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Small lymphocytic lymphoma (SLL)
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Diptheria Immunotoxin Effectively Targets B-Cell Malignancies - Phase 1 trial of DT2219
[i]"Dr. Vallera and colleagues enrolled 25 chemo-refractory patients with previously treated pre-B acute lymphoblastic leukemia, chronic lymphocytic leukemia, or non-Hodgkin lymphoma whose tumors expressed CD19 and/or CD22. Eight patients had previously undergone unsuccessful bone marrow transplantations
[i]"Dr. Vallera and colleagues enrolled 25 chemo-refractory patients with previously treated pre-B acute lymphoblastic leukemia, chronic lymphocytic leukemia, or non-Hodgkin lymphoma whose tumors expressed CD19 and/or CD22. Eight patients had previously undergone unsuccessful bone marrow transplantations
AussieNeil
Partner
in
CLL Support
9 years ago
NCI Director Resigns
NCI Director Harold Varmus Resigns Author: Silas Inman Dr. Harold Varmus Harold Varmus, MD The Nobel Prize winning director of the National Cancer Institute (NCI), Harold Varmus, MD, has tendered his resignation in a letter to President Barack Obama, citing economic restraints as a leading cause for
NCI Director Harold Varmus Resigns Author: Silas Inman Dr. Harold Varmus Harold Varmus, MD The Nobel Prize winning director of the National Cancer Institute (NCI), Harold Varmus, MD, has tendered his resignation in a letter to President Barack Obama, citing economic restraints as a leading cause for
Justasheet1
in
CLL Support
9 years ago
Has anyone had eight months of treatment using Rituxan and Treanda (bendamustine)
Has anyone had eight months of treatment using Rituxan and Treanda (bendamustine) instead of the manufacture recommendation of six months? If yes, did you get longer remission time? History: CLL diagnosed in 2004. On W&W until October 2007. Treatment began using Leukkeran (chlorambucil) dexamethasone
Has anyone had eight months of treatment using Rituxan and Treanda (bendamustine) instead of the manufacture recommendation of six months? If yes, did you get longer remission time? History: CLL diagnosed in 2004. On W&W until October 2007. Treatment began using Leukkeran (chlorambucil) dexamethasone
Janetfld
in
CLL Support
9 years ago
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just diagnosed from a blood test done in 2009
Hi im 58yrs old I was diagnosed at first with Non Hodgkins Lymphoma after a breast screening 10 days later I saw a Haematologist that said from a bood test in 2009 ( no follow up on by my doctors) and the biopsy I had take from nodes in my arm pits 5 weeks ago I have CLL . I was trying to get my head
Hi im 58yrs old I was diagnosed at first with Non Hodgkins Lymphoma after a breast screening 10 days later I saw a Haematologist that said from a bood test in 2009 ( no follow up on by my doctors) and the biopsy I had take from nodes in my arm pits 5 weeks ago I have CLL . I was trying to get my head
mush56
in
CLL Support
9 years ago
The Emperor of All Maladies - PBS documentary
LLS newsletter I received announced an upcoming documentary based on the renown primer on cancer. ******** Found a blurb and a PBS link with trailer: "Siemens proudly supports "Cancer: The Emperor of All Maladies,” a film based on The Emperor of All Maladies: A Biography of Cancer by Pulitzer Prize-winning
LLS newsletter I received announced an upcoming documentary based on the renown primer on cancer. ******** Found a blurb and a PBS link with trailer: "Siemens proudly supports "Cancer: The Emperor of All Maladies,” a film based on The Emperor of All Maladies: A Biography of Cancer by Pulitzer Prize-winning
gemit2000
in
CLL Support
9 years ago
Can Your Body Be Trained to Cure Its Own Cancer?
Another one about immunotherapy: For decades, cancer patients have been limited to a trio of treatment options. While surgery, chemotherapy and radiation have their effectiveness, they also have serious drawbacks that can compromise quality of life. Continued research in the area of immunotherapy is
Another one about immunotherapy: For decades, cancer patients have been limited to a trio of treatment options. While surgery, chemotherapy and radiation have their effectiveness, they also have serious drawbacks that can compromise quality of life. Continued research in the area of immunotherapy is
shazie
in
CLL Support
9 years ago
Is It Me Or Today's Society
Hey guys I just wanted to share with you guys that have me appointment for my first Rituximab Infusion next week. And the first thing I randomly thought was dose the Kings College Chemotherapy Day Unit have free Wifi I don’t know if that says something about me or today’s society God forbid I go a
Hey guys I just wanted to share with you guys that have me appointment for my first Rituximab Infusion next week. And the first thing I randomly thought was dose the Kings College Chemotherapy Day Unit have free Wifi I don’t know if that says something about me or today’s society God forbid I go a
wotshernameagain
in
LUPUS UK
9 years ago
Imbruvica is on track to be a top seller for J&J and Pharmacyclics for years to come
Interesting insight into the revenues of the best selling cancer drugs in the USA. Many are familiar to us; Imbruvica of course and Revlimid (Lenalidomide), Rituxan (Rituximab/Mabthera) and perhaps Gleevec (Imatinib), the drug that did for CML what we are still looking for with CLL. http://www.fool.com
Interesting insight into the revenues of the best selling cancer drugs in the USA. Many are familiar to us; Imbruvica of course and Revlimid (Lenalidomide), Rituxan (Rituximab/Mabthera) and perhaps Gleevec (Imatinib), the drug that did for CML what we are still looking for with CLL. http://www.fool.com
AussieNeil
Partner
in
CLL Support
9 years ago
Can anyone confirm if Ibrutinib is now available on prescription in the UK?
I just received an email from a friend to suggest it is available. I’m to start 6 months of BR treatment on Monday 12th January, and would be so relieved if I can try a non-chemotherapy drug instead. Dear Healthcare Professional I am pleased to inform you that Janssen UK has been granted European Medicines
I just received an email from a friend to suggest it is available. I’m to start 6 months of BR treatment on Monday 12th January, and would be so relieved if I can try a non-chemotherapy drug instead. Dear Healthcare Professional I am pleased to inform you that Janssen UK has been granted European Medicines
Ruhi9
in
CLL Support
9 years ago
New approach could lead cancer cells down path of destruction
Cancer research has discovered that when double-strand break DNA damage occurs, in which both strands of the DNA double helix are severed, the cell can either attempt to repair the damage, which has a poor chance of success and may create a cancerous cell (or a more aggressive clone of an existing cancerous
Cancer research has discovered that when double-strand break DNA damage occurs, in which both strands of the DNA double helix are severed, the cell can either attempt to repair the damage, which has a poor chance of success and may create a cancerous cell (or a more aggressive clone of an existing cancerous
AussieNeil
Partner
in
CLL Support
9 years ago
Blood counts very poor, soon to start BR, and unsure whether to have jabs? (See later post)
Hi everyone, Thanks for all your responses to my post 3 weeks ago. The blood test results on 10th December were confusing to say the least - WBC had increased from 81.6 to 123.5 since the previous tests at the end of November, while neutrophils, HB and platelets were all improved. My consultant was
Hi everyone, Thanks for all your responses to my post 3 weeks ago. The blood test results on 10th December were confusing to say the least - WBC had increased from 81.6 to 123.5 since the previous tests at the end of November, while neutrophils, HB and platelets were all improved. My consultant was
Ruhi9
in
CLL Support
10 years ago
Long-Term Data for Zydelig (idelalisib) from ASH2014
Skip down to the section titled
Long-Term Data in CLL
, Includes information on Study 116/117 and the boxed warning (safety information) for idelalisib: http://www.finances.com/company-news/44331-gilead-presents-follow-up-data-from-zydelig-registrational-studies-in-patients-with-chronic-
lymphocytic
-leukemia-follicular-
lymphoma
-and-
small
-
lymphocytic
-lymphoma.htm
Skip down to the section titled
Long-Term Data in CLL
, Includes information on Study 116/117 and the boxed warning (safety information) for idelalisib: http://www.finances.com/company-news/44331-gilead-presents-follow-up-data-from-zydelig-registrational-studies-in-patients-with-chronic-
lymphocytic
-leukemia-follicular-
lymphoma
-and-
small
-
lymphocytic
-lymphoma.htm
AussieNeil
Partner
in
CLL Support
10 years ago
Bone marrow Abnormalities and APS
Hi Just wondering if there is a link between bone marrow abnormalities and APS? I had a bone marrow biopsy at my local hospital and it has shown abnormalities in mast cells, chromasomes . . . I have been referred to Kings for another biopsy for specialised testing. Does anyone else have bone marrow abnormalities
Hi Just wondering if there is a link between bone marrow abnormalities and APS? I had a bone marrow biopsy at my local hospital and it has shown abnormalities in mast cells, chromasomes . . . I have been referred to Kings for another biopsy for specialised testing. Does anyone else have bone marrow abnormalities
beckyb
in
Hughes Syndrome APS Forum
10 years ago
Husband suffering from mantle cell lymphoma
I just wanted to find out what should one do to regain strength after the chemotherapy. My husband is completely drained out after his third chemotherapy. How should it be dealt with?
I just wanted to find out what should one do to regain strength after the chemotherapy. My husband is completely drained out after his third chemotherapy. How should it be dealt with?
kk055
in
Cancer Patients Aid Association India
10 years ago
TG Therapeutics announces Clinical Trial of TGR-1202 in combination with Ibrutinib
TG Therapeutics, Inc. announced today the initiation of a multi-center, Phase I trial to evaluate the safety and efficacy of the combination of TGR-1202 and ibrutinib for patients with relapsed and/or refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL): http://money.cnn.com/news
TG Therapeutics, Inc. announced today the initiation of a multi-center, Phase I trial to evaluate the safety and efficacy of the combination of TGR-1202 and ibrutinib for patients with relapsed and/or refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL): http://money.cnn.com/news
AussieNeil
Partner
in
CLL Support
10 years ago
Extended Rituximab Plus R-CHOP Best in Elderly, Poor-Prognosis DLBCL
[i]"Elderly patients with poor-prognosis diffuse large B-cell lymphoma (DLBCL) may derive the most benefit from treatment with extended rituximab plus 6 cycles of R-CHOP on a 14-day schedule, according to the results of the SMARTE-R study published in the Journal of Clinical Oncology."[/i] http://www.cancernetwork.com
[i]"Elderly patients with poor-prognosis diffuse large B-cell lymphoma (DLBCL) may derive the most benefit from treatment with extended rituximab plus 6 cycles of R-CHOP on a 14-day schedule, according to the results of the SMARTE-R study published in the Journal of Clinical Oncology."[/i] http://www.cancernetwork.com
AussieNeil
Partner
in
CLL Support
10 years ago
Global burden of cancer attributable to high body-mass index
High body-mass index (BMI; defined as 25 kg/m2 or greater) is associated with increased risk of cancer. To inform public health policy and future research, we estimated the global burden of cancer attributable to high BMI in 2012. http://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(14)71123
High body-mass index (BMI; defined as 25 kg/m2 or greater) is associated with increased risk of cancer. To inform public health policy and future research, we estimated the global burden of cancer attributable to high BMI in 2012. http://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(14)71123
shazie
in
CLL Support
10 years ago
Tinzaparin
Hi everybody, haven't been on here for a while because I'm busy looking after my mother who lives 60 miles away.quite a journey two or three times per week. Anyway I've been on tinzaparin injections for two months now and wondered how long I can stay on this drug. I don't particularly fancy going onto
Hi everybody, haven't been on here for a while because I'm busy looking after my mother who lives 60 miles away.quite a journey two or three times per week. Anyway I've been on tinzaparin injections for two months now and wondered how long I can stay on this drug. I don't particularly fancy going onto
Elfie1
in
Hughes Syndrome APS Forum
10 years ago
Rituximab question
Hi everyone. Have the appointment for my first and second dose of rituximab come through today for 9th and 23rd of December. 2 days before my birthday and two days before Christmas. Just wanted to know if the medicine can wipe you out after infusion and if anyone has experienced this, worried I will
Hi everyone. Have the appointment for my first and second dose of rituximab come through today for 9th and 23rd of December. 2 days before my birthday and two days before Christmas. Just wanted to know if the medicine can wipe you out after infusion and if anyone has experienced this, worried I will
joannebond360
in
LUPUS UK
10 years ago
Fast Chemo (Bendamustine in 10 minutes)
Eagle Pharmaceuticals have just announced the success of a Phase 1 trial of 81 patients, which has shown that a 50ml admixture of Bendamustine HCl delivered in ten minutes (their rapidly infused product) was found to be bioequivalent to the Treanda 500mL admixture, which requires a 60-minute infusion
Eagle Pharmaceuticals have just announced the success of a Phase 1 trial of 81 patients, which has shown that a 50ml admixture of Bendamustine HCl delivered in ten minutes (their rapidly infused product) was found to be bioequivalent to the Treanda 500mL admixture, which requires a 60-minute infusion
AussieNeil
Partner
in
CLL Support
10 years ago
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