painful fingers and nails on Piqray

[Dragonfly2]

I’ve done a search on our blog but didn’t find anything specific…It’s been about 8 months on Piqray, and after an array of all the early side effects, I’m now dealing with painful finger tips and nails. I can deal with the thinning hair and fatigue but it makes me so sad to give up a lot of my hand dexterity. I think it’s the hand and foo5 syndrome that is associated with Piqray…but no blistering or redness 🙏🙏🙏🙏 but my nails are peeling back to the nail bed and I have painful fingertips. I’m taking 900 mg daily of gabapentin but I’m wondering if it’s working 🙄. I

Is anyone dealing with similar issues and have yiu found any relief beyond gloves and hand creams ? Best wishes to you all…and fingers crossed on the introduction of a new drug. Itovebi (inavolisib) in combination with palbociclib and fulvestrant as a new treatment for advanced breast cancer:

We all need some good news!.

[13plus]

Sorry to hear you have that side effect. Is there any chance of lowering the dose? If it is hfs I had that while on Xeloda. Mostly my feet but one particular cycle it was all about my finger tips being sore like you describe. I couldn’t open plastic food containers with the thin edges! It was crazy really. Lowering the dose helped immensely, so perhaps ask about that. We do need to find that QOL balance!

[Dragonfly2 in reply to 13plus]

thank you… I just did go on a lower dose to 250. Maybe this will subside in a little while! (Painful) fingers crossed! ❤️‍🩹❤️‍🩹