Experiences with

Omalizumab

Hi, has anyone tried the above injections. I have been approved for this as I have allergic asthma and EILO. I'm currently permanently on Prednisone as inhalers do not work for me and hoping with these injections to be able at some point come off Prednisone. Any feedback would be greatly appreciated

Hi all, Is there anyone who tried omalizumab as a way to manage pruritus? It looks like was quite successful in a small study. https://www.google.ro/url?

Mepo, Benra and Omalizumab didn't work well enough to get me off steroids.I reckon I have had 60+ courses of steroids in the last eight years. My condition has robbed me of the ability to do what I used to do - hobbies are a distant memory. I work and sleep.

Unfortunately despite having mepolizumab, benralizumab and omalizumab I have had little relief - eosinophils and FeNo remain high. To have a normal (ish) life I need 50 mg of steroids a day - out of the question. After finishing on omalizumab I was uncertain what the hospital could do.

He has severe allergic and Eosinophilic asthma but his IGE is to high for Omalizumab to be used as his first biologic and as he is under 18 Mepo is therefore the only option at this stage.

Attended the hospital today - was given possibly my final shot of benra after being told I would be switched to omalizumab. The consultant explained that even after being given biologics and taking large doses of steroids my eosiniphils remain very high.

As a side note: Finally got a start date for Omalizumab with my allergist at the end of September, so hoping it helps my asthma out too!

Over the months I’ve been on all sorts of medication and now under hospital and have started omalizumab and had 2nd set of injections and continue to take 4 antihistamine daily. Although I remain optimistic I continue to suffer with the urticaria and extreme itch.

Been struggling too long, I am finally due the omalizumab injection next week so I am hoping this helps now matter what condition I may have. Thank you ☺️

The main injections for asthma are: benralizumab (Fasenra) omalizumab (Xolair) mepolizumab (Nucala) reslizumab (Cinqaero) These medicines are not suitable for everyone with asthma and can only be prescribed by an asthma specialist.

I’ve been diagnosed with serve allergic asthma on Omalizumab, Fostair 200/6 2bd & qvar 100 4 puffs twice a day, ventolin as required. On montelukast, carbocestine, fexodenadine, various nasal drops. Had a flare up two weeks ago & had to attend a&E twice despite having 40 mg prednisone for 5 days.

Still on Omalizumab, fostair, qvar, fexodenadine, montelukast, ventolin, antihistamine nasal spray, Carboceistibe (sp), nasal wash out etc. and still having regular flare ups since January. Why doesn’t anything seem to work!!

OMALIZUMAB/XOLAIR Xolair blocks the action of IgE which then hopefully causes less allergic reactions.

Although it doesn't itch as much as it used to , i still have it .Omalizumab is not totally working ; l take also cetirizine ( 20mg per day ) Is there anything else l could try apart from prednisolone ?

If any anyone knows if new Omalizumab Bio-similars are yet licensed for use in the UK, it would be good to here from you, with the drug’s brand name.

If you are, or your child is, taking: Any biologic therapy, also called a mAb (Xolair/omalizumab, Nucala/mepolizumab, Cinqaero/reslizumab, Fasenra/benralizumab) Steroid tablets or liquid every day Antibiotic tablets or liquid for asthma every week (e.g. azithromycin) Tiotropium A combination inhaler

Just wanted to do a quick poll for those of you on xolair (omalizumab)—how long did it take to kick in and start controlling your symptoms? I’m getting my sixth shot in a week but am still struggling. Thanks!!

After discussing it at the appointment on Thursday we decided to retest my blood to see if my IGE has fallen below 700 ( as currently at 780) if it has then I can start the Omalizumab. If it’s gone above 800 we’ll go with the Kenalog to bring it down and then move to Omalizumab.

We finally had a plan, go to nhs England for Omalizumab if funding not granted go with Kenalog (steroid injection). Now I’ve been told, to get Omalizumab I need to lose 9kg before putting in an application for the funding. Or go straight to trying Kenalog. I don’t know what to do!

He discussed desensitisation therapy and also the possibility of initiating Omalizumab treatment- this is where it gets frustrating. Unfortunately, I don't currently qualify for the treatment because I have not been prescribed enough courses of steroids in the last year....arghhhh!