Experiences with

Pyridostigmine

I have been refused a diagnostic dose of pyridostigmine to see whether it reduces my muscle weakness. Prednisolone really helps, but I'm not allowed it any more, because four courses didn't cure my "mystery" illness!

Why can't I get a trial of pyridostigmine?! From what I read, it's used routinely for diagnosis in the USA, so why not here?

I responded really well to the myasthenia drug pyridostigmine. Which I am still on. After 2 years I asked my local neuro if I could see a myasthenia specialist as I was not responding to treatment like I should. I had a recent scan (Feb) at Queens Sq, by the new specialist seeing about ?

Has anyone in the UK been prescribed pyridostigmine (or similar) on the way to a diagnosis, rather than a treatment? I'm awaiting nerve conduction studies, so I'll throw this new clue into the pot.

I suggested trying a low dose of pyridostigmine, in the hope it revealed a clue one way or the other, but was refused. I've lived with atopic dermatitis and multiple allergies all my life, which are controlled with local steroids, antihistamines and emollients.

I also take the medication Pyridostigmine and I am wondering if this could be having some impact? Any suggestions welcome thanks you.

He’s on steroids and pyridostigmine 3x a day and the double vision is better but that’s the only change. He’s weakness is is extremely bad and we are both getting very discouraged. Has anyone had any experience with myasthenia Gravis. They say the immune therapy has attacked his immune system.

When pressor agents are needed, direct pressor agents (midodrine) or agents that potentiate sympathetic activity (atomoxetine, yohimbine, pyridostigmine) can be used.

I have been taking Methotraxate on the minimum dosage of 3 X 2.5mg once a week and Pyridostigmine at a rate of 2 X 60mg on a daily basis.

Very interested to hear from anyone who is suffering of Ocular Myasthenia and the medication Pyridostigmine. I have had the condition for over a year and have just started Steroids. I am 69 years old married lady with two grown children and three grandchildren.

I also take 75 mg pyridostigmine for myasthenia. Just starting to feel bit numb in mouth/throat , hope that will be temporary and had an episode last week one evening of lightheaded and cool. Weird feeling.

Much easier to do here as neither of us have commitments and our only restrictions are that I can't eat food within 90 mins of taking my Pyridostigmine, sticking to that has meant I no longer need the propathaline to counter the effect of the Pyrid. on bowel and bladder, yeah! One med down!

During the Gulf War, to protect themselves from chemical and biological weapons, Israeli soldiers took a drug called pyridostigmine. Nearly one-quarter of them complained of headaches, nausea, and dizziness – symptoms which occur only if the drug reaches the brain.