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AbbVie’s Produodopa approved by SMC to treat Parkinson’s disease patients in Scotland
AbbVie’s Produodopa (foslevodopa-foscarbidopa) has been accepted by the Scottish Medicines Consortium (SMC) for use within NHS Scotland to treat advanced
levodopa
-responsive Parkinson’s disease (PD).
AbbVie’s Produodopa (foslevodopa-foscarbidopa) has been accepted by the Scottish Medicines Consortium (SMC) for use within NHS Scotland to treat advanced
levodopa
-responsive Parkinson’s disease (PD).
Farooqji
in
Cure Parkinson's
2 months ago
Anxiety Strategies
Particularly interesting that
Levodopa
doesn't appear to have any positive impact on anxiety, and may indeed make worse by affecting Serotonin and NE levels! Also of interest is that Anti-Depressant type Meds can exacerbate other PD symptoms.
Particularly interesting that
Levodopa
doesn't appear to have any positive impact on anxiety, and may indeed make worse by affecting Serotonin and NE levels! Also of interest is that Anti-Depressant type Meds can exacerbate other PD symptoms.
AndyMu72
in
Cure Parkinson's
11 months ago
Mucuna Please Read..do the homework
There are 2 good published studies (see below for links) showing wide discrepancies regarding how much actual
Levodopa
content is in the supplement.
There are 2 good published studies (see below for links) showing wide discrepancies regarding how much actual
Levodopa
content is in the supplement.
BuSurfer
in
Cure Parkinson's
10 months ago
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I have been offered Entacapone. I would appreciate hearing your own thoughts and experiences.
I am doing pretty well 7 years post dx, but my neurologist wants to add Entacapone to my 4x
Levodopa
per day regime to shorten my downtime, and I am uncertain whether it’s the way I want to go.
I am doing pretty well 7 years post dx, but my neurologist wants to add Entacapone to my 4x
Levodopa
per day regime to shorten my downtime, and I am uncertain whether it’s the way I want to go.
Buckholt
in
Cure Parkinson's
1 year ago
Patent: Levodopa fractionated dose composition and use
https://patents.google.com/patent/US11439613B2/en There is provided a convenient new treatment of Parkinson disease by a frequent administration of optimal
levodopa
doses mimicking a continuous intravenous or infusion treatment, thus mitigating motor complications; and a new carbidopa/
levodopa
pharmaceutical
https://patents.google.com/patent/US11439613B2/en There is provided a convenient new treatment of Parkinson disease by a frequent administration of optimal
levodopa
doses mimicking a continuous intravenous or infusion treatment, thus mitigating motor complications; and a new carbidopa/
levodopa
pharmaceutical
Hidden
in
Cure Parkinson's
1 year ago
Human Static Magnetic Stimulation, patients report improvement.
While this study reported no significant objective benefit (moderate evidence of absence), but significant subjective benefit (moderate evidence) for the treatment of
levodopa
-induced dyskinesias in PD.
While this study reported no significant objective benefit (moderate evidence of absence), but significant subjective benefit (moderate evidence) for the treatment of
levodopa
-induced dyskinesias in PD.
House2
in
Cure Parkinson's
5 months ago
Vodobatinib
Anyone heard about this? Note on *SPARC's Vodobatinib* for *Parkinson's Disease*: SPARC, a pioneering force in the pharmaceutical arena, is making significant strides with its flagship *Neurological* program asset, Vodobatinib. Currently, Vodobatinib is undergoing trials for three critical indications
Anyone heard about this? Note on *SPARC's Vodobatinib* for *Parkinson's Disease*: SPARC, a pioneering force in the pharmaceutical arena, is making significant strides with its flagship *Neurological* program asset, Vodobatinib. Currently, Vodobatinib is undergoing trials for three critical indications
JayPwP
in
Cure Parkinson's
4 months ago
mucuna or sinemet?
why should it be different to take
levodopa
from mucuna or take it from sinemet? Isn't it the same chemical formula? L-DOPA/Formula : C9H11NO4
why should it be different to take
levodopa
from mucuna or take it from sinemet? Isn't it the same chemical formula? L-DOPA/Formula : C9H11NO4
michelagvolpe
in
Cure Parkinson's
1 year ago
Interesting Article: Promising new remedies for Parkinson's disease
Update:
I read and researched as I was posting this. I am happy they put NR and PEA in their article, but I think they got a little over their skis stating they had found a "
A dynamic quartet
" [u]
Update Again! Please see Park Bear's Citicoline Warning
[/u] https://healthunlocked.com
Update:
I read and researched as I was posting this. I am happy they put NR and PEA in their article, but I think they got a little over their skis stating they had found a "
A dynamic quartet
" [u]
Update Again! Please see Park Bear's Citicoline Warning
[/u] https://healthunlocked.com
Bolt_Upright
in
Cure Parkinson's
4 months ago
PD and B1
I am taking carbidopa/
levodopa
for three years now. I have read ”Parkinson’s and the B1 therapy“ on Amazon and am evaluating my next steps. At my last visit to the Neurologist, she mentioned something that could put the cabidopa/
levodopa
“on high octane”.
I am taking carbidopa/
levodopa
for three years now. I have read ”Parkinson’s and the B1 therapy“ on Amazon and am evaluating my next steps. At my last visit to the Neurologist, she mentioned something that could put the cabidopa/
levodopa
“on high octane”.
Hidden
in
Cure Parkinson's
1 year ago
Has anyone had success reducing levodopa-induced Dyskinesias after using Dr. Laurie Mischley’s regimen? (High DHA Fish Oil, Citicholine)
I would like to know if anyone has been successful in reducing or eliminating
levodopa
-induced dyskinesias after using Dr. Laurie Mischley's regimen (High DHA Fish Oil and Citicholine). There were quite a number of posts here about 2 months ago.
I would like to know if anyone has been successful in reducing or eliminating
levodopa
-induced dyskinesias after using Dr. Laurie Mischley's regimen (High DHA Fish Oil and Citicholine). There were quite a number of posts here about 2 months ago.
PNWpWp2014d
in
Cure Parkinson's
2 months ago
atypical parkinson’s diagnosis and no treatment relief
my neurologist has put me on carbidopa/
levodopa
, the dosage is 4 every four hours, four times a day. I have tremors I am unbalanced, my speech is affected, I cannot write anymore, and I am extremely emotional.
my neurologist has put me on carbidopa/
levodopa
, the dosage is 4 every four hours, four times a day. I have tremors I am unbalanced, my speech is affected, I cannot write anymore, and I am extremely emotional.
Doneanddone
in
Neuro Support
10 months ago
Could Psychedelics help in Parkinsons Disease treatment?
- Medication resistance - For some patients who do not fully respond to
levodopa
and other drugs, reopening periods may help brains develop workarounds or harness residual neuroplasticity to further improve symptoms.
- Medication resistance - For some patients who do not fully respond to
levodopa
and other drugs, reopening periods may help brains develop workarounds or harness residual neuroplasticity to further improve symptoms.
pdpatient
in
Cure Parkinson's
9 months ago
Insomnia
Currently I'm on
levodopa
/carbidopa, safinamide and opicapona. Do you think It can be related with B1? Or maybe DBS tunning? Thanks for any advice.
Currently I'm on
levodopa
/carbidopa, safinamide and opicapona. Do you think It can be related with B1? Or maybe DBS tunning? Thanks for any advice.
carlosgarcia2048
in
Cure Parkinson's
2 months ago
Progression
I am taking carbidopa/
levodopa
which helps with the tremors, and I take muscle relaxant for pain and cramps in my legs.
I am taking carbidopa/
levodopa
which helps with the tremors, and I take muscle relaxant for pain and cramps in my legs.
horseandwolf
in
PSP Association
11 months ago
Weaning off high dose Pramipexole
My neurologist addressed it by a pramipexole vacation and prescribed carbidopa
levodopa
for 3 months. Seemed odd as it is a dopamine drug but it worked to knock back the symptoms to the evening. . Then over time I started adapting and required higher and higher doses.
My neurologist addressed it by a pramipexole vacation and prescribed carbidopa
levodopa
for 3 months. Seemed odd as it is a dopamine drug but it worked to knock back the symptoms to the evening. . Then over time I started adapting and required higher and higher doses.
lessergoldfinch
in
Restless Legs Syndrome
11 months ago
15-Year Subthalamic Deep Brain Stimulation outcome in a Parkinson's disease patient with Parkin gene mutation: a case report
Levodopa
was started, and during the following 10 years, he reported good motor symptoms control, with only mild modification of
levodopa
intake and pramipexole introduction. In 2005, he developed disabling motor fluctuations and dyskinesia.
Levodopa
was started, and during the following 10 years, he reported good motor symptoms control, with only mild modification of
levodopa
intake and pramipexole introduction. In 2005, he developed disabling motor fluctuations and dyskinesia.
Hidden
in
Cure Parkinson's
1 year ago
Does iron in hard water interfere with levodopa uptake?
We are told to avoid supplements containing iron when taking
levodopa
because it interferes with
levodopa
uptake. We will be vacationing in an area where the tap water has high iron content that affects the taste of the water and stains the sinks.
We are told to avoid supplements containing iron when taking
levodopa
because it interferes with
levodopa
uptake. We will be vacationing in an area where the tap water has high iron content that affects the taste of the water and stains the sinks.
Ashti
in
Cure Parkinson's
11 months ago
Why not give Hyperbaric Oxygen Therapy (HBOT) as Adjunctive Therapy a Try?
LEVODOPA
REDUCTION FROM 2400 MG DAILY DOWN TO 1400 MG SUSTAINED. SOME DAYS 1,000 MG, THERE WERE 800 EVEN 600, LOWEST 400 MG 5. MY DOSING SCHEDULE HAS ALWAYS BEEN EVERY 3 HOURS STARTING AT 0500. AT THE TIME I GOT ON THE TASIGNA TRIAL I WAS GETTING ONLY 2.5 HOURS ON MY GOOD DAYS.
LEVODOPA
REDUCTION FROM 2400 MG DAILY DOWN TO 1400 MG SUSTAINED. SOME DAYS 1,000 MG, THERE WERE 800 EVEN 600, LOWEST 400 MG 5. MY DOSING SCHEDULE HAS ALWAYS BEEN EVERY 3 HOURS STARTING AT 0500. AT THE TIME I GOT ON THE TASIGNA TRIAL I WAS GETTING ONLY 2.5 HOURS ON MY GOOD DAYS.
Isthistheone
in
Cure Parkinson's
9 months ago
AAN 2023: Amneal’s IPX203 shows promise for Parkinson’s disease patients
Academy of Neurology (AAN) 2023 Annual Meeting, Amneal presented new data evaluating IPX203 (carbidopa +
levodopa
, CD/LD) in a nine-month open-label extension (OLE) study in Parkinson’s disease (PD) patients with motor fluctuations (NCT03877510).
Academy of Neurology (AAN) 2023 Annual Meeting, Amneal presented new data evaluating IPX203 (carbidopa +
levodopa
, CD/LD) in a nine-month open-label extension (OLE) study in Parkinson’s disease (PD) patients with motor fluctuations (NCT03877510).
Farooqji
in
Cure Parkinson's
1 year ago
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