Experiences with

Obeticholic acid

For the latest update on Obeticholic Acid in Europe click here: https://www.pbcfoundation.org.uk/obeticholic-acid-in-europe/ #PBC #SupportforLife

/obeticholic-acid-in-europe/ All the links are at the bottom of the video.

Prof David Jones is our guest for tomorrows #PBC Q&A joined by the #PBCTeam live from the obeticholic acid protest in Brussels! Click here for the privacy of the room: https://www.pbcfoundation.org.uk/events/qa-pbc/ or watch us on Facebook Live at 2pm UK time.

Prof David Jones talks us through the current situation around the future of obeticholic acid (OCA) in Europe and what this means.

Obeticholic Acid in Europe 29/6/2024 We are issuing this guidance in response to the announcement made by the European Medicines Agency (EMA) on 28th June 2024 about the future of obeticholic acid (OCA or Ocaliva) in Europe.

Read all about it here: https://www.pbcfoundation.org.uk/obeticholic-acid-in-europe/

The major changes from the last guideline to this guidance include information about obeticholic acid (OCA) and the adaptation of the guidance format.

The major changes from the last guidance to this guidance include information about obeticholic acid (OCA).

We are emphasising two things in this letter: 1) That Obeticholic Acid, aka OCA or Ocaliva continues to have a license, even if it is still conditional, as a treatment for PBC.

The only approved second line treatment is the use of Ovaliva ( acid) . Bezafibrates (fenofibrates in the US) have been used as well along with Ocaliva but neither of these drug groups are licensed yet. Right now they are being used in clinical trials.

Has anyone noticed weight gain or not being able to lose weight since taking Ocaliva (Obeticholic Acid) please?

Resist temptation to say you don’t know any other than Ursodoil, obeticholic acid, Fenofibrate and clinical trial Setanix I’m looking for supplemental treatments to practice along with these treatments western medicine has to offer

Hello all I’ve just had my second laparoscopic endometriosis surgery. First was 15 years ago and said mild endometriosis. This one found significant moderate-severe endometriosis in 3 different locations which they’ve removed (unsure if they feel they got it all). I’ve also had a scan showing adenomyosis

I have had PMR for 3yrs and had a couple of flares. Gradually got down to 5mg. Have done some yoga and gentle circuit training. (Due to bone condition)Walking has been no problem. My arms have started to ache have been for the last month and just accepted it. Have now got a chest infection. Should

Why: We know that leriglitazone/MIN-102 is effective at slowing the progression of AMN and greatly reducing the risk of cerebral involvement, but unless I'm missing something, it's not available to me here in the US currently. But its prodrug, pioglitazone, is, and given that leriglitazone is one of

Hi All, I recently started Dienogest 3 days I am Having flu like symptoms, sore throat feverish with cramps and Diarrhoea. My bloating has gone miles down. Currently on 30 days bleeding stopped taking Tranexamic acid as it’s not heavy anymore. My question is did anyone experience these side effects?

Hey Up! Had an MRI and DEXA scan. Found I have 4 vertebra with compression fractures. Diagnosed with Osteoporosis by Dr Stephen Orme at Leeds Spire and Nuffield Hospital. Been told to reduce alcohol to 14 units per week (normal NHS guidelines), increase calcium in my diet, take 1000 IU of Vitamin D

This is my first post, apart from responses to others. I had an accident in 2020 and fractured my left hip which required a full hip replacement. This was my first indication that I had osteoporosis as I had a follow-up Dexa scan. I was put on Alendronic acid and calcium and vitamin D tablets. In January

Hello, after 5 years on Alendronic acid my osteoporosis bone count is now worse -4.1 and so I am due to start Evenity (Romosozumab) once my tooth extraction has healed. I would be pleased to hear from anyone has experience of this medication please.

Hello i think I've posted on here before for the same thing I'm not sure, I have a yearly zoledronic acid infusion had the 2nd one end of August had horrible side effects again but went away, judt these few months later I'm in a lot 9f pain again, upper back, lower back , legs, basically nearly my whole