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Non metastasis castrate resistant
When you are on ADT and become Non metastatic Castrate resistant and your testosterone levels are below zero, what is the cancer feeding off to cause the PSA to still rise? Hoping for your replies so as to give me some understanding. Thank you.
When you are on ADT and become Non metastatic Castrate resistant and your testosterone levels are below zero, what is the cancer feeding off to cause the PSA to still rise? Hoping for your replies so as to give me some understanding. Thank you.
Sailameme
in
Advanced Prostate Cancer
5 months ago
low levels of T4 & T3 on 3 grains of NDT
Dear all, Again I need some help with my blood tests interpretation and further steps. I’m currently on 3 grains of thyroid-s and my results are as shown on the table below. Both FT3 & FT4 levels are not satisfactory. Could this be because of the low levels of ferritin, D3 and B12? Or do I need to
Dear all, Again I need some help with my blood tests interpretation and further steps. I’m currently on 3 grains of thyroid-s and my results are as shown on the table below. Both FT3 & FT4 levels are not satisfactory. Could this be because of the low levels of ferritin, D3 and B12? Or do I need to
selenipap
in
Thyroid UK
5 months ago
bit lost - sw cornwall company /accom needed
so. In keeping with my 7 yr uk nightmare no sooner than I had NDT, house packed/ cash buyer water began pouring thru roof 😭😭😭. Looks like I’m stuck here a few more months. spent a couple nights in b&b only to come home and realise how awful 6 yrs living on a building site is (during 1 yr of rental
so. In keeping with my 7 yr uk nightmare no sooner than I had NDT, house packed/ cash buyer water began pouring thru roof 😭😭😭. Looks like I’m stuck here a few more months. spent a couple nights in b&b only to come home and realise how awful 6 yrs living on a building site is (during 1 yr of rental
joydot
in
Thyroid UK
5 months ago
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Increasing Gut Issues
Hiya.I am currently having increasing gut type issues with my current batch of NDT. When I increase the dose, which I need to for my levels to be optimum, I am getting increased belly swelling, painful trapped wind which runs from my throat down my oesophagus and abdomen. The last few days, my belly
Hiya.I am currently having increasing gut type issues with my current batch of NDT. When I increase the dose, which I need to for my levels to be optimum, I am getting increased belly swelling, painful trapped wind which runs from my throat down my oesophagus and abdomen. The last few days, my belly
MindfulMoments
in
Thyroid UK
5 months ago
Sourcing THYROID-S NDT
I am coming to the end of my supply of Thyroid-S NDT.It is batch no.TA21089,expiry date 12.24. From reading posts on here,I can see there are now supply issues. Been through this before with THIROID then TR Mann over the years . Please pm me reliable functional supplier information.
I am coming to the end of my supply of Thyroid-S NDT.It is batch no.TA21089,expiry date 12.24. From reading posts on here,I can see there are now supply issues. Been through this before with THIROID then TR Mann over the years . Please pm me reliable functional supplier information.
Naomi8
in
Thyroid UK
5 months ago
Just some new Information about AI
Came across this article a couple days ago. https://www.news-medical.net/news/20210924/Researchers-identify-two-subtypes-of-metastatic-prostate-cancer.aspx#:~:text=Building%20off%20of%20earlier%20studies%20that%20discovered%20clinically,into%20two%20types%20known%20as%20luminal%20and%20basal AI has
Came across this article a couple days ago. https://www.news-medical.net/news/20210924/Researchers-identify-two-subtypes-of-metastatic-prostate-cancer.aspx#:~:text=Building%20off%20of%20earlier%20studies%20that%20discovered%20clinically,into%20two%20types%20known%20as%20luminal%20and%20basal AI has
chefjlu
in
Advanced Prostate Cancer
5 months ago
Revised Plot of PSA vs Testosterone: Estrogen vs Lupron ADT
Ugh...I made a BIG mistake on the previous posting! I just realized that Dr. Morgentaler had listed the Testosterone level in unusual units (
ng/mL
), not the usual units of (
ng/dL)
. So, my X-axis was off by a factor of 10. Here is the revised plot. The exciting discovery is that the
Ugh...I made a BIG mistake on the previous posting! I just realized that Dr. Morgentaler had listed the Testosterone level in unusual units (
ng/mL
), not the usual units of (
ng/dL)
. So, my X-axis was off by a factor of 10. Here is the revised plot. The exciting discovery is that the
janebob99
in
Advanced Prostate Cancer
5 months ago
Morgentaler Saturation Model: PSA vs Testosterone - Estrogen Patch vs Lupron ADT
This is a plot of % reduction in PSA from a Maximum Value versus Testosterone, for two different datasets: Estrogen Patch and Lupron ADT. Both curves (red and green lines) show a linear response starting from (0,0), up to about 200-250 ng/dL. Then, the lines curve over to a lower slope (especially
This is a plot of % reduction in PSA from a Maximum Value versus Testosterone, for two different datasets: Estrogen Patch and Lupron ADT. Both curves (red and green lines) show a linear response starting from (0,0), up to about 200-250 ng/dL. Then, the lines curve over to a lower slope (especially
janebob99
in
Advanced Prostate Cancer
5 months ago
Another brother passes
My friend, George, passed this morning after a two year battle. He was DX'd at 85 with prostate cancer (PSA of 1200) behind his eye which spread to his brain. Failed ADT, chemo and Pluvicto. He was not on this forum. He was very active, skied 120 days a year, biked the rest. He and his wife went to
My friend, George, passed this morning after a two year battle. He was DX'd at 85 with prostate cancer (PSA of 1200) behind his eye which spread to his brain. Failed ADT, chemo and Pluvicto. He was not on this forum. He was very active, skied 120 days a year, biked the rest. He and his wife went to
gsun
in
Advanced Prostate Cancer
5 months ago
PSMA Scan to be scheduled - thank you Tall Allen
I want to thank Tall Allen for his suggestion that I see an oncologist. I had a RP followed by radiation in 2013. My PSA was undetectable until 2021, when it started to rise. This week I saw a radiation oncologist (whom I found through a friend) to ask him a lot of questions and to get his advice.
I want to thank Tall Allen for his suggestion that I see an oncologist. I had a RP followed by radiation in 2013. My PSA was undetectable until 2021, when it started to rise. This week I saw a radiation oncologist (whom I found through a friend) to ask him a lot of questions and to get his advice.
Geno2853
in
Advanced Prostate Cancer
5 months ago
PSA-Nadir vs Testosterone-Nadir comparing Non-CRPC to CRPX men
These plots show the linear relationship between median PSA-Nadir and median Testosterone-Nadir, pointing towards the Origin (i.e., 0 PSA-Nadir at 0 T-Nadir.). N= 38 men. The upper to graphs compare median PSA-nadir and median T-Nadir for Non-CRPC and CPRC groups (CPRC = Castrate Resistant Prostate
These plots show the linear relationship between median PSA-Nadir and median Testosterone-Nadir, pointing towards the Origin (i.e., 0 PSA-Nadir at 0 T-Nadir.). N= 38 men. The upper to graphs compare median PSA-nadir and median T-Nadir for Non-CRPC and CPRC groups (CPRC = Castrate Resistant Prostate
janebob99
in
Advanced Prostate Cancer
5 months ago
PSA-Nadir vs Testosterone-Nadir
These plots show the linear relationship between median PSA-Nadir and median Testosterone-Nadir, pointing towards the Origin (i.e., 0 PSA-Nadir at 0 T-Nadir.). N= 38 men. The upper to graphs compare median PSA-nadir and median T-Nadir for Non-CRPC and CPRC groups (CPRC = Castrate Resistant Prostate
These plots show the linear relationship between median PSA-Nadir and median Testosterone-Nadir, pointing towards the Origin (i.e., 0 PSA-Nadir at 0 T-Nadir.). N= 38 men. The upper to graphs compare median PSA-nadir and median T-Nadir for Non-CRPC and CPRC groups (CPRC = Castrate Resistant Prostate
janebob99
in
Prostate Cancer Network
5 months ago
T3 only worth another PROPER go?
Okay so I made a post last year about being unable tolerate t3 only but I’m actually wondering if I jumped onto t3 mono too quickly and gave up too fast? (Which many others pointed out but at the time I was so unwell I could barely think straight) Prior to starting T3 only back then I was on a too
Okay so I made a post last year about being unable tolerate t3 only but I’m actually wondering if I jumped onto t3 mono too quickly and gave up too fast? (Which many others pointed out but at the time I was so unwell I could barely think straight) Prior to starting T3 only back then I was on a too
GreenTealSeal
in
Thyroid UK
5 months ago
Recommendations for NDT without prescription
Hello everyone, In looking to buy NDT without prescription. I used to be on erfa before I moved back to UK and since I've been here, I have been on levo and it's not working well for me. I'd very much appreciate recommendations via PM. Thank you so much.
Hello everyone, In looking to buy NDT without prescription. I used to be on erfa before I moved back to UK and since I've been here, I have been on levo and it's not working well for me. I'd very much appreciate recommendations via PM. Thank you so much.
Jenyren
in
Thyroid UK
5 months ago
ADT response and questions for MO
Hi, I am newish to this forum, still on a steep learning curve but I want to thank you for your contributions and discussions. This is my first time posting. My partner is 60 yrs old, as I understand it he had low PSA 3 yrs ago, not tested until Nov 2023, PSA50, stage 4, 1 met in 'sit' bone. Started
Hi, I am newish to this forum, still on a steep learning curve but I want to thank you for your contributions and discussions. This is my first time posting. My partner is 60 yrs old, as I understand it he had low PSA 3 yrs ago, not tested until Nov 2023, PSA50, stage 4, 1 met in 'sit' bone. Started
Lovecherries
in
Advanced Prostate Cancer
5 months ago
One questions doctors never seem to be able to answer is at what PSA level do you start to experience pain or physical problems?
One questions doctors never seem to be able to answer is at what PSA level do you start to experience pain or physical problems? If you have had surgery, Salvage Radiation, ADT, SRBT and then stopped ADT with a continuing rise in you PSA when did you start to have pain or physical problems?
One questions doctors never seem to be able to answer is at what PSA level do you start to experience pain or physical problems? If you have had surgery, Salvage Radiation, ADT, SRBT and then stopped ADT with a continuing rise in you PSA when did you start to have pain or physical problems?
Exrunner
in
Advanced Prostate Cancer
5 months ago
New study validates intermittent hormone therapy
PCRI just posted a new video titled 'New study validates intermittent hormone therapy'. So, just search 'PCRI' in YouTube and that video will pop up. Certain individuals on this site feel strongly against curtailing the duration of hormone therapy from the standard 2 to 3 years or even longer. I urge
PCRI just posted a new video titled 'New study validates intermittent hormone therapy'. So, just search 'PCRI' in YouTube and that video will pop up. Certain individuals on this site feel strongly against curtailing the duration of hormone therapy from the standard 2 to 3 years or even longer. I urge
John347
in
Advanced Prostate Cancer
5 months ago
ARASENS Darolutamide vs Placebo
This Kaplan-Meier plot show the Castration - Resistant Prostate Cancer Free survival probability (%) for two groups: (A)
Darolutamide
+ ADT + Docetaxel, versus (B)
Placebo
+ ADT + Docetaxel, taken at two different times: 2 years and 4 years. There is a very large increase in survival
This Kaplan-Meier plot show the Castration - Resistant Prostate Cancer Free survival probability (%) for two groups: (A)
Darolutamide
+ ADT + Docetaxel, versus (B)
Placebo
+ ADT + Docetaxel, taken at two different times: 2 years and 4 years. There is a very large increase in survival
janebob99
in
Advanced Prostate Cancer
5 months ago
ARASENS TRIAL: Darolutamide
This Kaplan-Mieir plot show the Castration - Resistant Prostate Cancer Free survival probability (%) vs time for two groups: (A) Darolutamide + ADT + Docetaxel, versus (B) Placebo + ADT + Docetaxel. There is a very large increase in survival probability with the Darolutamide group (A) vs Placebo group
This Kaplan-Mieir plot show the Castration - Resistant Prostate Cancer Free survival probability (%) vs time for two groups: (A) Darolutamide + ADT + Docetaxel, versus (B) Placebo + ADT + Docetaxel. There is a very large increase in survival probability with the Darolutamide group (A) vs Placebo group
janebob99
in
Advanced Prostate Cancer
5 months ago
ADT with radiation?
I have a G 4+3, considered to be unfavorable intermediate risk, but a Decipher score of .4, considered to be low risk. I have opted to have radiation to treat my PCa. Do I need to take ADT with the radiation therapy? My MO suggested 4 to 6 months of Orgavix (not sure if I'm spelling it correctly). If
I have a G 4+3, considered to be unfavorable intermediate risk, but a Decipher score of .4, considered to be low risk. I have opted to have radiation to treat my PCa. Do I need to take ADT with the radiation therapy? My MO suggested 4 to 6 months of Orgavix (not sure if I'm spelling it correctly). If
CBRD
in
Advanced Prostate Cancer
5 months ago
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