Experiences with

Palbociclib

In time of palbociclib treatment. Also if its there what will be the next treatment? Again chemo is required?

So same medicines prescribed, but now suddenly in both legs nerves are paining like shooting pain heavily, will palbociclib or letrozole affect nerves if taken for 6 months?

"The drug, palbociclib, may be able to prevent the scarring of bone marrow that existing treatments (Rux etc) for myelofibrosis cannot."

which is more effective palbociclib or ribociclib? My onc said ribociclib is and recommended to continue with it. have you talked to the doctors about it?But it is 2 times more expensive and I am self-financed. I can't afford it financially Palbo is works well for the fourth year.

Itovebi (inavolisib) in combination with palbociclib and fulvestrant as a new treatment for advanced breast cancer: We all need some good news!.

I'm still on 125 of palbociclib. I'm as fit as I could have expected at 75 and work most days in the garden, walk the dog and generally dash about. We've been Bonar bridge for over a year.

for those on palbociclib, when asked if you’re on chemotherapy and you can only give a yes /no answer do you say yes as palbo is a targeted chemo?

I've been on a regimen of Palbociclib and Letrozole for the past 19 days, and recently, I received my CA153 test results. Last month, before starting the Palbociclib and Letrozole treatment, my CA153 level was recorded at 137.

Haven’t had any palbociclib since December due to covid reaction/ ops and it was originally grade 3 pleomorphic. I have no desire to repeat this traumatising experience despite excellent care - way too many needles and cannulas for one.

I've not had palbociclib for several weeks already because of a post-covid cold which the surgeons aren't too bothered about but it means I won't be having palbo for several more weeks until healed and I'm 2.3 yrs into palbo/letrozole treatment .

Copied from under "Abstract" paragraph: Palbociclib, 5-days-on/2-days-off weekly, met its primary endpoint with reduced G3 + ANC, without compromising efficacy. sTK1 is prognostic and shows promise in monitoring the palbociclib response. ClinicalTrials.gov#: NCT3007979. Here's the whole article.

There’s one full pack of Palbociclib/Ibrance. 100mg. And there’s also a packet of anastrozole. Please refer to the photo I’ve put here. If anyone to use these I’m very happy to post them to you anywhere in the world.

I had a mastectomy and axillary clearance left side and then palbociclib, letrezole, monthly goserelin and denusamab. I have just found out I have my first progression spine and possible lesion on my liver but more concerning a new primary lobular carcinoma in my right breast and armpit lymph.

I’ve also restarted cancer meds (palbociclib and denosumab) in addition to letrazole and calcium taken continuously. However I’ve suddenly put on 6lb weight in past week and my nails keep breaking.

Currently: 7am T4/T3 with oral asthma spray 9.30am Breakfast with palbociclib, letrozole and oral spray Vit D/K2 3pm T3 (5mcg)* 6pm Glucosamine/chondroitin 10pm Calcium *I struggle to remember the afternoon T3 dose as despite phone alerts,

Interested in any comments about Faslodex, although I had none of the suggested bad side effects for letrozole or palbociclib.

If you are taking it, had you previously used Ibrance until it failed? I'm on Piqray and faslodex right now but feeling like the end of this run is near so Im wondering g if there is anyone who has successfully returned to Ibrance with the addition of itovebi (inavolisib) and faslodex? Such a grab

I am stable and still on my 1st line of treatment which is Palbociclib 75mg, letrozole, denosumab and zoladex. Because of low neutrophils I am on a 6 wk cycle, 3weeks on 3 weeks off, with the denosumab being 6 weekly inline with the other treatment which I administer myself.

Leterzol and palbociclib was no longer working. In the summer I moved to Fasolodex and a second trial drug. I felt okay, but some stomach side effects. In August I discovered it had failed me completely and my growths had doubled. I then caught covid and finally mid September started capcitamone.

These data support first-line palbociclib plus an AI treatment for HR+/HER2− MBC.