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Ritonavir
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"Oral Nirmatrelvir–Ritonavir [ Paxlovid ] as Postexposure Prophylaxis for Covid-19" -- does not do much
In this placebo-controlled trial, postexposure prophylaxis with nirmatrelvir-
ritonavir
for 5 or 10 days
did not significantly reduce the risk of symptomatic SARS-CoV-2 infection
." [That sort of has been the suspicion since the very beginning.]
In this placebo-controlled trial, postexposure prophylaxis with nirmatrelvir-
ritonavir
for 5 or 10 days
did not significantly reduce the risk of symptomatic SARS-CoV-2 infection
." [That sort of has been the suspicion since the very beginning.]
70s-80s-overlander
in
CLL Support
1 month ago
SARS-CoV-2 Virologic Rebound With Nirmatrelvir–Ritonavir Therapy - An Observational Study, Annals of Internal Medicine, 14 November 2023.
Full access link to the paper: [i]
SARS-CoV-2 Virologic Rebound With Nirmatrelvir–
Therapy - An Observational Study, Annals of Internal Medicine, Original Research, 14 November 2023.
Full access link to the paper: [i]
SARS-CoV-2 Virologic Rebound With Nirmatrelvir–
Therapy - An Observational Study, Annals of Internal Medicine, Original Research, 14 November 2023.
cujoe
in
CLL Support
9 months ago
Info re drug interactions with Paxlovid
https://www.covid19treatmentguidelines.nih.gov/therapies/antivirals-including-antibody-products/
ritonavir
-boosted-nirmatrelvir--paxlovid-/paxlovid-drug-drug-interactions/ Hi All - Inresponse to my two responses I found this from NIH which states that Prednisone and other drugs are safe with Paxlovid
https://www.covid19treatmentguidelines.nih.gov/therapies/antivirals-including-antibody-products/
ritonavir
-boosted-nirmatrelvir--paxlovid-/paxlovid-drug-drug-interactions/ Hi All - Inresponse to my two responses I found this from NIH which states that Prednisone and other drugs are safe with Paxlovid
bluegirl7
in
PMRGCAuk
1 year ago
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Paxlovid and Lagevrio Benefit COVID Outpatients in Omicron Era September 19, 2023
src=rss ) : [i]Consider the oral antivirals nirmatrelvir-
ritonavir
(Paxlovid) or molnupiravir (Lagevrio) for symptomatic outpatients with confirmed mild to moderate COVID-19 who are within 5 days of the onset of symptoms and at high risk for progressing to severe disease and potential hospitalization
src=rss ) : [i]Consider the oral antivirals nirmatrelvir-
ritonavir
(Paxlovid) or molnupiravir (Lagevrio) for symptomatic outpatients with confirmed mild to moderate COVID-19 who are within 5 days of the onset of symptoms and at high risk for progressing to severe disease and potential hospitalization
lankisterguy
Volunteer
in
CLL Support
11 months ago
Study suggests Paxlovid is effective against the Omicron variant in over 65s
query=TOC&cid=NEJM%20eToc,%20August%2025,%202022%20DM1379474_NEJM_Non_Subscriber&bid=1131122421 looked at "Nirmatrelvir Use and Severe Covid-19 Outcomes during the Omicron Surge" in Israel, while elsewhere Nirmatrelivir is authorised to be given with
Ritonavir
, the two oral antivirals being co-packaged
query=TOC&cid=NEJM%20eToc,%20August%2025,%202022%20DM1379474_NEJM_Non_Subscriber&bid=1131122421 looked at "Nirmatrelvir Use and Severe Covid-19 Outcomes during the Omicron Surge" in Israel, while elsewhere Nirmatrelivir is authorised to be given with
Ritonavir
, the two oral antivirals being co-packaged
bennevisplace
in
CLL Support
2 years ago
EvuSheld in the Uk
This could be either sotrovimab or nirmatrelvir with
ritonavir
(Paxlovid), and those who are unable to receive these treatments will be offered remdesivir (Veklury) and then molnupiravir.
This could be either sotrovimab or nirmatrelvir with
ritonavir
(Paxlovid), and those who are unable to receive these treatments will be offered remdesivir (Veklury) and then molnupiravir.
Me2AsWell
in
CLL Support
2 years ago
Refused treatment.
I registered my condition with all the relevant departments and awaited a phone call from a doctor to assess my condition with the view to being offered one of the new treatments, (Nirmatrelvir,
Ritonavir
, Remdesivir, or Molnupiravir) because I am clinically extremely vulnerable.
I registered my condition with all the relevant departments and awaited a phone call from a doctor to assess my condition with the view to being offered one of the new treatments, (Nirmatrelvir,
Ritonavir
, Remdesivir, or Molnupiravir) because I am clinically extremely vulnerable.
Willmebe
in
Vasculitis UK
2 years ago
COVID update: Who remains at higher risk? by LLS.org
Antiviral medications Paxlovid™ (nirmatrelvir/
ritonavir
), Legevrio™ (molnupiravir), and Veklury® (remdesivir) remain active against currently circulating COVID virus subvariants.
Antiviral medications Paxlovid™ (nirmatrelvir/
ritonavir
), Legevrio™ (molnupiravir), and Veklury® (remdesivir) remain active against currently circulating COVID virus subvariants.
lankisterguy
Volunteer
in
CLL Support
2 years ago
COVID: Staying Safe As The Virus Evolves - LLS Podcast / CLL Society’s COVID-19 Update December 5th, 2022 / Dec 15 2022 end Antibody Study
Antiviral medications Paxlovid™ (nirmatrelvir/
ritonavir
), Legevrio™ (molnupiravir), and Veklury® (remdesivir) remain active against currently circulating COVID virus subvariants.
Antiviral medications Paxlovid™ (nirmatrelvir/
ritonavir
), Legevrio™ (molnupiravir), and Veklury® (remdesivir) remain active against currently circulating COVID virus subvariants.
lankisterguy
Volunteer
in
CLL Support
2 years ago
COVID-19 Treatments for Higher Risk Individuals - UPDATED 15/02/2022
2.Nirmatrelvir and
(Paxlovid) has been added as a first-line COVID-19 treatment In many cases, Paxlovid will be offered instead of the antibody infusion, sotrovimab. Paxlovid is an oral treatment meaning that it can be taken without having to attend a hospital.
2.Nirmatrelvir and
(Paxlovid) has been added as a first-line COVID-19 treatment In many cases, Paxlovid will be offered instead of the antibody infusion, sotrovimab. Paxlovid is an oral treatment meaning that it can be taken without having to attend a hospital.
Paul_Howard
LUPUS UK
in
LUPUS UK
3 years ago
New COVID pill Paxlovid contraindicated with apalutamide
This is from the FDA fact sheet- PAXLOVID is contraindicated with drugs that are potent CYP3A inducers where significantly reduced nirmatrelvir or
ritonavir
plasma concentrations may be associated with the potential for loss of virologic response and possible resistance.
This is from the FDA fact sheet- PAXLOVID is contraindicated with drugs that are potent CYP3A inducers where significantly reduced nirmatrelvir or
ritonavir
plasma concentrations may be associated with the potential for loss of virologic response and possible resistance.
V10fanatic
in
Advanced Prostate Cancer
3 years ago
Pfizer antiviral Covid-19 tablet “Paxlovid” a word of caution
Careful monitoring of therapeutic and adverse effects is recommended when these medicines are concomitantly administered with
ritonavir
.
Careful monitoring of therapeutic and adverse effects is recommended when these medicines are concomitantly administered with
ritonavir
.
Richard-Allen
in
British Liver Trust
3 years ago
Important SARS-CoV-2 and Covid-19 information for Chronic Lymphocytic Leukaemia/CLL patients
responses=147645398 [u]
Drug-Drug Interactions Between
-Boosted Nirmatrelvir (Paxlovid) and Concomitant Medications:[/u]
https://www.covid19treatmentguidelines.nih.gov/therapies/antiviral-therapy/
ritonavir
-boosted-nirmatrelvir--paxlovid-/paxlovid-drug-drug-interactions/ [u]
Management
responses=147645398 [u]
Drug-Drug Interactions Between
-Boosted Nirmatrelvir (Paxlovid) and Concomitant Medications:[/u]
https://www.covid19treatmentguidelines.nih.gov/therapies/antiviral-therapy/
ritonavir
-boosted-nirmatrelvir--paxlovid-/paxlovid-drug-drug-interactions/ [u]
Management
CLLerinOz
Administrator
in
CLL Support
3 years ago
UK Government announce that supplies of Molnupiravir and Ritonavir against Covid 19 have been secured.
Thousands of vulnerable patients could be taking ground-breaking COVID-19 antivirals this winter after the government announced deals to secure 2 new treatments. These treatments should speed up recovery time for COVID-19 patients and the most vulnerable will be eligible first, including the elderly
Thousands of vulnerable patients could be taking ground-breaking COVID-19 antivirals this winter after the government announced deals to secure 2 new treatments. These treatments should speed up recovery time for COVID-19 patients and the most vulnerable will be eligible first, including the elderly
Jm954
Administrator
in
CLL Support
3 years ago
Oral chemo
Initially, 30 mg of ModraDoc006 combined with 200 mg of
ritonavir
in the morning and 20 mg of ModraDoc006 with 100 mg of
ritonavir
in the evening were administered on days 1, 8, and 15 of the 21-day cycle.
Initially, 30 mg of ModraDoc006 combined with 200 mg of
ritonavir
in the morning and 20 mg of ModraDoc006 with 100 mg of
ritonavir
in the evening were administered on days 1, 8, and 15 of the 21-day cycle.
podsart
in
Advanced Prostate Cancer
3 years ago
Covid-19 CT update: Good News from Hong Kong Phase 2 Triple Combination. Source: Lancet
A triple-antiviral therapy regimen of interferon-beta1, lopinavir/
ritonavir
, and ribavirin shortened median time to COVID-19 viral negativity (mild to moderate cohorts) in a small, randomized trial (n=84) done by the University of Hong Kong (China).
A triple-antiviral therapy regimen of interferon-beta1, lopinavir/
ritonavir
, and ribavirin shortened median time to COVID-19 viral negativity (mild to moderate cohorts) in a small, randomized trial (n=84) done by the University of Hong Kong (China).
sharoncrayn
in
Cure Parkinson's
4 years ago
World's largest trial of potential Coronavirus treatments being rolled out across the UK - RECOVERY Trial
They include: Lopinavir-
Ritonavir
, commonly used to treat HIV Dexamethasone, a type of steroid use in a range of conditions to reduce inflammation Hydroxychloroquine, a treatment for malaria The trial is being conducted in over 130 NHS hospitals across the UK.
They include: Lopinavir-
Ritonavir
, commonly used to treat HIV Dexamethasone, a type of steroid use in a range of conditions to reduce inflammation Hydroxychloroquine, a treatment for malaria The trial is being conducted in over 130 NHS hospitals across the UK.
Jm954
Administrator
in
CLL Support
4 years ago
European clinical trial starts on possible coronavirus treatments.
The four treatments to be studied are remdesivir, lopinavir and
ritonavir
in combination, the latter being administered with or without interferon beta and hydroxychloroquine, French public health research body Inserm said in a statement on Sunday.
The four treatments to be studied are remdesivir, lopinavir and
ritonavir
in combination, the latter being administered with or without interferon beta and hydroxychloroquine, French public health research body Inserm said in a statement on Sunday.
2greys
in
Lung Conditions Community Forum
4 years ago
COVID 19 Facts you may not know - for EU citizens
SOLIDARITY is examining four promising drug regimens: 1) Remdesivir—an experimental antiviral medication; 2) Chloroquine and hydroxychloroquine—malaria medications; 3) Lopinavir and
ritonavir
—two HIV drugs that may be useful in combination; and 4) Lopinavir,
ritonavir
plus interferon-beta, a medication
SOLIDARITY is examining four promising drug regimens: 1) Remdesivir—an experimental antiviral medication; 2) Chloroquine and hydroxychloroquine—malaria medications; 3) Lopinavir and
ritonavir
—two HIV drugs that may be useful in combination; and 4) Lopinavir,
ritonavir
plus interferon-beta, a medication
hunter5582
in
MPN Voice
4 years ago
Coronavirus drugs: Where we are and what we know
Ritonavir
helps boost lopinavir's concentrations in cells. Scientists wondered whether the pair might be able to disrupt SARS-COV-2's life cycle in similar ways. But a study published this week in the New England Journal of Medicine reported no benefit for patients with severe COVID-19.
Ritonavir
helps boost lopinavir's concentrations in cells. Scientists wondered whether the pair might be able to disrupt SARS-COV-2's life cycle in similar ways. But a study published this week in the New England Journal of Medicine reported no benefit for patients with severe COVID-19.
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
4 years ago
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