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VERU Inc.
In the preclinical toxicology studies, VERU-111, at oral doses that had significant antitumor effects, did not result in
neutropenia
or myelosuppression, common dose limiting side effects of other antitubulins including intravenous taxanes or intravenous vinca alkaloids.
In the preclinical toxicology studies, VERU-111, at oral doses that had significant antitumor effects, did not result in
neutropenia
or myelosuppression, common dose limiting side effects of other antitubulins including intravenous taxanes or intravenous vinca alkaloids.
Magnus1964
in
Advanced Prostate Cancer
5 years ago
Lymphocytosis??? Worry about my little girl
Suspected Pathology Leuko: lymphocytosis,
neutropenia
Suspected Pathology Leuko: lymphocytosis,
neutropenia
Princesa0130
in
CLL Support
5 years ago
Link between neutropenia and hypothyroidism
Hi, I've just been told I have
neutropenia
I.e. low white cell count by my GP. Anyone know if there is a link between that and an underactive thyroid?
Hi, I've just been told I have
neutropenia
I.e. low white cell count by my GP. Anyone know if there is a link between that and an underactive thyroid?
AnneGood
in
Thyroid UK
5 years ago
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Coming out of the shadows
I feel like Ibrance is a lifeline and although I have had
neutropenia
a few times I have had very few side effects. My biggest concern is how long will I be able to stay on this miracle drug and then what happens. I find that the information that my oncologist gives me is a bit vague on the future.
I feel like Ibrance is a lifeline and although I have had
neutropenia
a few times I have had very few side effects. My biggest concern is how long will I be able to stay on this miracle drug and then what happens. I find that the information that my oncologist gives me is a bit vague on the future.
Allthatjazz
in
SHARE Metastatic Breast Cancer
5 years ago
A year into MBC to Bones
I've struggled with
neutropenia
and am now on the lowest strength of Ibrance (75mg). My last blood work again showed mild
neutropenia
. My oncologist says this happens usually after a year on Ibrance. I'm now worried about what will happen if I can't take the Ibrance due to
neutropenia
.
I've struggled with
neutropenia
and am now on the lowest strength of Ibrance (75mg). My last blood work again showed mild
neutropenia
. My oncologist says this happens usually after a year on Ibrance. I'm now worried about what will happen if I can't take the Ibrance due to
neutropenia
.
TnQuilter
in
SHARE Metastatic Breast Cancer
5 years ago
Niraparib - The GALAHAD study (NCT02854436).
It was approved on 27 March 2017 in the US {for ovarian cancer}, and has been approved in Europe on 16 November 2017" "The most common side effects in studies were low blood cell counts, namely thrombocytopenia (in 61% of patients, severe in 29%), anemia (in 50%, severe in 25%) and
neutropenia
(in 30%
It was approved on 27 March 2017 in the US {for ovarian cancer}, and has been approved in Europe on 16 November 2017" "The most common side effects in studies were low blood cell counts, namely thrombocytopenia (in 61% of patients, severe in 29%), anemia (in 50%, severe in 25%) and
neutropenia
(in 30%
pjoshea13
in
Advanced Prostate Cancer
5 years ago
Integrating Novel Targets and Precision Medicine Into Prostate Cancer Care—Part 1: The Non-Androgen–Targetable Pathways in Castration-Resist
Treatment toxicities were common, with 25% of previously taxane-exposed patients developing ≥ grade 3
neutropenia
.[35,36] BIND-014 is a docetaxel-containing PSMA-targeted nanoparticle.
Treatment toxicities were common, with 25% of previously taxane-exposed patients developing ≥ grade 3
neutropenia
.[35,36] BIND-014 is a docetaxel-containing PSMA-targeted nanoparticle.
JLS1
in
Advanced Prostate Cancer
5 years ago
FEC versus TAX. ? Advice?
For some reason I had every side effect on the list from
neutropenia
, 2 admissions to hospital , nausea , relentless diarrhoea , pains in joints , legs etc, mouth ulcers,back ache , loss of appetite and despite the use of the difficult cold cap , about 3/4 of my hair!
For some reason I had every side effect on the list from
neutropenia
, 2 admissions to hospital , nausea , relentless diarrhoea , pains in joints , legs etc, mouth ulcers,back ache , loss of appetite and despite the use of the difficult cold cap , about 3/4 of my hair!
Chick44nzrn
in
My Breast Cancer Community
6 years ago
Docetaxel + Androgen-Deprivation Therapy in Patients With High-Risk PCa & Rising PSA - no mets.
The most common grade 3 or 4 hematologic toxic effects in the ADT plus docetaxel arm were
neutropenia
(60 of 125 patients [48.0%]), febrile
neutropenia
(10 [8.0%]), and thrombocytopenia (4 [3.0%]). There was no significant between-arm difference in overall quality of life.
The most common grade 3 or 4 hematologic toxic effects in the ADT plus docetaxel arm were
neutropenia
(60 of 125 patients [48.0%]), febrile
neutropenia
(10 [8.0%]), and thrombocytopenia (4 [3.0%]). There was no significant between-arm difference in overall quality of life.
pjoshea13
in
Advanced Prostate Cancer
6 years ago
what is the main dental management for Neutropenia patient ?
dental management
Neutropenia
patient
dental management
Neutropenia
patient
jumanah
in
CLL Support
6 years ago
Phase 3 ARCHES trial - Enzalutamide + ADT
Lab Abnormalities: In the two placebo-controlled trials in patients with mCRPC, Grade 1-4
neutropenia
occurred in 15% of XTANDI patients (1% Grade 3-4) and 6% of placebo patients (0.5% Grade 3-4).
Lab Abnormalities: In the two placebo-controlled trials in patients with mCRPC, Grade 1-4
neutropenia
occurred in 15% of XTANDI patients (1% Grade 3-4) and 6% of placebo patients (0.5% Grade 3-4).
pjoshea13
in
Advanced Prostate Cancer
6 years ago
So fed up being undiagnosed! What is going on with me?
However, throughout these 2 years, I have had elevated antibodies (current results: T4 16.9, T3 5.0, TSH 1.82, Anti-thyroid peroxidase 205 & anti-thyroglobulin 364, ref range below 60 in both, elevated liver levels and mild
neutropenia
).Recently, my hair has been falling off a lot.
However, throughout these 2 years, I have had elevated antibodies (current results: T4 16.9, T3 5.0, TSH 1.82, Anti-thyroid peroxidase 205 & anti-thyroglobulin 364, ref range below 60 in both, elevated liver levels and mild
neutropenia
).Recently, my hair has been falling off a lot.
heidie
in
Thyroid UK
6 years ago
Travel while in Nadir
Any recommendations about traveling while in chemo nadir (
neutropenia
)? The obvious is avoid large crowds and those who may be ill.
Any recommendations about traveling while in chemo nadir (
neutropenia
)? The obvious is avoid large crowds and those who may be ill.
Maleko808
in
Advanced Prostate Cancer
6 years ago
Neutropenia with Ibrutinib
Husband becoming neutropenic after 2 years on Ibrutinib. Maybe he will be forced to quit treatment if he can’t take it anymore because of that. Is there any other options?
Husband becoming neutropenic after 2 years on Ibrutinib. Maybe he will be forced to quit treatment if he can’t take it anymore because of that. Is there any other options?
marlapoi
in
CLL Support
6 years ago
Help I’ve a new tumour while on chemo clear cell adenocarcinoma aged 40
My last scan was in August and it was clear They did a scan last week as I’m unable to have my 3rd round as I’ve
neutropenia
and it’s revealed a 3 cm tumour on my diaphragm.
My last scan was in August and it was clear They did a scan last week as I’m unable to have my 3rd round as I’ve
neutropenia
and it’s revealed a 3 cm tumour on my diaphragm.
NIKKibailie
in
My Ovacome
6 years ago
CLL and Crohn's
I have been on Imbruvica for 3 Years and currently take 280 mg per day due to severe bleeding and
Neutropenia
problems. I had thought my Crohn's was dormant or nearly so for about the last 20 years. Due to recent problems my gastro Dr.
I have been on Imbruvica for 3 Years and currently take 280 mg per day due to severe bleeding and
Neutropenia
problems. I had thought my Crohn's was dormant or nearly so for about the last 20 years. Due to recent problems my gastro Dr.
GumboKing
in
CLL Support
6 years ago
Emerging cell cycle inhibitors for treating metastatic castration-resistant prostate cancer.
Incremental toxicities such as
neutropenia
are important in this population. Results from most current clinical trials of cell cycle inhibitors in CRPC are still pending but it is anticipated they will provide important insights into the heterogeneous biology of CRPC.
Incremental toxicities such as
neutropenia
are important in this population. Results from most current clinical trials of cell cycle inhibitors in CRPC are still pending but it is anticipated they will provide important insights into the heterogeneous biology of CRPC.
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Neutropenia on Venetoclax
Neutropenia
on Venetoclax. How long does it last and what r treatment options
Neutropenia
on Venetoclax. How long does it last and what r treatment options
ontheblock
in
CLL Support
6 years ago
25 Somatic Gene Mutations!
Despite the blood clot in his neck, hives, extreme fatigue,
neutropenia
, bone pain, nausea....etc......his PSA came down from 1200 to 20. We are pleased with the results! Genetic testing determined that he did not have any Germline mutations, although many in his family are BRCA2 positive.
Despite the blood clot in his neck, hives, extreme fatigue,
neutropenia
, bone pain, nausea....etc......his PSA came down from 1200 to 20. We are pleased with the results! Genetic testing determined that he did not have any Germline mutations, although many in his family are BRCA2 positive.
Hidden
in
Advanced Prostate Cancer
6 years ago
8 years of anemia despite PA diagnosis and consistent treatment
I have been on this regime for over a month with no relief and no change in the anemia or
neutropenia
. I also now have a low reticulocyte count despite now high results for B12 (>1900), Folate (>18.2) and increasing D levels and the anemia remains normocytic and macrocytic.
I have been on this regime for over a month with no relief and no change in the anemia or
neutropenia
. I also now have a low reticulocyte count despite now high results for B12 (>1900), Folate (>18.2) and increasing D levels and the anemia remains normocytic and macrocytic.
Bandit224
in
Pernicious Anaemia Society
6 years ago
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