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Docetaxel results so far
People want to know if Docetaxel is worth doing due to the side effects. My husband just had a recent PSMA PET scan after 5 treatments and the result is compared with the same scan method done before treatment began: [i]Impression (Summary)[/i] [i]Mild improvement in subcarinal adenopathy, left lung
People want to know if Docetaxel is worth doing due to the side effects. My husband just had a recent PSMA PET scan after 5 treatments and the result is compared with the same scan method done before treatment began: [i]Impression (Summary)[/i] [i]Mild improvement in subcarinal adenopathy, left lung
Tinuriel
in
Advanced Prostate Cancer
5 months ago
PSA went up after three treatments of chemotherapy
I have had 3 Chemotherapy treatments with Docataxel. before the first treatment PSA was 89. after the first treatment PSA was 73.31.. after the second treatment PSA was 52.82. after the third treatment, PSA was 73.31.. does it make sense to take another chemotherapy treatment since the PSA has risen
I have had 3 Chemotherapy treatments with Docataxel. before the first treatment PSA was 89. after the first treatment PSA was 73.31.. after the second treatment PSA was 52.82. after the third treatment, PSA was 73.31.. does it make sense to take another chemotherapy treatment since the PSA has risen
spolyu
in
Advanced Prostate Cancer
5 months ago
Confused about how all the different PCa drugs work?
This recent article (Oct 2023) has a nice high level diagram that organizes the more common prostate cancer drugs and their mechanism of action. Scroll down to Figure 1. De Novo Metastatic Prostate Cancer: Are We Moving toward a Personalized Treatment? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605467
This recent article (Oct 2023) has a nice high level diagram that organizes the more common prostate cancer drugs and their mechanism of action. Scroll down to Figure 1. De Novo Metastatic Prostate Cancer: Are We Moving toward a Personalized Treatment? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10605467
skiingfiend
in
Advanced Prostate Cancer
7 months ago
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Prostate Cancer Highlights from ESMO23
For those interested in the outcomes of recent prostate cancer trials or those just curious about the current thinking on 'where to next' the latest GU Cast podcast from Declan Murphy is well worth watching. The presentation is ‘peppered’ with conversation from the various speakers interviewed that
For those interested in the outcomes of recent prostate cancer trials or those just curious about the current thinking on 'where to next' the latest GU Cast podcast from Declan Murphy is well worth watching. The presentation is ‘peppered’ with conversation from the various speakers interviewed that
marnieg46
in
Fight Prostate Cancer
7 months ago
Radiation?
just got my psa results after my first round of 4 months leuprolide and 3 months Zytiga and prednisone…..initially 18 now 0.04. Nurse told me that my MO would like to see me early to discuss more radiation( recent psma found areas of avidity only in prostate bed……initial tx was 48 grey imrt back in
just got my psa results after my first round of 4 months leuprolide and 3 months Zytiga and prednisone…..initially 18 now 0.04. Nurse told me that my MO would like to see me early to discuss more radiation( recent psma found areas of avidity only in prostate bed……initial tx was 48 grey imrt back in
Tommyj2
in
Advanced Prostate Cancer
5 months ago
Genitourinary Cancers Symposium Meeting Coverage, MedPage Today, January 2024
Latest 2024 PCa-related GuCS Meeting Coverage from MedPage Today: [i]
More Evidence That ARSIs for Prostate Cancer Differ in Cognitive Effects -More fatigue, depression, worse reaction time with enzalutamide as compared with abiraterone, January 29, 2024:
[/i] https://www.medpagetoday.com/meetingcoverage
Latest 2024 PCa-related GuCS Meeting Coverage from MedPage Today: [i]
More Evidence That ARSIs for Prostate Cancer Differ in Cognitive Effects -More fatigue, depression, worse reaction time with enzalutamide as compared with abiraterone, January 29, 2024:
[/i] https://www.medpagetoday.com/meetingcoverage
cujoe
in
Fight Prostate Cancer
5 months ago
Seeking Hope or Similar Stories
Hello! I just joined this community yesterday. My husband has been diagnosed with Gleason 8 prostate cancer with cribriform. PSA 18. His clinical dx is T1c. He had 6 out of12 positive biopsies. All were 4+4. 5 were 40% and 1 was 60%. He has the PSMA test on Monday. The doctor doesn’t think it has
Hello! I just joined this community yesterday. My husband has been diagnosed with Gleason 8 prostate cancer with cribriform. PSA 18. His clinical dx is T1c. He had 6 out of12 positive biopsies. All were 4+4. 5 were 40% and 1 was 60%. He has the PSMA test on Monday. The doctor doesn’t think it has
Darbydood
in
Advanced Prostate Cancer
5 months ago
Post treatment post ADT time to PSMA test
Where I am receiving treatment, ADT, LD Brachytherapy, LINAC radiotherapy (15) sessions.. PSMA pet scans are not available (Japan). I planning on ending adjuvant ADT therapy within a few months and am aware of the lasting effects on testosterone (will take 6-12 months for decent testosterone levels .
Where I am receiving treatment, ADT, LD Brachytherapy, LINAC radiotherapy (15) sessions.. PSMA pet scans are not available (Japan). I planning on ending adjuvant ADT therapy within a few months and am aware of the lasting effects on testosterone (will take 6-12 months for decent testosterone levels .
Yokohama2023
in
Advanced Prostate Cancer
5 months ago
Prostate-as-"PCa Factory" - Reasons for Removal?
While reading the bio of forum member, I noted the following advantage to radical prostatectomy (paraphrased):"
No more PCa factory
" As I have written in multiple posts I am enjoying very effective
triplet therapy
against my high volume metastatic prostate cancer. And because my cancer was
While reading the bio of forum member, I noted the following advantage to radical prostatectomy (paraphrased):"
No more PCa factory
" As I have written in multiple posts I am enjoying very effective
triplet therapy
against my high volume metastatic prostate cancer. And because my cancer was
JohnInTheMiddle
in
Advanced Prostate Cancer
5 months ago
Any experience with Intraductal Cancer?
Not sure how this works. Hopefully you can read my profile to see where I'm at. If not, I repeat it here. My GP recommended biopsy after several annual PSA results around 4.0 Was on active surveillance since diagnosis in 2019 with biopsy Gleason 6 in two cores. Similar result in annual biopsies
Not sure how this works. Hopefully you can read my profile to see where I'm at. If not, I repeat it here. My GP recommended biopsy after several annual PSA results around 4.0 Was on active surveillance since diagnosis in 2019 with biopsy Gleason 6 in two cores. Similar result in annual biopsies
SherpaT
in
Prostate Cancer Network
5 months ago
Unsure of best option in early prostate cancer diagnosis.
I have had PSA tests annually for 10 years and in Oct 2023 had an elevated 6.42 result. Was referred to a urologist, whom performed a DRE. There was prostate enlargement but no tumor discovered through DRE. After discussing several options, I decided to have a biopsy on Nov 21, 2023. Dec 5, 2023,
I have had PSA tests annually for 10 years and in Oct 2023 had an elevated 6.42 result. Was referred to a urologist, whom performed a DRE. There was prostate enlargement but no tumor discovered through DRE. After discussing several options, I decided to have a biopsy on Nov 21, 2023. Dec 5, 2023,
cobrasc429
in
Advanced Prostate Cancer
5 months ago
Darolutamide failing after 2 years. Any success if I switch to Xandi or Zytiga or do I need to move to Pluvicto.
Dx 2018. PSA 16. Been on Orgovyx. Started Second line (Darolutamide) two years ago when PSA started to rise. PSA rose over the [u]last 5 months[/u] from 0.021 (August) to 0.48 I had a few bone mets and several lymph nodes when dx. Trying to find other treatments since I'm running out of Standard
Dx 2018. PSA 16. Been on Orgovyx. Started Second line (Darolutamide) two years ago when PSA started to rise. PSA rose over the [u]last 5 months[/u] from 0.021 (August) to 0.48 I had a few bone mets and several lymph nodes when dx. Trying to find other treatments since I'm running out of Standard
Longterm101
in
Advanced Prostate Cancer
6 months ago
Provenge (only) - impact on overall survival
I just got insurance approval for Provenge...out of pocket is really high so now I'm doing a cost benefit analysis in my mind. I've seen many different articles showing that Provenge ALONE only extends overall survival by 4-15 months. Does that sound correct? Tall_Allen mentioned adding xofigio for
I just got insurance approval for Provenge...out of pocket is really high so now I'm doing a cost benefit analysis in my mind. I've seen many different articles showing that Provenge ALONE only extends overall survival by 4-15 months. Does that sound correct? Tall_Allen mentioned adding xofigio for
Gl448
in
Advanced Prostate Cancer
5 months ago
Overall Survival With [177]Lu-PSMA-617 vs Cabazitaxel in Metastatic Castration-Resistant Prostate Cancer
The Lancet Oncology TAKE-HOME MESSAGE TheraP was a phase II trial that compared the efficacy of radioligand therapy with 177Lu-PSMA-617 with that of cabazitaxel in patients with metastatic castration-resistant prostate cancer who had previously received docetaxel. After a median follow-up of 35.7 months
The Lancet Oncology TAKE-HOME MESSAGE TheraP was a phase II trial that compared the efficacy of radioligand therapy with 177Lu-PSMA-617 with that of cabazitaxel in patients with metastatic castration-resistant prostate cancer who had previously received docetaxel. After a median follow-up of 35.7 months
Magnus1964
in
Advanced Prostate Cancer
6 months ago
Criteria for "my ADT has stopped working and we have to move to another"
Hello - So my third post ADT initiation (Lupron+Abi) PSA test is coming up and since it was <.1 six weeks ago, I asked how the criteria of “has stopped working” works -to my Hopkins MO and I got this - “We want to declare a therapy no longer effective when PSA is clearly going up. We look for 0.3
Hello - So my third post ADT initiation (Lupron+Abi) PSA test is coming up and since it was <.1 six weeks ago, I asked how the criteria of “has stopped working” works -to my Hopkins MO and I got this - “We want to declare a therapy no longer effective when PSA is clearly going up. We look for 0.3
jackwfrench
in
Advanced Prostate Cancer
6 months ago
To Chemo or Not to Chemo--that is the ?
Should I follow my MO's advice and do docetaxel? Since I'm now 78, and have read terrible accounts of chemo, I have held onto the belief that I would do everything to avoid chemo since the treatment appears to be worse than the alternative. But she's really not giving me an alternative, other than
Should I follow my MO's advice and do docetaxel? Since I'm now 78, and have read terrible accounts of chemo, I have held onto the belief that I would do everything to avoid chemo since the treatment appears to be worse than the alternative. But she's really not giving me an alternative, other than
LifeQuality
in
Advanced Prostate Cancer
5 months ago
Mark Buckley
Problem start in May 2023. Diagnosed with prostate cancer in August 2023. Started Bicalutamide 30th August 2023. 1 tablet x daily. Ended 19th September 2023. Started Contiflo XL 24th August 2023. 1 x daily. Ended 22nd September 2023. Hormone Implant called Zoladex LA 10.8mg 6th September 2023,
Problem start in May 2023. Diagnosed with prostate cancer in August 2023. Started Bicalutamide 30th August 2023. 1 tablet x daily. Ended 19th September 2023. Started Contiflo XL 24th August 2023. 1 x daily. Ended 22nd September 2023. Hormone Implant called Zoladex LA 10.8mg 6th September 2023,
whatisontheriver
in
Advanced Prostate Cancer
7 months ago
BCF after 9 years post proton therapy
My PSA had been increasing slowly since my nadir of .75 in 2017 reaching 1.19 in 2022. Both RO and Uro weren't terribly concerned. I wanted PSMA after 3rd consecutive increase but both recommended a wait and see approach, especially the RO who seems honor bound to wait for 2.0 over nadir. I skipped
My PSA had been increasing slowly since my nadir of .75 in 2017 reaching 1.19 in 2022. Both RO and Uro weren't terribly concerned. I wanted PSMA after 3rd consecutive increase but both recommended a wait and see approach, especially the RO who seems honor bound to wait for 2.0 over nadir. I skipped
hwrjr
in
Prostate Cancer Network
5 months ago
HoLEP Affect on Pca
as posted earlier, I have both BPH (80 cc) and localized prostate cancer. Clear PSMA. I’m having HoLEP surgery. Wonder how this will impact the cancer. How will PSA respond? What happens if HoLEP actually removed the cancer?
as posted earlier, I have both BPH (80 cc) and localized prostate cancer. Clear PSMA. I’m having HoLEP surgery. Wonder how this will impact the cancer. How will PSA respond? What happens if HoLEP actually removed the cancer?
Bourbon2024
in
Prostate Cancer Network
5 months ago
Helpful group
Hello All, This group has been very helpful in providing information and suggestions on PC. I was diagnosed in Sept. 23 as Stage 4, Gleason 7 with all core samples testing positive and one met to the sacrum. Just completed 28 rounds of IMRT and have been on Lupron, Xtandi and Zometa for the last two
Hello All, This group has been very helpful in providing information and suggestions on PC. I was diagnosed in Sept. 23 as Stage 4, Gleason 7 with all core samples testing positive and one met to the sacrum. Just completed 28 rounds of IMRT and have been on Lupron, Xtandi and Zometa for the last two
Jeffdanger
in
Advanced Prostate Cancer
5 months ago
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