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When is PARP introduced?
Hi My husband is currently on triple therapy ( Docetaxel chemo , Zoladex every 3 months and nubeqa) he has one more chemo round left next week. He is responding well so far as PSA is declining ( see profile for PSA) . I have seen some men are talking a PARP inhibitor and nubeqa and zoladex ( or ADT
Hi My husband is currently on triple therapy ( Docetaxel chemo , Zoladex every 3 months and nubeqa) he has one more chemo round left next week. He is responding well so far as PSA is declining ( see profile for PSA) . I have seen some men are talking a PARP inhibitor and nubeqa and zoladex ( or ADT
positive-thinking
in
Advanced Prostate Cancer
3 months ago
Why do MO's continue to prescribe Lupron ADT for Castrate-Resistant men?
I've never understood why MO's continue to prescribe Lupron ADT (or equivalent ) for men who are
castrate-resistant (CRPC
). Isn't that the definition of CRPC, namely, that ADT is no longer working for those men? Why continue to prescribe a drug that no longer works and that causes such suffering
I've never understood why MO's continue to prescribe Lupron ADT (or equivalent ) for men who are
castrate-resistant (CRPC
). Isn't that the definition of CRPC, namely, that ADT is no longer working for those men? Why continue to prescribe a drug that no longer works and that causes such suffering
janebob99
in
Advanced Prostate Cancer
3 months ago
Losing my pubic hair
Recently I noticed that the skin on my inner legs in the crotch area under my scrotum turned brown and then started to peel like a sunburn. The exposed skin is a healthly pink hue and no longer brown but I lost my pubic hair from this area. Surprisingly the size and shape on the brown spots was very
Recently I noticed that the skin on my inner legs in the crotch area under my scrotum turned brown and then started to peel like a sunburn. The exposed skin is a healthly pink hue and no longer brown but I lost my pubic hair from this area. Surprisingly the size and shape on the brown spots was very
skiingfiend
in
Advanced Prostate Cancer
3 months ago
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length of zoladex and tobelone- side effects felt?
I have been having zoladex injections since November once a month. They advised HRT in Jan due to me experiencing headaches/hot flushes and brain fog (which at the time was the worst) . Since then the mood changes have been a lot to deal with feeling unhappy and down. My sleep pattern is interrupted
I have been having zoladex injections since November once a month. They advised HRT in Jan due to me experiencing headaches/hot flushes and brain fog (which at the time was the worst) . Since then the mood changes have been a lot to deal with feeling unhappy and down. My sleep pattern is interrupted
Homelove
in
Endometriosis UK
3 months ago
question for those who have stopped Lupron after many years of ADT
I have been on Lupron for 8 years with the short-term exception of a high/T clinical trial,( but even during the trial I stayed on Lupron). Anyway I’m undetectable and decided to stop Lupron. 3 months after not getting my shot my T is now a whopping 37. I am curious to hear from some of you who
I have been on Lupron for 8 years with the short-term exception of a high/T clinical trial,( but even during the trial I stayed on Lupron). Anyway I’m undetectable and decided to stop Lupron. 3 months after not getting my shot my T is now a whopping 37. I am curious to hear from some of you who
Chugach
in
Advanced Prostate Cancer
3 months ago
A cause for concern or?
For the past couple of months i started getting notifications via my Samsung 6 watch that my HR was anything from 44 to 52,for more than 10 minutes, numerous times a day or night . I am taking various medications, Bu trans patch, HRT co-codamol 30/500 Pregabalin tramadol & citalopram 40mg. They are
For the past couple of months i started getting notifications via my Samsung 6 watch that my HR was anything from 44 to 52,for more than 10 minutes, numerous times a day or night . I am taking various medications, Bu trans patch, HRT co-codamol 30/500 Pregabalin tramadol & citalopram 40mg. They are
caz1967
in
British Heart Foundation
3 months ago
European Society for Medical Oncology Congress - ESMO 2023 - Two Significant Lutetium Trials -mCRPC
Those following information coming from the ESMO Congress over the last few weeks will be aware of the many presentations focussed on the use of Lutetium. [i]
PSMAfore Study Unveils Game-Changing Results for Prostate Cancer Treatment
[/i] One such highlight was the results from the PSMAfore
Those following information coming from the ESMO Congress over the last few weeks will be aware of the many presentations focussed on the use of Lutetium. [i]
PSMAfore Study Unveils Game-Changing Results for Prostate Cancer Treatment
[/i] One such highlight was the results from the PSMAfore
marnieg46
in
Fight Prostate Cancer
9 months ago
Covid
Hi all I have a dilemma facing me . As you know , I have had covid in the last few weeks and still getting over it . My sons girlfriend is having a party with about 90 people ! . My son is going to propose, which we couldn't be more happier. She had no idea . I have not said for sure I will go, they
Hi all I have a dilemma facing me . As you know , I have had covid in the last few weeks and still getting over it . My sons girlfriend is having a party with about 90 people ! . My son is going to propose, which we couldn't be more happier. She had no idea . I have not said for sure I will go, they
Stavrou1
in
CLL Support
7 months ago
Stopping meds before operation. 😏
Hi Peeps, I hope this UK sunshine has reached you over the last few days and that you are as well as you can be today. I have been told to stop my meds because I have to have a lumpectomy on 8th May 🙄 I had to stop my Tocilizumab and Sulfasalazine 4 weeks before and my Metoject 2 weeks before. I also
Hi Peeps, I hope this UK sunshine has reached you over the last few days and that you are as well as you can be today. I have been told to stop my meds because I have to have a lumpectomy on 8th May 🙄 I had to stop my Tocilizumab and Sulfasalazine 4 weeks before and my Metoject 2 weeks before. I also
Moomin8
in
NRAS
3 months ago
Letrozole
I saw the oncologist yesterday to discuss radiotherapy and hormone therapy.The plan for radiotherapy is on hold ATM because I have an ongoing issue with a seroma on the breast and underarm. During the meeting she said she would give me a prescription for Letrozole, I told her I wasn't happy to start
I saw the oncologist yesterday to discuss radiotherapy and hormone therapy.The plan for radiotherapy is on hold ATM because I have an ongoing issue with a seroma on the breast and underarm. During the meeting she said she would give me a prescription for Letrozole, I told her I wasn't happy to start
LindaLittleBear
in
My Breast Cancer Community
3 months ago
Treatment
My dears, after RP (Gleason 7, 4+3, infected 3 lymph nodes) and lymphadetectomy, radiation and hormone therapy for 39 months, my oncologist took me off hormone therapy with the recommendation of PSA control every 3 months. The last three PSA readings (every three months) were 0.01 / 0.00 / 0.00, I expect
My dears, after RP (Gleason 7, 4+3, infected 3 lymph nodes) and lymphadetectomy, radiation and hormone therapy for 39 months, my oncologist took me off hormone therapy with the recommendation of PSA control every 3 months. The last three PSA readings (every three months) were 0.01 / 0.00 / 0.00, I expect
adam1967adam
in
Advanced Prostate Cancer
3 months ago
Expectations
I have undergone 45 radiation treatments and am on my last month of Eligard. PSA is undetectable and my T is barely existent. No mets detected on prior pet scans. My Urologist and Oncologist are giving me congrats. I understand this is probably a temporary remission (g 4+3 - stage 2/3) but I wonder
I have undergone 45 radiation treatments and am on my last month of Eligard. PSA is undetectable and my T is barely existent. No mets detected on prior pet scans. My Urologist and Oncologist are giving me congrats. I understand this is probably a temporary remission (g 4+3 - stage 2/3) but I wonder
Eadgbe
in
Advanced Prostate Cancer
3 months ago
How prostate cancer transforms into aggressive NEPC following treatment with anti-androgen therapy.
This could be a game changer as it could stop PCa from progressing. Science is going to save us. The development of effective anti-androgen therapies for prostate cancer is a major scientific advance. However, some men who receive these targeted treatments are more likely to develop a deadly treatment-resistant
This could be a game changer as it could stop PCa from progressing. Science is going to save us. The development of effective anti-androgen therapies for prostate cancer is a major scientific advance. However, some men who receive these targeted treatments are more likely to develop a deadly treatment-resistant
Scout4answers
in
Advanced Prostate Cancer
9 months ago
Timing and reasons for Thyroid blood tests
Recommended by numerous research papers that thyroid testing should be in the morning and [u]before[/u] taking daily levothyroxine TSH has a circadian rhythm and is highest in early morning and lowest in afternoon Links to a few research papers and articles https://www.ncbi.nlm.nih.gov/pmc
Recommended by numerous research papers that thyroid testing should be in the morning and [u]before[/u] taking daily levothyroxine TSH has a circadian rhythm and is highest in early morning and lowest in afternoon Links to a few research papers and articles https://www.ncbi.nlm.nih.gov/pmc
SlowDragon
Administrator
in
Thyroid UK
3 months ago
picantaChicken
Hi I’m new, been following the treads of other people’s issues for some time and realise I too need help to as the Gps don’t give much help or advise. Makes me feel like I’m wasting their time . Still that aside I have just read a thread about HRT and Levothyroxine. I’ve been on Kevo thyroxine for
Hi I’m new, been following the treads of other people’s issues for some time and realise I too need help to as the Gps don’t give much help or advise. Makes me feel like I’m wasting their time . Still that aside I have just read a thread about HRT and Levothyroxine. I’ve been on Kevo thyroxine for
PicantaChicken
in
Thyroid UK
3 months ago
What does it mean?
I'm slightly embarrassed to be asking strangers on the internet, but I'm a little frustrated by the lack of information given by the doctors. My dad (63) just got diagnosed - Gleason score 8 - and after a new scan they've concluded there's two mets - one in the pelvic lymph node and one in the seminal
I'm slightly embarrassed to be asking strangers on the internet, but I'm a little frustrated by the lack of information given by the doctors. My dad (63) just got diagnosed - Gleason score 8 - and after a new scan they've concluded there's two mets - one in the pelvic lymph node and one in the seminal
TerribleAtInternet
in
Advanced Prostate Cancer
3 months ago
Pain post SBRT
I'm 59 w/ aPC (4+5) and 7 mets - all bone mets. Started on ADT (Firmagon and Nubeqa) in October 2023. Completed 6 cycles of docetaxel 4 wks ago. Started SBRT yesterday. My side effects thus far were all expected and I was prepared for them. Last night had severe back pain (8 out of 10) which lasted
I'm 59 w/ aPC (4+5) and 7 mets - all bone mets. Started on ADT (Firmagon and Nubeqa) in October 2023. Completed 6 cycles of docetaxel 4 wks ago. Started SBRT yesterday. My side effects thus far were all expected and I was prepared for them. Last night had severe back pain (8 out of 10) which lasted
Eggdoc
in
Advanced Prostate Cancer
3 months ago
Levo and hrt
hello has anyone experienced problems by taking hrt gel patches with Levo , I’ve been feeling ill for ages now light headed , weak legs tired and very down , just trying to rule things out to feel normal again as I can’t go or do anything without feeling like I’m going to pass out Doctors don’t know
hello has anyone experienced problems by taking hrt gel patches with Levo , I’ve been feeling ill for ages now light headed , weak legs tired and very down , just trying to rule things out to feel normal again as I can’t go or do anything without feeling like I’m going to pass out Doctors don’t know
Prosecco1997
in
Thyroid UK
3 months ago
ADT IS DONE. NEXT?
Lupron and Zytiga will have completed 2 years of each in June. I've read some continue Lupron for 3 years or longer. How do you know how long to take? Monitor testosterone and PSA how often? 2 or 3 months?
Lupron and Zytiga will have completed 2 years of each in June. I've read some continue Lupron for 3 years or longer. How do you know how long to take? Monitor testosterone and PSA how often? 2 or 3 months?
rfgh20
in
Advanced Prostate Cancer
3 months ago
Help boosting thyroid without medication?
Hello all I have posted before as my thyroid function is poor but always comes back in range (my TSH never rises even with low levels) so no chance of medication on the NHS (other than statins for high cholesterol which I refuse). I did some recent tests TSH 1.95 (0.27-4.2) T4 14.6 (12-22) T3
Hello all I have posted before as my thyroid function is poor but always comes back in range (my TSH never rises even with low levels) so no chance of medication on the NHS (other than statins for high cholesterol which I refuse). I did some recent tests TSH 1.95 (0.27-4.2) T4 14.6 (12-22) T3
karlek
in
Thyroid UK
3 months ago
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