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Interferon
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Anagrelide or Peg Interferon
The doc has recommended either anagrellde or Peg
Interferon
. I have PV. I'm going to phone the nurse today and get her thoughts and advice. I have the MPN leaflets on both, and know about the possible side effects, but I'm tending towards Peg. Thoughts please! Many thanks Sandra
The doc has recommended either anagrellde or Peg
Interferon
. I have PV. I'm going to phone the nurse today and get her thoughts and advice. I have the MPN leaflets on both, and know about the possible side effects, but I'm tending towards Peg. Thoughts please! Many thanks Sandra
Splb3317
in
MPN Voice
4 years ago
Genetic clue to severe Covid: “It is part of the system that makes your immune cells more angry, and more inflammatory”...sound like lupus ?
:) 'Two other recent studies published in the journal Science have also implicated
interferon
in Covid cases, through both genetic mutations and an autoimmune disorder that affects its production.' https://www.bbc.co.uk/news/health-54832563 xxx
:) 'Two other recent studies published in the journal Science have also implicated
interferon
in Covid cases, through both genetic mutations and an autoimmune disorder that affects its production.' https://www.bbc.co.uk/news/health-54832563 xxx
eekt
in
LUPUS UK
4 years ago
Pegasys and Blood Pressure Medication
The nurse that put me on the medication didn’t seem to know much about
interferon
at all.
The nurse that put me on the medication didn’t seem to know much about
interferon
at all.
swimswam
in
MPN Voice
4 years ago
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Starting meds & worried
Interferon
by injection is looking most likely but I’m waiting for face to face appointment to decide & to sign consent form. Any advice would be greatly appreciated x
Interferon
by injection is looking most likely but I’m waiting for face to face appointment to decide & to sign consent form. Any advice would be greatly appreciated x
DoubleF79
in
MPN Voice
4 years ago
Hair loss
Would switching to
interferon
make any difference any ladies out there for any advice I don't want to be a badly woman.
Would switching to
interferon
make any difference any ladies out there for any advice I don't want to be a badly woman.
ciye
in
MPN Voice
4 years ago
Interferon in Polycythemia Vera (PV) Yields Improved Myelofibrosis-Free and Overall Survival
« Conclusion: Our results support early use of rIFN-a as a safe, disease-modifying treatment of rigorously defined PV to delay and potentially prevent Post PV myelofibrosis, and prolong overall survival of PV pts » https://ash.confex.com/ash/2020/webprogram/Paper141796.html
« Conclusion: Our results support early use of rIFN-a as a safe, disease-modifying treatment of rigorously defined PV to delay and potentially prevent Post PV myelofibrosis, and prolong overall survival of PV pts » https://ash.confex.com/ash/2020/webprogram/Paper141796.html
Manouche
in
MPN Voice
4 years ago
Update. Clinical trial finds inhaled immune response protein increases odds of recovery for hospitalised COVID-19 patients
The type I interferons (
interferon
-α and
interferon
-β) have been tested against coronavirus infections in vitro, with encouraging results.
The type I interferons (
interferon
-α and
interferon
-β) have been tested against coronavirus infections in vitro, with encouraging results.
2greys
in
Lung Conditions Community Forum
4 years ago
Arsenic with interferon
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579737/ Does anyone know if there is or will be a clinical trial from this research?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579737/ Does anyone know if there is or will be a clinical trial from this research?
markgenious1981
in
Positive Wellbeing During Self-Isolation
4 years ago
Germline genetic factors influence the outcome of interferon-α therapy in polycythemia vera
«
Interferon
-α (IFN-α)–based therapies can induce sustained hematologic responses (HRs) and durable molecular responses (MRs) in polycythemia vera (PV) and other myeloproliferative neoplasms (MPNs).
«
Interferon
-α (IFN-α)–based therapies can induce sustained hematologic responses (HRs) and durable molecular responses (MRs) in polycythemia vera (PV) and other myeloproliferative neoplasms (MPNs).
Manouche
in
MPN Voice
4 years ago
Experience on interferon.
My partner has hep B and the consultant has been advising on treatment and suggested
interferon
. He is concerned about the side effects especially in light of his job as a driver. I appreciate everyone is different but please can you let me know of experience on
interferon
treatment. Thanks.
My partner has hep B and the consultant has been advising on treatment and suggested
interferon
. He is concerned about the side effects especially in light of his job as a driver. I appreciate everyone is different but please can you let me know of experience on
interferon
treatment. Thanks.
Maisy76
in
British Liver Trust
4 years ago
New hope to cure patients with MPNs
(https://doi.org/10.1084/jem.20201268) combine arsenic and
interferon
α to deliver a knockout punch to MPN stem cells and provide new hope to cure patients with MPNs. » « Additionally, after IFNα+ATO treatment was withdrawn, primary mice were monitored for the reemergence of disease.
(https://doi.org/10.1084/jem.20201268) combine arsenic and
interferon
α to deliver a knockout punch to MPN stem cells and provide new hope to cure patients with MPNs. » « Additionally, after IFNα+ATO treatment was withdrawn, primary mice were monitored for the reemergence of disease.
Manouche
in
MPN Voice
4 years ago
If I had known then, how would I have lived my life differently?
Just thinking out loud here... Recently, I had the realization that my MS symptoms (foot drop) began @ 1987 rather than when I was diagnosed in 2009. I did see a neurologist at the time but MS wasn’t even considered. There were 3 treatment options in 2009 (2 interferons and copaxone). There were essentially
Just thinking out loud here... Recently, I had the realization that my MS symptoms (foot drop) began @ 1987 rather than when I was diagnosed in 2009. I did see a neurologist at the time but MS wasn’t even considered. There were 3 treatment options in 2009 (2 interferons and copaxone). There were essentially
erash
in
My MSAA Community
4 years ago
Lowering platelets
I have ET and have been stable on Peg
interferon
for a few years now but my last couple of blood test shows my platelets are dropping, my latest has dropped below the average?
I have ET and have been stable on Peg
interferon
for a few years now but my last couple of blood test shows my platelets are dropping, my latest has dropped below the average?
Gunner73
in
MPN Voice
4 years ago
Interferon-Alpha Reduces Myelofibrosis Risk, Mortality Rate in Low- and High-Risk Polycythemia Vera
The rate of Myelofibrosis Free Survival of low-risk patients was significantly higher in those treated with IFN (84%) than in the HU (65%) and phlebotomy (55%) groups” https://www.onclive.com/view/
interferon
-alpha-reduces-myelofibrosis-risk-mortality-rate-in-low--and-high-risk-polycythemia-vera
The rate of Myelofibrosis Free Survival of low-risk patients was significantly higher in those treated with IFN (84%) than in the HU (65%) and phlebotomy (55%) groups” https://www.onclive.com/view/
interferon
-alpha-reduces-myelofibrosis-risk-mortality-rate-in-low--and-high-risk-polycythemia-vera
Manouche
in
MPN Voice
4 years ago
Question for those taking PEG Interferon
I started on PEG
Interferon
at start of the year injecting 135mcg (it’s been slow at reducing levels) to treat my JAK2 PV.
I started on PEG
Interferon
at start of the year injecting 135mcg (it’s been slow at reducing levels) to treat my JAK2 PV.
Tylerdog1
in
MPN Voice
4 years ago
Jak2 allele burden results
I have had PV since 2005 and been on
Interferon
most of the time. Logically I think 31% is good. In fact great. Am I right? Should I dance for joy? I haven't got the medical knowledge to relate it to the bigger picture.
I have had PV since 2005 and been on
Interferon
most of the time. Logically I think 31% is good. In fact great. Am I right? Should I dance for joy? I haven't got the medical knowledge to relate it to the bigger picture.
MPort
in
MPN Voice
4 years ago
IS DEPRESSION A SYMPTOM OR SIDE EFFECT IN MPNS?
However, on the
Interferon
Alpha, it rapidly grew worse in my own case.
However, on the
Interferon
Alpha, it rapidly grew worse in my own case.
socrates_8
in
MPN Voice
4 years ago
Stopped my treatment for ET
I have ET and been on
interferon
Alpha for 11 years changed recently to peg, after a month on peg my platelets went low so stopped treatment in July.Over the last 3months having bloods done every four weeks, my platelets have been around the 300, so been great.consultant phoned today after having my
I have ET and been on
interferon
Alpha for 11 years changed recently to peg, after a month on peg my platelets went low so stopped treatment in July.Over the last 3months having bloods done every four weeks, my platelets have been around the 300, so been great.consultant phoned today after having my
Jbut
in
MPN Voice
4 years ago
‘Significant’ Covid-19 drug breakthrough.
ILC Therapeutics, a Scottish biotech company, has announced that its unique synthetic
Interferon
called Alfacyte™ is more effective at preventing the spread of SARS-CoV-2 in cell culture than other commercially-available Interferons such as
Interferon
Alpha 2 and
Interferon
Beta 1a.
ILC Therapeutics, a Scottish biotech company, has announced that its unique synthetic
Interferon
called Alfacyte™ is more effective at preventing the spread of SARS-CoV-2 in cell culture than other commercially-available Interferons such as
Interferon
Alpha 2 and
Interferon
Beta 1a.
2greys
in
Lung Conditions Community Forum
4 years ago
Allele burden results on Pegasys
I thought that some people might be interested in this because of the potential for molecular remission with
interferon
. I don't quite know what to make of this and neither, I suspect, does my mpn specialist. At least things are moving in an encouraging direction.
I thought that some people might be interested in this because of the potential for molecular remission with
interferon
. I don't quite know what to make of this and neither, I suspect, does my mpn specialist. At least things are moving in an encouraging direction.
charl17
in
MPN Voice
4 years ago
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