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Macrophages, type of immune cell, tied to lupus nephritis in children
M1 macrophages may cause more severe kidney disease in young patients Inflammatory macrophages, a type of immune cell tasked with clearing the body of harmful invaders and dead cells, may be linked to more severe lupus nephritis in children with systemic lupus erythematosus, a small study suggests.
M1 macrophages may cause more severe kidney disease in young patients Inflammatory macrophages, a type of immune cell tasked with clearing the body of harmful invaders and dead cells, may be linked to more severe lupus nephritis in children with systemic lupus erythematosus, a small study suggests.
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
5 months ago
PSA after chemo # 4
Hi My husbands last chemo was # 3 and PSA was 0.14, he just got the results from Chemo # 4 and it was at 0.12. This is the slowest decline if you look in the profile Iisted all his PSA results. Should we be worried that this last one barely moved ? Or is this slower decline good news? Thanks for any
Hi My husbands last chemo was # 3 and PSA was 0.14, he just got the results from Chemo # 4 and it was at 0.12. This is the slowest decline if you look in the profile Iisted all his PSA results. Should we be worried that this last one barely moved ? Or is this slower decline good news? Thanks for any
positive-thinking
in
Advanced Prostate Cancer
6 months ago
How Much Carbidopa Levodopa After 5-10 Years? Any other meds?
I am about to "celebrate" the six year anniversary of my Parkinson's disease diagnosis. I currently take five 25/100 Carbidopa Levodopa tablets per day, usually around 9:00 a.m., noon, 3:00 p.m., 6:00 p.m., and 9:00 p.m. although timing varies slightly from day to day. Lately, I have noticed that I
I am about to "celebrate" the six year anniversary of my Parkinson's disease diagnosis. I currently take five 25/100 Carbidopa Levodopa tablets per day, usually around 9:00 a.m., noon, 3:00 p.m., 6:00 p.m., and 9:00 p.m. although timing varies slightly from day to day. Lately, I have noticed that I
jimcaster
in
Cure Parkinson's
6 months ago
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Addison's disease
Spoke with my GP yesterday regarding the extreme fatigue & rollercoaster of crashing following activity. He is now going to test & look at the possibility of Addison's. How does this mesh with PMR and Pred? I'd welcome any advice or better knowledge. Thanks.
Spoke with my GP yesterday regarding the extreme fatigue & rollercoaster of crashing following activity. He is now going to test & look at the possibility of Addison's. How does this mesh with PMR and Pred? I'd welcome any advice or better knowledge. Thanks.
Naim1
in
PMRGCAuk
2 months ago
Excess Folic Acid and Vitamin B12 Deficiency: Clinical Implications?
This is a very recent paper. Some of the areas covered are well-known. Such as not treating B12 deficiency with folic acid. But, in the more speculative parts, I think it does raise questions over the prescribing of high dose (e.g. 5 milligrams a day) of folic acid in those who are currently low in
This is a very recent paper. Some of the areas covered are well-known. Such as not treating B12 deficiency with folic acid. But, in the more speculative parts, I think it does raise questions over the prescribing of high dose (e.g. 5 milligrams a day) of folic acid in those who are currently low in
helvella
in
Pernicious Anaemia Society
2 months ago
Crohns/IBD
I have undiagnosed Crohns/IBD and continuous flares. I had surgery in 2011 resection of 20cm colon. What treatments are effective?
I have undiagnosed Crohns/IBD and continuous flares. I had surgery in 2011 resection of 20cm colon. What treatments are effective?
Lalande
in
Thyroid UK
6 months ago
Rising PCA - on ADT Holiday
Diagnosed Stage 4 oligometastatic (low volume) PCA in 2021. Gleason 7, 4+3 . Completed RT and 18 months on ADT (Nubeqa) paused the ADT in September after PSA non detectable and a fresh set of scans showed no “evidence of disease”. Continued to do bloodwork quarterly and PSA remained at 0. Until
Diagnosed Stage 4 oligometastatic (low volume) PCA in 2021. Gleason 7, 4+3 . Completed RT and 18 months on ADT (Nubeqa) paused the ADT in September after PSA non detectable and a fresh set of scans showed no “evidence of disease”. Continued to do bloodwork quarterly and PSA remained at 0. Until
Kkash
in
Advanced Prostate Cancer
6 months ago
Telephone Consultation Results of:
So, I have just finished my phone consultation. I had my list of questions which I wasn't able to put over to the Consultant without being accused of being rude. This is how it went before I forget: My symptoms as they appear at the moment do not entitle me to any thing other than a 3 day ECG monitor
So, I have just finished my phone consultation. I had my list of questions which I wasn't able to put over to the Consultant without being accused of being rude. This is how it went before I forget: My symptoms as they appear at the moment do not entitle me to any thing other than a 3 day ECG monitor
CavendishCool
in
LUPUS UK
1 month ago
Confused
UPDATE: April 5, 2024 Yesterday was very disappointing as my husbands PSA increased again by 183 points, last month his PSA was 1546 and now it is 1730. All his other CBC results were good. His Alkaline Phosphatase increased 6 points, last month 127 and now 133 but still in range of 40-150. Questioned
UPDATE: April 5, 2024 Yesterday was very disappointing as my husbands PSA increased again by 183 points, last month his PSA was 1546 and now it is 1730. All his other CBC results were good. His Alkaline Phosphatase increased 6 points, last month 127 and now 133 but still in range of 40-150. Questioned
MsHope
in
Advanced Prostate Cancer
6 months ago
Psa level
Just came off degarlix as psa level was rising, now on xtadi apalutamide how long does it take for psa level to fall and by how much?
Just came off degarlix as psa level was rising, now on xtadi apalutamide how long does it take for psa level to fall and by how much?
littlemount
in
Advanced Prostate Cancer
6 months ago
New diagnosis - what to expect/demand from GP
I had my second child in August 2022 and to be honest I've not felt right since. Since going back to work in June last year I've been permanently exhausted but it's just got worse and worse. Totally mental fog, can't focus, constantly yawning my head off. My body aches constantly but all the while I
I had my second child in August 2022 and to be honest I've not felt right since. Since going back to work in June last year I've been permanently exhausted but it's just got worse and worse. Totally mental fog, can't focus, constantly yawning my head off. My body aches constantly but all the while I
Whatdidyousay
in
Thyroid UK
2 months ago
fibroscan score 7.9 f1 finrosis
I don’t understand this report as 7.9 Kos should indicate f2 fibrosis not f1 also the did not give me a cap score Not overweight very fit active no alcohol or any kind of hepatitis not hereditary conditions either So quite confused
I don’t understand this report as 7.9 Kos should indicate f2 fibrosis not f1 also the did not give me a cap score Not overweight very fit active no alcohol or any kind of hepatitis not hereditary conditions either So quite confused
TacosPizzaIcecream
in
British Liver Trust
6 months ago
My gfr is om 15 % already but I dont want dialysis
Hi everyone happy Easter, hope everyone is well so I'm already at 15 % gfr and so worried I do want to get in dialysis I want to go straight to the transplants . I when to recently get blood work at my gyno and it should my gfr 15 % but I have a cold and was a bit dehydrated since I drank k 2 bottle
Hi everyone happy Easter, hope everyone is well so I'm already at 15 % gfr and so worried I do want to get in dialysis I want to go straight to the transplants . I when to recently get blood work at my gyno and it should my gfr 15 % but I have a cold and was a bit dehydrated since I drank k 2 bottle
jennifer24
in
Early CKD Support
6 months ago
NCT04662580 - All about ARX517 as Monotherapy
Hello, Tomorrow I am going to participate in ARX517 as Monotherapy. Here is the clinical trial: https://www.clinicaltrials.gov/study/NCT04662580. Share your questions / positive comments. I will update here Special request to
Tall_Allen
- Please tell : what should I ask ? [
Hello, Tomorrow I am going to participate in ARX517 as Monotherapy. Here is the clinical trial: https://www.clinicaltrials.gov/study/NCT04662580. Share your questions / positive comments. I will update here Special request to
Tall_Allen
- Please tell : what should I ask ? [
God_Loves_Me
in
Advanced Prostate Cancer
6 months ago
Thyroid disease link with lupus and fibromyalgia
Hello I need to try to understand about my current situation I have underactive thyroid for which I’m prescribed levothyroxine But I have told my drs about feeling so wiped out so tired it hurts falling asleep during the day but not sleeping through the night I have been diagnosed with atrial
Hello I need to try to understand about my current situation I have underactive thyroid for which I’m prescribed levothyroxine But I have told my drs about feeling so wiped out so tired it hurts falling asleep during the day but not sleeping through the night I have been diagnosed with atrial
Dogsareangels
in
Thyroid UK
3 months ago
PMR/GCA and Sjogrens disease
Does anyone have Sjogren’s disease along with PMR/CGA? For months I’ve been struggling with worsening vision in my left eye, and trying to figure out if I was having a flare. The left eye vision is like it was before cataract surgery, worse some times than others, especially after reading. Opthomologist
Does anyone have Sjogren’s disease along with PMR/CGA? For months I’ve been struggling with worsening vision in my left eye, and trying to figure out if I was having a flare. The left eye vision is like it was before cataract surgery, worse some times than others, especially after reading. Opthomologist
Mstiles
in
PMRGCAuk
3 months ago
Gluten and B12 deficiency
Is there a link between B12 deficiency and gluten sensitivity? My neuropathy has massively improved since I started self injecting regularly but I’ve noticed it returns slightly after eating bread, pasta or other foods containing gluten. Alcohol has an effect too I think. Trying to put the pieces of
Is there a link between B12 deficiency and gluten sensitivity? My neuropathy has massively improved since I started self injecting regularly but I’ve noticed it returns slightly after eating bread, pasta or other foods containing gluten. Alcohol has an effect too I think. Trying to put the pieces of
Alilev
in
Pernicious Anaemia Society
3 months ago
Hello, any help welcome
Hi all,I've been told I have an underactive thyroid recently after feeling very tired and achy for a few months, and having a blood test. No treatment as yet, seems more tests are to follow. I've become much more tired, a bit weepy ( not like me at all😔). And, horror of horrors, I'm gaining weight
Hi all,I've been told I have an underactive thyroid recently after feeling very tired and achy for a few months, and having a blood test. No treatment as yet, seems more tests are to follow. I've become much more tired, a bit weepy ( not like me at all😔). And, horror of horrors, I'm gaining weight
cheeseandonioncrisps
in
Thyroid UK
3 months ago
Prostrate Removed, PSA increasing
Hello to all, Is there anyone who had their prostrate removed but PSA is increasing? Oncologist wants to try a new hormonal drug. Radiation was administered after surgery. PSA is increasing. We appreciate your feedback. P.S. Edited profile: “Last CAT Scan was November 2023 - Showed no metastases
Hello to all, Is there anyone who had their prostrate removed but PSA is increasing? Oncologist wants to try a new hormonal drug. Radiation was administered after surgery. PSA is increasing. We appreciate your feedback. P.S. Edited profile: “Last CAT Scan was November 2023 - Showed no metastases
BlessedParchy
in
Advanced Prostate Cancer
6 months ago
Sarcoidosis
Hi I have Lupus and a few other auto diseases , just a quick question is Sarcoidosis any relation and do any of you have it , 💕
Hi I have Lupus and a few other auto diseases , just a quick question is Sarcoidosis any relation and do any of you have it , 💕
whatsit
in
LUPUS UK
3 months ago
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