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No benefit of chemo for ER+HER2- invasive lobular beyond estrogen therapy
Just found this in the digest I get of medical journal articles (MD Edge): Women with estrogen receptor (ER)–positive, human epidermal growth factor receptor 2 (HER2)–negative invasive lobular carcinoma who are treated with endocrine therapy do not derive any additional survival benefit from neoadjuvant
Just found this in the digest I get of medical journal articles (MD Edge): Women with estrogen receptor (ER)–positive, human epidermal growth factor receptor 2 (HER2)–negative invasive lobular carcinoma who are treated with endocrine therapy do not derive any additional survival benefit from neoadjuvant
TammyCross
in
SHARE Metastatic Breast Cancer
6 months ago
Update on B1 dose increase after 4+ years
This was my original post on this topic: https://healthunlocked.com/cure-parkinsons/posts/149634530/increasing-my-dose-of-b1-after-4-years-and-7-months That was from June of 2023. I continued at the higher dose (2 grams/day) until the middle of August, then I started having symptom recurrence (brain
This was my original post on this topic: https://healthunlocked.com/cure-parkinsons/posts/149634530/increasing-my-dose-of-b1-after-4-years-and-7-months That was from June of 2023. I continued at the higher dose (2 grams/day) until the middle of August, then I started having symptom recurrence (brain
1LittleWillow
in
Cure Parkinson's
6 months ago
PSA suppression
My PSA lows tend to be around 3.3, and it occurs to me that some might think it odd that I don't drive it lower. I think it is very common for men on ADT to draw too much comfort from a significant PSA reduction, if not a near-zero PSA. I have witnessed men misinterpret a dramatic drop in PSA as
My PSA lows tend to be around 3.3, and it occurs to me that some might think it odd that I don't drive it lower. I think it is very common for men on ADT to draw too much comfort from a significant PSA reduction, if not a near-zero PSA. I have witnessed men misinterpret a dramatic drop in PSA as
pca2004
in
Fight Prostate Cancer
6 months ago
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Sudden change in fT4 levels
I just want to stop sweating (not menopause - already taking max dose of
oestrogen
for premature onset of that) and for my hands to stop hurting. But I don't want to achieve this at the cost of having to live with hypo symptoms. If you've made it this far, thank you. Any advice?
I just want to stop sweating (not menopause - already taking max dose of
oestrogen
for premature onset of that) and for my hands to stop hurting. But I don't want to achieve this at the cost of having to live with hypo symptoms. If you've made it this far, thank you. Any advice?
hose1975
in
Thyroid UK
11 months ago
frozen cycle medication questions
hi everyone , I’m only on my second day of estrogen tablets 3x a day and I feel so sick , did anyone have this and did your dose need amending ? My clinic haven’t done any blood tests on me to check my levels pre cycle or during my previous fresh back in November. I know sometimes hormone levels going
hi everyone , I’m only on my second day of estrogen tablets 3x a day and I feel so sick , did anyone have this and did your dose need amending ? My clinic haven’t done any blood tests on me to check my levels pre cycle or during my previous fresh back in November. I know sometimes hormone levels going
Natasha2012
in
Fertility Network UK
7 months ago
Perimenopausal questions
Hello, over the summer I tested my hormones during my luteal phase. I also have an underactive thyroid too which I know can cause low progesterone. A bit about my symptoms: I have low moods, tiredness, vaginal dryness, no libido, a three week cycle, heavy periods. My GP has prescribed me a estrogen based
Hello, over the summer I tested my hormones during my luteal phase. I also have an underactive thyroid too which I know can cause low progesterone. A bit about my symptoms: I have low moods, tiredness, vaginal dryness, no libido, a three week cycle, heavy periods. My GP has prescribed me a estrogen based
Auntbessy
in
Menopause and Perimenopause Support
7 months ago
Anyone know anything about TRH ?
Estrogen dominance and TRH is there a doctor that helps with this on NHS
Estrogen dominance and TRH is there a doctor that helps with this on NHS
Stace268
in
Thyroid UK
7 months ago
After help for a friend, only able to do natural transfers due to migraine?
You all helped me so much when I was on my fertility journey I was hoping you had some information to help my friend.When she was on a contraceptive pill she had to be on progesterone only as she'd previously had a migraine (only 1 or 2 in her lifetime). A couple of months ago she had an EC and transfer
You all helped me so much when I was on my fertility journey I was hoping you had some information to help my friend.When she was on a contraceptive pill she had to be on progesterone only as she'd previously had a migraine (only 1 or 2 in her lifetime). A couple of months ago she had an EC and transfer
Sw1234
in
Fertility Network UK
7 months ago
Help for a newbie at start of journey
Hi there. Just joined the forum and its a fantastic source of information - thank you. Was just diagnosed with hypothyroid a week ago after 4 years of feeling totally wiped out so trying to get to grips with it all and can see from the forum its a bit of a journey to try to get well again. Would appreciate
Hi there. Just joined the forum and its a fantastic source of information - thank you. Was just diagnosed with hypothyroid a week ago after 4 years of feeling totally wiped out so trying to get to grips with it all and can see from the forum its a bit of a journey to try to get well again. Would appreciate
Irish_Gal
in
Thyroid UK
5 months ago
Hashimotos, low TSH, normal t4, Feeling so ill
I have had Hashimotos for 25 years, GP advised that is hypothyroidism, and have been on T4 levothyroxine replacement for 25 years. Before that I was ok for 2 years Before that I had raging Graves hyperthyroidism for 2 years ( they gave me 200% recommend dose of carbimazole my resting heart rate went
I have had Hashimotos for 25 years, GP advised that is hypothyroidism, and have been on T4 levothyroxine replacement for 25 years. Before that I was ok for 2 years Before that I had raging Graves hyperthyroidism for 2 years ( they gave me 200% recommend dose of carbimazole my resting heart rate went
Brn2BWild
in
Thyroid UK
7 months ago
Bone health follow-up they want to start urgently Zoledronate (zoledronic acid)
my DEXA is -3.7 severe osteoporosis and I’m 48 - started low dose Oestrogel . Saw rheumatologist yesterday who was very rude actually and told me to stop googling He said I will do this yearly infusion. Reading horrific side effect. I’m very weak and fragile and will start some training . I am
my DEXA is -3.7 severe osteoporosis and I’m 48 - started low dose Oestrogel . Saw rheumatologist yesterday who was very rude actually and told me to stop googling He said I will do this yearly infusion. Reading horrific side effect. I’m very weak and fragile and will start some training . I am
Chouchou1234
in
Thyroid UK
5 months ago
please help .. DEXA -3.7 - 48 years old and only offered Intravenous Zoledronate
my DEXA is -3.7 severe osteoporosis and I’m 48 - stsrtrd low dose Oestrogel . Saw rheumatologist who was very rude actually and told me to stop googling. He said I will do this yearly infusion. Reading horrific side effect. I’m very weak and fragile and started jumping everyday. will start some
my DEXA is -3.7 severe osteoporosis and I’m 48 - stsrtrd low dose Oestrogel . Saw rheumatologist who was very rude actually and told me to stop googling. He said I will do this yearly infusion. Reading horrific side effect. I’m very weak and fragile and started jumping everyday. will start some
Chouchou1234
in
Bone Health and Osteoporosis UK
5 months ago
Don't want to go back on the pill/more surgeries! Deep infiltrating endo on bowel and uterine polyp removed recently for heavy bleeding.
Hello fellow endo warriors. I have a dilemma. I really don't want to go back on the bcp after being on it for 15 years as it has not been effective for my deep infiltrating endo on my bowel. My ultimate goal is to heal endo at the core using non-hormonal & surgery approach. Not just a bandaid solution
Hello fellow endo warriors. I have a dilemma. I really don't want to go back on the bcp after being on it for 15 years as it has not been effective for my deep infiltrating endo on my bowel. My ultimate goal is to heal endo at the core using non-hormonal & surgery approach. Not just a bandaid solution
jen2023
in
Endometriosis UK
7 months ago
Secondary / Central Hypothyroidism Questions?
I had the appointment with the endocrinologist, who said that if there was an issue with the pituitary gland then other hormones such as
oestrogen
would also be off so I would have issues with menstrual cycles which I don't. Is this correct?
I had the appointment with the endocrinologist, who said that if there was an issue with the pituitary gland then other hormones such as
oestrogen
would also be off so I would have issues with menstrual cycles which I don't. Is this correct?
tnefeh
in
Thyroid UK
4 months ago
Coming off hrt
With having stomach problems I was thinking of coming off HRT but I read alot about how low
oestrogen
affects your heart has anybody come off without problems thankyou
With having stomach problems I was thinking of coming off HRT but I read alot about how low
oestrogen
affects your heart has anybody come off without problems thankyou
Tazwaz
in
Menopause and Perimenopause Support
1 year ago
12 days Post Day 5 Embryo Transfer. Grade 4 ab and 2cc. Negative PT. LOOSING FAITH
It is my first time to write and it is very heart breaking it is our 3rd embryo transfer. I am tubeless because of ectopic pregnancy and hydrosalphinx. Did D and C this year for uterine polyps. Under clexane, prednisone, cricone, duphastone, estrogen pills. Where do I go from here? I am defeated and
It is my first time to write and it is very heart breaking it is our 3rd embryo transfer. I am tubeless because of ectopic pregnancy and hydrosalphinx. Did D and C this year for uterine polyps. Under clexane, prednisone, cricone, duphastone, estrogen pills. Where do I go from here? I am defeated and
have_faith12
in
Fertility Network UK
7 months ago
New results. I'd be grateful for some input!
So, after 3 years of testing every 8 weeks or so, I still don't trust my interpretation. 😂 Latest results on 150mcg T4 and 30mcg T3 are: TSH: 0.01 T4: 18.5 (12 - 22) 65% T3: 5.4 (3.1 - 6.8) 62% Previous results on 125mcg levo and 30mcg T3 were: TSH: 0.01 T4: 17.8 (12 - 22) 58% T3: 5.1 (3.1 - 6.8)
So, after 3 years of testing every 8 weeks or so, I still don't trust my interpretation. 😂 Latest results on 150mcg T4 and 30mcg T3 are: TSH: 0.01 T4: 18.5 (12 - 22) 65% T3: 5.4 (3.1 - 6.8) 62% Previous results on 125mcg levo and 30mcg T3 were: TSH: 0.01 T4: 17.8 (12 - 22) 58% T3: 5.1 (3.1 - 6.8)
WitchingHour2point0
in
Thyroid UK
7 months ago
Treatment and Prevention Strategies for Cognitive Function in PCa
Treatment and Prevention strategies for cognitive function in men being treated for advanced prostate cancer. Mild cognitive impairment (“brain fog” chemo-brain”) is common and widely recognized in those being treated with ADT and androgen signaling drugs, as well as with taxane chemotherapy. I am highlighting
Treatment and Prevention strategies for cognitive function in men being treated for advanced prostate cancer. Mild cognitive impairment (“brain fog” chemo-brain”) is common and widely recognized in those being treated with ADT and androgen signaling drugs, as well as with taxane chemotherapy. I am highlighting
MateoBeach
in
Fight Prostate Cancer
7 months ago
Can HRT stop working?
Hi, I had a total hysterectomy June 22 and have been on everol estrogen 100mg patches since and my menopause symptoms were controlled for the most. However, these past few weeks my symptoms have been creeping back starting with sleeplessness, night sweats, brain fog and now my skin is itchy as anything
Hi, I had a total hysterectomy June 22 and have been on everol estrogen 100mg patches since and my menopause symptoms were controlled for the most. However, these past few weeks my symptoms have been creeping back starting with sleeplessness, night sweats, brain fog and now my skin is itchy as anything
EvieJ70
in
Menopause and Perimenopause Support
7 months ago
HRT patch help
I’ve started
oestrogen
patches but I seem to be getting shooting electric shock pains up the side of my head / neck. Has anybody experienced similar? Many thanks xx
I’ve started
oestrogen
patches but I seem to be getting shooting electric shock pains up the side of my head / neck. Has anybody experienced similar? Many thanks xx
Steadman80
in
Fertility Network UK
1 year ago
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