
Stunned, scared, sad, but grateful and happy to be here!
Chemo and radiation. 7.5 years
Tamoxifen
then switched to Letrozole for 1.5 years. Almost done! Or so I thought. Then right after my ten years, in Septemberā21 diagnosed with MBC (now just Er+) to liver and bones with some node involvement. Started Ibrance/Fulvestrant/Xgeva.
Chemo and radiation. 7.5 years
Tamoxifen
then switched to Letrozole for 1.5 years. Almost done! Or so I thought. Then right after my ten years, in Septemberā21 diagnosed with MBC (now just Er+) to liver and bones with some node involvement. Started Ibrance/Fulvestrant/Xgeva.
Fifilatour
in
SHARE Metastatic Breast Cancer
2 years ago
Tamoxifen and allele
tamoxifen
treatment, 3 responders showed at least a 50% reduction in VAF, which was the studyās primary end point.
tamoxifen
treatment, 3 responders showed at least a 50% reduction in VAF, which was the studyās primary end point.
EPguy
in
MPN Voice
3 years ago
Estradiol just won't go down
Best anyone can come up with is to try
tamoxifen
which blocks the estradiol receptors. I have been taking DIM, Chrysin and Grape Seed extract, but none of those seem to put a dent in this issue. Any other experiences with this and how to deal with it?
Best anyone can come up with is to try
tamoxifen
which blocks the estradiol receptors. I have been taking DIM, Chrysin and Grape Seed extract, but none of those seem to put a dent in this issue. Any other experiences with this and how to deal with it?
Arthur479
in
Advanced Prostate Cancer
3 years ago
Are there any members of this group that currently have metastatic breast cancer that has spread to the abdomen/stomach area?"
My original diagnosis (1995) was invasive lobular carcinoma (mastectomy, chemotherapy, and
tamoxifen
), and I had a local recurrence to the chest wall in 2005 (radiation and Femara).
My original diagnosis (1995) was invasive lobular carcinoma (mastectomy, chemotherapy, and
tamoxifen
), and I had a local recurrence to the chest wall in 2005 (radiation and Femara).
PeabodyTerrace
in
SHARE Metastatic Breast Cancer
2 years ago
Tamoxifen vs letrazole
Hi My consultant is thinking of changing my medication from
tamoxifen
which I have been on for 5 years . So I have stopped taking it and Im due bloods in January to see if Iām post menaposal and if this is the case I could take letrazole which she informed me was superior to
tamoxifen
.
Hi My consultant is thinking of changing my medication from
tamoxifen
which I have been on for 5 years . So I have stopped taking it and Im due bloods in January to see if Iām post menaposal and if this is the case I could take letrazole which she informed me was superior to
tamoxifen
.
Julie-1969
in
My Breast Cancer Community
3 years ago
Same as Carole, ānew....well sort of ; )ā
Having a mastectomy, lymph node excision, 8 cycles of chemo (red devil, Docetaxel ) 16 cycles of Herceptin followed by 6 weeks of daily radiation and
tamoxifen
. During regular check on 2017, became MBC, ER+HER2-. Metastasized to the other side of lymph nodes and plural.
Having a mastectomy, lymph node excision, 8 cycles of chemo (red devil, Docetaxel ) 16 cycles of Herceptin followed by 6 weeks of daily radiation and
tamoxifen
. During regular check on 2017, became MBC, ER+HER2-. Metastasized to the other side of lymph nodes and plural.
s_yenju
in
SHARE Metastatic Breast Cancer
3 years ago
Tumour markers
Heās carried on with
Tamoxifen
and blood strengtheners, and Iāll see him (face to face) in the New Year after my usual CT scan. Thanks for listening, and have a great day š
Heās carried on with
Tamoxifen
and blood strengtheners, and Iāll see him (face to face) in the New Year after my usual CT scan. Thanks for listening, and have a great day š
Otis123
in
SHARE Metastatic Breast Cancer
3 years ago
Momās MBC Diagnosis - Intro & Questions
She had surgery, chemo, radiation and 5 years of
tamoxifen
. December 2021, sheās received a metastatic diagnosis. She had a routine mammogram in August which was clear. In October, she rubbed her neck and felt swelling along with a small noticeable lymph node.
She had surgery, chemo, radiation and 5 years of
tamoxifen
. December 2021, sheās received a metastatic diagnosis. She had a routine mammogram in August which was clear. In October, she rubbed her neck and felt swelling along with a small noticeable lymph node.
ntalley8
in
SHARE Metastatic Breast Cancer
3 years ago
Headache and exemestane? What to do?
She has just switched from
Tamoxifen
to exemestane . From the second day she started taking exemestane , she got a terrible headache. That continues now for about a week. Has anyone experienced similar headache while on exemestane? Could it be considered a side effect? Or maybe something else??
She has just switched from
Tamoxifen
to exemestane . From the second day she started taking exemestane , she got a terrible headache. That continues now for about a week. Has anyone experienced similar headache while on exemestane? Could it be considered a side effect? Or maybe something else??
ERPRposHER2-
in
SHARE Metastatic Breast Cancer
3 years ago
Letrozole/Tamoxifen and Ablation
Understand
Tamoxifen
has similar reactions. Hard to get cardiologists to acknowledge connection but its definitely there in my case. Now starting to think this created AFib in first place.
Understand
Tamoxifen
has similar reactions. Hard to get cardiologists to acknowledge connection but its definitely there in my case. Now starting to think this created AFib in first place.
SilverliningsForNow
in
AF Association
3 years ago
Yearly scanxiety :(
Then 2020 we found out she had BC and that was also removed and only followed by
tamoxifen
and some radiation. She has had yearly PET scans since 2019 and they have been clear so far thankfully. She got her yearly one last Tuesday, and we have not heard back from the oncologist.
Then 2020 we found out she had BC and that was also removed and only followed by
tamoxifen
and some radiation. She has had yearly PET scans since 2019 and they have been clear so far thankfully. She got her yearly one last Tuesday, and we have not heard back from the oncologist.
janeths466
in
Lung Cancer Support
3 years ago
Scanxiety Headaches
She does suffer from high blood pressure w the dyalisis and is on
tamoxifen
, which could be part of the problem, but my brain goes to the worst case scenario and I hate it. I am 23 and have bad anxiety, I am very scared for the next weeks and results.
She does suffer from high blood pressure w the dyalisis and is on
tamoxifen
, which could be part of the problem, but my brain goes to the worst case scenario and I hate it. I am 23 and have bad anxiety, I am very scared for the next weeks and results.
janeths466
in
SHARE Metastatic Breast Cancer
3 years ago
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