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New Opiod Registry Paper published! Year 4.
Results At 4-years, 423 participants continue opioid treatment and study participation (5.8% lost to follow-up or withdrew, 2.4% died, 6.6% stopped
opioids
). Methadone and oxycodone are the two most common
opioids
(taken by 54.7% and 21.9% of 4-year participants, respectively).
Results At 4-years, 423 participants continue opioid treatment and study participation (5.8% lost to follow-up or withdrew, 2.4% died, 6.6% stopped
opioids
). Methadone and oxycodone are the two most common
opioids
(taken by 54.7% and 21.9% of 4-year participants, respectively).
RLSLearner
in
Restless Legs Syndrome
5 months ago
pregabalin vs buprenorphine
When I started, I assumed I would want to come off the buprenorphine and replace it with pregabalin, mainly because of my doctor’s unease with
opioids
. But now I’m wondering what choice other sufferers would make? The buprenorphine (Suboxone) seems to be working well (2mg/.5mg strips).
When I started, I assumed I would want to come off the buprenorphine and replace it with pregabalin, mainly because of my doctor’s unease with
opioids
. But now I’m wondering what choice other sufferers would make? The buprenorphine (Suboxone) seems to be working well (2mg/.5mg strips).
707twitcher
in
Restless Legs Syndrome
9 months ago
What should I expect at the end?
He was mobile up until a week ago and that’s when his pain became uncontrollable, although he was not taking his
opioids
(he was many months without them - not needing them) and was being stubborn.
He was mobile up until a week ago and that’s when his pain became uncontrollable, although he was not taking his
opioids
(he was many months without them - not needing them) and was being stubborn.
Pechey
in
Advanced Prostate Cancer
8 months ago
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Fed up with the BS doctors give you
They say more
opioids
will only make the headaches worse.
They say more
opioids
will only make the headaches worse.
terry9griffins
in
Functional Neurological Disorder - FND Hope
8 months ago
why docs don’t want to prescribe opioids for RLS….😔
With all the recent total panic by docs on not prescribing
opioids
, I thought I would just attach Andy Berkowski’s excellent piece on why we are often being refused
opioids
now and almost certainly in the future at least for sometime.
With all the recent total panic by docs on not prescribing
opioids
, I thought I would just attach Andy Berkowski’s excellent piece on why we are often being refused
opioids
now and almost certainly in the future at least for sometime.
Kakally
in
Restless Legs Syndrome
1 year ago
Bilateral Neuropathy in my legs and arms. I have a Nevro implant that stopped functioning. Now I require opioids to managing my pain.
My only option today is
opioids
to control my pain. My pain is all-encompassing where I can only reduce the condition. The non-VA medical profession will chastise me at every opportunity. Clearly, they have never been in pain that is relentless.
My only option today is
opioids
to control my pain. My pain is all-encompassing where I can only reduce the condition. The non-VA medical profession will chastise me at every opportunity. Clearly, they have never been in pain that is relentless.
Hidden
in
Pain Concern
11 months ago
Opioids can cause adrenal insufficiency
Hi everyone, It appears that
opioids
can cause adrenal insufficiency. This is something I have not seen mentioned here. Does anyone know about this? Here are a few articles.
Hi everyone, It appears that
opioids
can cause adrenal insufficiency. This is something I have not seen mentioned here. Does anyone know about this? Here are a few articles.
sferios
in
PMRGCAuk
1 year ago
Medscape article on RLS
We should no longer offer
opioids
for the treatment of RLS. There's been a real shift away from the use of dopamine agonists over the years due to augmentation of symptoms, loss of efficacy, and the risk of impulse control disorders.
We should no longer offer
opioids
for the treatment of RLS. There's been a real shift away from the use of dopamine agonists over the years due to augmentation of symptoms, loss of efficacy, and the risk of impulse control disorders.
thorp
in
Restless Legs Syndrome
5 months ago
Urgently seeking pain management tips
I know there’s plenty of women here who have pain so I am curious if there are other alternatives that are not
opioids
that have worked successfully for you? (Oh, and my liver mets have increased so I think the codeine things are not good for that.) Probably this week I will start on Xeloda :(
I know there’s plenty of women here who have pain so I am curious if there are other alternatives that are not
opioids
that have worked successfully for you? (Oh, and my liver mets have increased so I think the codeine things are not good for that.) Probably this week I will start on Xeloda :(
13plus
in
SHARE Metastatic Breast Cancer
9 months ago
Alternating cannabis and pramipexole
They're following the Mayo algorithm so I have to do this before they'll consider
opioids
. I've tried pregabalin, etc without success. Starting pramipexole on .125mg, up to max .75mg. I'm too scared to take them due to potential augmentation and the horror stories.
They're following the Mayo algorithm so I have to do this before they'll consider
opioids
. I've tried pregabalin, etc without success. Starting pramipexole on .125mg, up to max .75mg. I'm too scared to take them due to potential augmentation and the horror stories.
Rayme
in
Restless Legs Syndrome
10 months ago
neuropathic pain from paralysed arm (trauma)
Having been to a pain clinic in England which consistent of not medical staff introducing information about
opioids
use, mindfulness and pacing. A lot I had already learned myself so this wasn’t really useful to me.
Having been to a pain clinic in England which consistent of not medical staff introducing information about
opioids
use, mindfulness and pacing. A lot I had already learned myself so this wasn’t really useful to me.
Hidden
in
Pain Concern
8 months ago
Amitriptyline and cortisol
I have found many peer-reviewed articles claiming the same thing about
opioids
and benzodiazpines also, but it seems to be more pronounced for amitriptyline.
I have found many peer-reviewed articles claiming the same thing about
opioids
and benzodiazpines also, but it seems to be more pronounced for amitriptyline.
sferios
in
PMRGCAuk
1 year ago
Severe muscle pain after walking
For months I took prescription
opioids
and baclofen at the full dose I was allowed, 24/7. My pain doctor said I needed a baclofen pump for that and tight muscles in my neck area.
For months I took prescription
opioids
and baclofen at the full dose I was allowed, 24/7. My pain doctor said I needed a baclofen pump for that and tight muscles in my neck area.
CatsandCars
in
My MSAA Community
10 months ago
Use of opioids for Ropinirole withdrawal
I am starting to reduce the amount of Ropinirole I take by small amounts. I note that a low dose opioid can help with the withdrawal symptoms. My withdrawal RLS symptoms start during the morning and I'm trying not to take any ropinirole until the evening, in order to help my sleep. Will taking a low
I am starting to reduce the amount of Ropinirole I take by small amounts. I note that a low dose opioid can help with the withdrawal symptoms. My withdrawal RLS symptoms start during the morning and I'm trying not to take any ropinirole until the evening, in order to help my sleep. Will taking a low
Seakale
in
Restless Legs Syndrome
1 month ago
Reintroducing DA at a low dose?
Another option is codeine however as with other
opioids
i experience marked insomnia on it (even while taking 300mg pregabalin). Buprenorphine is a third option but i'm not sure i can deal with the accompanying nausea (that i experienced previously) right at this point in time.
Another option is codeine however as with other
opioids
i experience marked insomnia on it (even while taking 300mg pregabalin). Buprenorphine is a third option but i'm not sure i can deal with the accompanying nausea (that i experienced previously) right at this point in time.
Hidden
in
Restless Legs Syndrome
1 year ago
Oxycodon
He said I would probably need stronger
Opioids
. I tried to resist these as long as possible. I had COVID a second time in September ( not too bad ) and then just kept ill . Would get over one thing and then be ill again . No energy , very breathless.
He said I would probably need stronger
Opioids
. I tried to resist these as long as possible. I had COVID a second time in September ( not too bad ) and then just kept ill . Would get over one thing and then be ill again . No energy , very breathless.
mantel
in
Restless Legs Syndrome
8 months ago
Low dose opioids
Hi, Does anyone know a doctor in the UK South East who I can see privately who will prescribe low dose
opioids
? I'm on 1800mg gabapentin and still having very bad symptoms. Thank you!
Hi, Does anyone know a doctor in the UK South East who I can see privately who will prescribe low dose
opioids
? I'm on 1800mg gabapentin and still having very bad symptoms. Thank you!
Believer1234
in
Restless Legs Syndrome
1 year ago
The problem with Buprenorphine, BTBD9 and serotonin syndrome
For instance,
opioids
stimulate mast cells, and this increases histamine release. Quetiapine is, amongst other things, antihistaminic and anticholinergic.
For instance,
opioids
stimulate mast cells, and this increases histamine release. Quetiapine is, amongst other things, antihistaminic and anticholinergic.
Typicallygaslit
in
Restless Legs Syndrome
9 months ago
opioid not working at all
I’m disappointed as I’ve read lots of positive results of people using
opioids
. Thank you.
I’m disappointed as I’ve read lots of positive results of people using
opioids
. Thank you.
Allatonce
in
Restless Legs Syndrome
1 year ago
Buprenorphine is not that harmless
dear (some) forum members, please stop recommending buprenorphine as if it were nothing. a serious side effect can be (if not even: will be) neuroinflammation (microglia-mediated inflammatory response) because it blocks the kappa opioid receptor, unlike other
opioids
. this is serious.
dear (some) forum members, please stop recommending buprenorphine as if it were nothing. a serious side effect can be (if not even: will be) neuroinflammation (microglia-mediated inflammatory response) because it blocks the kappa opioid receptor, unlike other
opioids
. this is serious.
snoemata
in
Restless Legs Syndrome
1 year ago
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