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Growth inhibitory effect of doxazosin on prostate and bladder cancer cells. Is the serotonin receptor pathway involved?
Doxazosin
, an alpha1-adrenoceptor antagonist, is used for the treatment of benign prostatic hyperplasia (BPH) and hypertension. Alpha-adrenoceptor antagonists also inhibit growth and induce apoptosis in malignant prostatic cells. The apoptotic activity is independent of their capacity to antagonize
Doxazosin
, an alpha1-adrenoceptor antagonist, is used for the treatment of benign prostatic hyperplasia (BPH) and hypertension. Alpha-adrenoceptor antagonists also inhibit growth and induce apoptosis in malignant prostatic cells. The apoptotic activity is independent of their capacity to antagonize
Hidden
in
Advanced Prostate Cancer
2 years ago
Stage 3 CKD and Hashimoto's
Hi All, I have been reading all your posts for awhile and just want to say thank you to all the information everyone supplies. I am Stage 3 CKD with Hashimoto's and an undetermined autoimmune disease. After a year, I finally have a referral to a nephrologist and an endocrinologist. My current doctor
Hi All, I have been reading all your posts for awhile and just want to say thank you to all the information everyone supplies. I am Stage 3 CKD with Hashimoto's and an undetermined autoimmune disease. After a year, I finally have a referral to a nephrologist and an endocrinologist. My current doctor
Grateful2021
in
Kidney Disease
2 years ago
Zinc dipicolinate can be used to smuggle zinc into prostate cancer cells
Abstract Although prostate epithelium concentrates zinc for the purpose of promoting citrate secretion, it loses its capacity to import zinc while undergoing malignant transformation. This exclusion of zinc may be necessary for the viability of prostate cancer, as measures which increase the intracellular
Abstract Although prostate epithelium concentrates zinc for the purpose of promoting citrate secretion, it loses its capacity to import zinc while undergoing malignant transformation. This exclusion of zinc may be necessary for the viability of prostate cancer, as measures which increase the intracellular
Hidden
in
Advanced Prostate Cancer
2 years ago
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Panic or something else?
I feel like I''m not getting enough air. I realize this could be a panic attack as I started having them about 5 years ago. But I take herbal supplements for them and haven't had one in a couple of years now, all I usually get are small symptoms of a pending attack but nothing really bad. Until now.
I feel like I''m not getting enough air. I realize this could be a panic attack as I started having them about 5 years ago. But I take herbal supplements for them and haven't had one in a couple of years now, all I usually get are small symptoms of a pending attack but nothing really bad. Until now.
blueslite
in
Anxiety and Depression Support
2 years ago
6 Red Flags to Watch Out For When Buying Vitamins & Supplements. As per Consumer Lab
I LUV consumer Lab "At ConsumerLab.com, we've purchased, tested, and carefully reviewed the labels of more than 6,000 dietary supplements and found problems with more than 20% of them." 1. Labels that don't tell you how much you're getting There are several situations where this can happen: "Proprietary
I LUV consumer Lab "At ConsumerLab.com, we've purchased, tested, and carefully reviewed the labels of more than 6,000 dietary supplements and found problems with more than 20% of them." 1. Labels that don't tell you how much you're getting There are several situations where this can happen: "Proprietary
MBAnderson
in
Cure Parkinson's
2 years ago
Balinitis
I myself am a doctor. Had similar issue as the comments. Had sti screen: negative Was advised to use antifungal plus antibiotic and hydrocortisone. Made skin very sensitive and uncomfortable. Stopped everything and used sudocrem for 2 weeks. Symptoms all resolved. Skin is mildly wrinkly but improved
I myself am a doctor. Had similar issue as the comments. Had sti screen: negative Was advised to use antifungal plus antibiotic and hydrocortisone. Made skin very sensitive and uncomfortable. Stopped everything and used sudocrem for 2 weeks. Symptoms all resolved. Skin is mildly wrinkly but improved
Zeus366
in
Men's Health Forum (Penis Health)
2 years ago
Bone met shrinking?
Hi all, Is it typical for bone Mets to shrink after ADT? My first scan 7 month ago showed single met on hip bone 2.8 cm x 2.1 cm in size and showed as a solid spot. My most recent scan last week showed the same met is now 1.3 cm x 1.0 cm and now appears as a very faint spot. I didn’t have any other
Hi all, Is it typical for bone Mets to shrink after ADT? My first scan 7 month ago showed single met on hip bone 2.8 cm x 2.1 cm in size and showed as a solid spot. My most recent scan last week showed the same met is now 1.3 cm x 1.0 cm and now appears as a very faint spot. I didn’t have any other
LuisJ
in
Advanced Prostate Cancer
2 years ago
Pain relief
The only support available for the problems my family faces seems to be pain relief especially controlled drugs at present my son is researching traditional herbal medicine much of which appears to be helping.
The only support available for the problems my family faces seems to be pain relief especially controlled drugs at present my son is researching traditional herbal medicine much of which appears to be helping.
Repousae
in
Pain Concern
2 years ago
I Can't Keep Up This Stack :(
Update 6/29/22: Berberine may be neurotoxic. It is off of my stack: https://healthunlocked.com/cure-parkinsons/posts/148177820/finding-some-negatives-on-berberine-i-will-keep-digging ========= You all are so much stronger than I am. Or maybe you are living your lives instead of obsessing over things
Update 6/29/22: Berberine may be neurotoxic. It is off of my stack: https://healthunlocked.com/cure-parkinsons/posts/148177820/finding-some-negatives-on-berberine-i-will-keep-digging ========= You all are so much stronger than I am. Or maybe you are living your lives instead of obsessing over things
Bolt_Upright
in
Cure Parkinson's
2 years ago
Table tennis consultant and Gp
My husband has Aspergillosis , COPD , leaky heart valve , ongoing conditions for 17 years . Starting last November he developed a really distressing cough , not Covid and not an infection , not the Aspergillosis cough , he cannot take anti fungal drugs and is life limiting so was referred to a hospice
My husband has Aspergillosis , COPD , leaky heart valve , ongoing conditions for 17 years . Starting last November he developed a really distressing cough , not Covid and not an infection , not the Aspergillosis cough , he cannot take anti fungal drugs and is life limiting so was referred to a hospice
Daisy55
in
Lung Conditions Community Forum
2 years ago
I Made Coconut Milk Yogurt Yesterday
So I use the Yakult probiotic drink that has so many great qualities (lactobacillus casei Shirota, which is both the probiotic used in the PD study that showed it helped with bowel movements and is also anti-inflammatory, anti-bacterial, anti-viral, and anti-fungal. It has been shown to reduce the EBV
So I use the Yakult probiotic drink that has so many great qualities (lactobacillus casei Shirota, which is both the probiotic used in the PD study that showed it helped with bowel movements and is also anti-inflammatory, anti-bacterial, anti-viral, and anti-fungal. It has been shown to reduce the EBV
Bolt_Upright
in
Cure Parkinson's
2 years ago
Horsetail supplement can Lower Thiamine levels (Possibly affecting HDT protocol)
Please note that many horsetail supplements, which are used for everything from kidney health to bone, sugar and hair health often has thiaminase in it. This lowers thiamine in body. (link below) Special Warning Horsetail has an enzyme called thiaminase in it. The enzyme breaks down thiamine, which
Please note that many horsetail supplements, which are used for everything from kidney health to bone, sugar and hair health often has thiaminase in it. This lowers thiamine in body. (link below) Special Warning Horsetail has an enzyme called thiaminase in it. The enzyme breaks down thiamine, which
Fumaniron
in
Cure Parkinson's
2 years ago
Zeolite ; helpful & not helpful ? Good for cleansing our system , removing metals, or no?
If you have experience with using zeolite can you please share your motivation to and your experience? I have read about the intention of it being anti fungal and “cleansing” but then I’ve read that it does not chelate metals as it claims and can reduce the minerals we need like magnesium. Knowledge
If you have experience with using zeolite can you please share your motivation to and your experience? I have read about the intention of it being anti fungal and “cleansing” but then I’ve read that it does not chelate metals as it claims and can reduce the minerals we need like magnesium. Knowledge
Hidden
in
Cure Parkinson's
2 years ago
Antifungal agent farnesol effective in Parkinson’s?
If an anti fungal agent is effective in stopping Parkinson’s then ask, is Parkinson’s induced or made worse by fungus? Is there fungus among us?
If an anti fungal agent is effective in stopping Parkinson’s then ask, is Parkinson’s induced or made worse by fungus? Is there fungus among us?
Hidden
in
Cure Parkinson's
2 years ago
Viewed on line
Has anyone tried a herbal supplement being advertised by Dr Raphael Perez to help with pain and swelling caused by RA? The product is called Easy Flex. Thank you.
Has anyone tried a herbal supplement being advertised by Dr Raphael Perez to help with pain and swelling caused by RA? The product is called Easy Flex. Thank you.
42Tess
in
NRAS
2 years ago
My Latest Stack: Anybody want to deep dive on protocols?
So this is my latest stack. I think I have a good list now. Now it is time to fine tune it. Get the dosages and timing right. Will any of it help? I hope so. I have not been diagnosed with PD. I have been diagnosed with REM Sleep Behavior Disorder (with other troubling symptoms). I still have a sore
So this is my latest stack. I think I have a good list now. Now it is time to fine tune it. Get the dosages and timing right. Will any of it help? I hope so. I have not been diagnosed with PD. I have been diagnosed with REM Sleep Behavior Disorder (with other troubling symptoms). I still have a sore
Bolt_Upright
in
Cure Parkinson's
2 years ago
Men With Prostate Cancer Benefit From Yoga in the Perioperative Setting. Small study: improved QoL and reduction of inflammatory cytokines
Renal & Urology News Publish Date January 24, 2022 Men With Prostate Cancer Benefit From Practicing Yoga in the Perioperative Setting Bette Weinstein Kaplan Share on Facebook Share on Twitter Share on LinkedIn Share on Reddit Print Share by Email Participants in the yoga group had enhanced physical,
Renal & Urology News Publish Date January 24, 2022 Men With Prostate Cancer Benefit From Practicing Yoga in the Perioperative Setting Bette Weinstein Kaplan Share on Facebook Share on Twitter Share on LinkedIn Share on Reddit Print Share by Email Participants in the yoga group had enhanced physical,
Graham49
in
Advanced Prostate Cancer
2 years ago
Probiotics for Parkinson's disease: Current evidence and future directions 2020
So... I'm taking lactobacillus casei Shirota, which is both the probiotic used in the PD study that showed it helped with bowel movements and is also anti-inflammatory, anti-bacterial, anti-viral, and anti-fungal. It has been shown to reduce the EBV titers in your system too. If you think PD is autoimmune
So... I'm taking lactobacillus casei Shirota, which is both the probiotic used in the PD study that showed it helped with bowel movements and is also anti-inflammatory, anti-bacterial, anti-viral, and anti-fungal. It has been shown to reduce the EBV titers in your system too. If you think PD is autoimmune
Bolt_Upright
in
Cure Parkinson's
3 years ago
Supplements warning: The ‘healthy’ herbal supplement causing severe liver injuries
There is an article in today's Daily Express that warns of the dangers of taking supplements'. The use of alternative medicines and supplements such as Milk Thistle is a question that gets asked a lot on here. It's quite natural for a person who's be diagnosed with a liver related condition, to want
There is an article in today's Daily Express that warns of the dangers of taking supplements'. The use of alternative medicines and supplements such as Milk Thistle is a question that gets asked a lot on here. It's quite natural for a person who's be diagnosed with a liver related condition, to want
Richard-Allen
in
British Liver Trust
3 years ago
Taking too long to recover after circumcision and what to put on scars to help them
Hello, people, please help. I had a circumcision in mid August of 2021 (4 months and 2 weeks ago) due to phimosis. Only in the last week of September (5 weeks after operation) I was able to walk outside somewhat fine. It was hurting a lot in the beginning but by last week of October I was pretty good
Hello, people, please help. I had a circumcision in mid August of 2021 (4 months and 2 weeks ago) due to phimosis. Only in the last week of September (5 weeks after operation) I was able to walk outside somewhat fine. It was hurting a lot in the beginning but by last week of October I was pretty good
ihapidp
in
Men's Health Forum (Penis Health)
3 years ago
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